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Neural Mechanism of Individual Differences in Working Memory Capacity: Studies from a Perspective of Functional Hierarchical Organization of the Brain

Research Project

Project/Area Number 16K21689
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Cognitive science
Experimental psychology
Research InstitutionShimane University (2018-2019)
National Institute of Information and Communications Technology (2016-2017)

Principal Investigator

Minamoto Takehiro  島根大学, 学術研究院人間科学系, 准教授 (40611306)

Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsワーキングメモリ / 前頭前野 / 脳機能画像法 / 個人差 / 機能的結合 / 脳機能 / 注意 / 前頭葉 / 実験心理学 / 認知科学
Outline of Final Research Achievements

The present study elucidated neural mechanism mediating individual differences in working memory capacity. Mainly focusing on function of the lateral prefrontal cortex (lPFC), the present project not only investigated activity level of the lPFC, but also functional coupling of the lPFC during task-related and task-free states. Three possible neural mechanisms are proposed to mediate individual differences in working memory capacity, which need to be validated by further investigations.

Academic Significance and Societal Importance of the Research Achievements

近年では,前頭前野の活動だけでなく,前頭前野と他の脳領域との連携が,高度な認知機能にとって重要な役割を果たすことが示されている。本研究により,ワーキングメモリ機能の個人差においても領域間の連携が関与することが示唆されたことから,認知機能の改善を目指すプログラムを考案する上では,これらの神経メカニズムを念頭に置きながら研究開発を進めるべきであると言える。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (17 results)

All 2019 2018 2017 2016 Other

All Journal Article (4 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results) Book (3 results) Remarks (2 results)

  • [Journal Article] Activity in the dorsal ACC causes deterioration of sequential motor performance due to anxiety2019

    • Author(s)
      Ganesh Gowrishankar、Minamoto Takehiro、Haruno Masahiko
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 4287-4287

    • DOI

      10.1038/s41467-019-12205-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Moderate sedation induced by general anaesthetics disrupts audio-spatial feature binding with sustained P3 components in healthy humans2018

    • Author(s)
      Minamoto, T., Ikeda, T., Kang, H., Ito, H., Vitayaburananont, P., Nakae, A., Hagihira, S., Fujino, Y., Mashimo, T., and Osaka, M.
    • Journal Title

      Neuroscience of Consciousness

      Volume: 4 Issue: 1

    • DOI

      10.1093/nc/niy002

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of sedation on subjective perception of pain intensity and autonomic nervous responses to pain: A preliminary study2017

    • Author(s)
      Kang Hongling、Nakae Aya、Ito Hiroshi、Vitayaburananont Piyasak、Minamoto Takehiro、Ikeda Takashi、Osaka Mariko、Mashimo Takashi、Fujino Yuji、Hagihira Satoshi
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 9 Pages: e0183635-e0183635

    • DOI

      10.1371/journal.pone.0183635

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Neural mechanisms of individual differences in working memory capacity: Observations from functional neuroimaging studies2017

    • Author(s)
      Minamoto, T., Tsubomi, H., and Osaka, N.
    • Journal Title

      Current Directions in Psychological Science

      Volume: 印刷中

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 認知的なストレスと情動的なストレスは脳のどこで統合されるのか?2019

    • Author(s)
      源健宏・春野雅彦
    • Organizer
      日本心理学会第83回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 低酸素環境下ではリスキーな判断をしやすくなる2019

    • Author(s)
      川上直秋・辻本健彦・源健宏
    • Organizer
      日本心理学会第83回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 音楽性を支える脳の仕組み2018

    • Author(s)
      源 健宏
    • Organizer
      日本音楽教育学会 第49回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 加害者と結びつくポジティブな感情情報の想起は許しを促すのか?2018

    • Author(s)
      源 健宏
    • Organizer
      日本心理学会第82回大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 怒りがもたらす負の記憶検索の向進と正の記憶検索の抑圧2018

    • Author(s)
      源健宏・春野雅彦
    • Organizer
      日本心理学会第81回大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 感情的妨害効果の制御に関わる前部帯状回とその機能分離:感情と認知ストレスを付加的に操作したfMRI研究2017

    • Author(s)
      源健宏・春野雅彦
    • Organizer
      第40回日本神経科学大会
    • Related Report
      2017 Research-status Report
  • [Presentation] The Prefrontal Cortex, A Critical Source for Individual Differences in Working Memory Capacity.2016

    • Author(s)
      Minamoto, T.
    • Organizer
      The 31st International Congress of Psychology
    • Place of Presentation
      Pacifico Yokohama (Minatomirai, Yokohama-shi Nishi-ku, Kanagawa, Japan)
    • Year and Date
      2016-07-25
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] An Effect of Positive Emotion on Working Memory Depends on Stimulus Type and Task Difficulty: An fMRI Study.2016

    • Author(s)
      Minamoto, T., Yaoi, K., Osaka, M. and Osaka, N.
    • Organizer
      第40回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市西区みなとみらい)
    • Year and Date
      2016-07-21
    • Related Report
      2016 Research-status Report
  • [Book] 心理学実験2019

    • Author(s)
      山口 真美、金沢 創、河原 純一郎
    • Total Pages
      240
    • Publisher
      遠見書房
    • ISBN
      9784866160566
    • Related Report
      2019 Annual Research Report
  • [Book] 生理心理学と精神生理学 第III巻 展開2018

    • Author(s)
      堀 忠雄、尾崎 久記、室橋 春光、苧阪 満里子
    • Total Pages
      380
    • Publisher
      北大路書房
    • ISBN
      4762830194
    • Related Report
      2018 Research-status Report
  • [Book] 絆の音楽性2018

    • Author(s)
      スティーヴン マロック、コルウィン トレヴァーセン、根ケ山 光一、今川 恭子
    • Total Pages
      656
    • Publisher
      音楽之友社
    • ISBN
      9784276139091
    • Related Report
      2017 Research-status Report
  • [Remarks] Takehiro's HP

    • URL

      http://hp4takehiro.html.xdomain.jp/

    • Related Report
      2019 Annual Research Report 2017 Research-status Report
  • [Remarks] Takehiro's HP

    • URL

      http://hp4takehiro.html.xdomain.jp/index.html

    • Related Report
      2018 Research-status Report 2016 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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