| Project/Area Number |
16K20497
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Prosthodontics/ Dental materials science and
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2016-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 抗菌性 / 薬剤徐放 / ポリマー / 義歯 |
|---|
| Outline of Final Research Achievements |
In this study, cetylpyridinium chloride (CPC)-loaded polymer particles, that can release CPC continuously by recharging, were incorporated into a commercial PMMA denture base resin, and their CPC-recharge profiles, antifungal properties, and flexural strengths were evaluated in vitro. Incorporation of CPC-loaded polymer particles at 20(wt)% was effective to maintain CPC-release from the PMMA resin by recharging, and achieve inhibitory effects against adherence of C. albicans on the surface, without hampering the flexural strength of resin.
|
