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Changes in cerebellar network at resting period and investigation of cognitive dysfunction

Research Project

Project/Area Number 16K20018
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Neurosurgery
Research InstitutionUniversity of the Ryukyus

Principal Investigator

Shiroma Ayano  琉球大学, 医学(系)研究科(研究院), 非常勤講師 (50751567)

Project Period (FY) 2016-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2017: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Keywords安静時脳活動 / 認知機能 / 小脳腫瘍 / 認知機能障害 / 安静時脳活動データ / 機能的結合性 / 脳腫瘍学
Outline of Final Research Achievements

Neuropsychological assessments were carried out on 5 patients with benign cerebellar tumors, as well as on a control group consisting of 10 healthy controls. Executive function score before operation was markedly decreased in cerebellar tumor patients compared with healthy controls. As a result of correlation analysis of the BOLD waveform on functional binding between brain regions in resting brain activity, each module of frontal lobe, hippocampus and cerebellar were independent in healthy controls. On the contrary, patients increased cortical association of cerebrum to cerebrum and cerebrum to cerebellum.

Report

(3 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report

URL: 

Published: 2016-04-21   Modified: 2019-03-29  

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