The effect of erythrocyte-derived microvesicles on the malignant potential of gastric cancer
| Project/Area Number |
16K19948
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Arita Tomohiro 京都府立医科大学, 医学(系)研究科(研究院), 助教 (00756794)
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| Research Collaborator |
KONISHI Hirotaka 京都府立医科大学, 消化器外科, 助教
KOMATSU Shuhei 京都府立医科大学, 消化器外科, 特任講師
SHIOZAKI Atsushi 京都府立医科大学, 消化器外科, 講師
ICHIKAWA Daisuke 山梨大学, 総合研究部, 教授
OTSUJI Eigo 京都府立医科大学, 消化器外科, 教授
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| Project Period (FY) |
2016-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | extracellular vesicle / erythrocyte / exosome / gastric cancer / エクソソーム / 赤血球 / 消化器癌 / 血球 / 胃十二指腸外科学 |
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| Outline of Final Research Achievements |
Erythrocyte-derived microvesicles (EDM) were ingested into the cellular cytoplasm using fluorescence microscopy. EDMs from patients with gastric cancer enhanced the adhesive, wound healing and migratory ability of gastric cancer cell. Several oncogenes were up-regulated in EDM-ingested gastric cancer cell.
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Report
(3 results)
Research Products
(6 results)
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[Presentation] Exogenous Factors in Development of Peritoneal Metastasis of Gastric Cancer2016
Author(s)
Tomohiro Arita, Daisuke Ichikawa, Hirotaka Konishi, Katsutoshi Shoda, Junichi Hamada, Hidekazu Hitamoto, Yuji Fujita, Shinpei Ogino, Toshiyuki Kosuga, Shuhei Komatsu, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto, Eigo Otsuji
Organizer
第27回日本消化器癌発生学会
Place of Presentation
鹿児島県、城山観光ホテル
Year and Date
2016-09-15
Related Report
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