Contribution of Microstructures and Compositions to the Mechanical Properties of Human Dentin
Project/Area Number |
16K20454
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Conservative dentistry
|
Research Institution | Osaka University |
Principal Investigator |
SHINNO YUKO 大阪大学, 歯学部附属病院, 医員 (80736249)
|
Project Period (FY) |
2016-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 歯学 / 象牙質 / ハイドロキシアパタイト / コラーゲン / ペントシジン / 構造パラメータ / 材質パラメータ / 保存修復学 |
Outline of Final Research Achievements |
In the evaluation of the mechanical strength of dentin, not only the evaluation of the anisotropy of dentin tubule (structural parameter) but also the evaluation of quality parameters such as the c-axis orientation of hydroxyapatite of dentin and non-enzymatic cross-links known as advanced glycation end-products (AGEs)in dentin collagen. In the evaluation of the apatite orientation, the preferential alignment of the c-axis of apatite was perpendicular to the dentinal tubule orientation. The mechanical strength significantly increased in the specimens with strong alignment of their apatite c-axis.The pentosidine content in crown dentin significantly increased with aging, while that in root dentin did not increase significantly. The results also showed significant negative correlation between the pentosidine content and the mechanical strength
|
Report
(3 results)
Research Products
(6 results)