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Toward development of mobile diagnostic system via human volatolome for disease screening(Fostering Joint International Research)

Research Project

Project/Area Number 16KK0143
Research Category

Fund for the Promotion of Joint International Research (Fostering Joint International Research)

Allocation TypeMulti-year Fund
Research Field Measurement engineering
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Arakawa Takahiro  東京医科歯科大学, 生体材料工学研究所, 講師 (50409637)

Project Period (FY) 2017 – 2019
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Keywordsイメージング / モバイル装置 / CMOS / 酵素 / モバイルデバイス / 蛍光イメージング / 計測工学 / 生体計測 / モバイル診断 / 流体デバイス / 光学
Outline of Final Research Achievements

I visited Prof. Ozcan's laboratory at the University of California Los Angeles (UCLA) for international collaborative research. I focused on the realization of a novel imaging system for the measurement and imaging of continuous, bio-derived components with high selectivity for bio-derived chemical components. I was able to construct a system for imaging volatile components released by living organisms in response to disease and the body's metabolic and physiological states. I was able to miniaturize this imaging system and develop a new mobile imaging system, which allowed me to pursue international collaborative research. I gained a lot of skills and knowledge through my research. And we are continuing our research.

Academic Significance and Societal Importance of the Research Achievements

外国の研究室での共同研究を通して、日本以外の研究室における研究に対する考え方や取り組み方について身をもって学ぶことができた。研究成果においては基盤研究での研究成果をもとに、現地での実験を行い、教授やポスドクなどと議論をし、新しい研究プロジェクトの立案などの経験もできた。研究成果としては新しい計測装置を一から作製することができ、現在評価を進めている。これまでの専門と違う研究者とも共同研究することができ学術的にも意義の高い研究を実施することができた。また、所属していた研究グループ以外の研究者とのネットワークを構築することもでき、今後更なる研究の発展を目指していきたい。

Report

(2 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (6 results)

All 2020 2019 2017

All Int'l Joint Research (1 results) Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results) Book (1 results)

  • [Int'l Joint Research] カリフォルニア大学ロサンゼルス校(米国)2017

    • Year and Date
      2017-07-31
    • Related Report
      2019 Annual Research Report
  • [Journal Article] 性化学しガスセンサとガス濃縮装置を用いた経皮エタノールガス計測システム2020

    • Author(s)
      荒川貴博、青田崇志、當麻浩司、三林浩二
    • Journal Title

      電気学会論文誌E センサ・マイクロマシン部門誌

      Volume: 7 Pages: 0-0

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Real-time monitoring of skin ethanol gas by a high-sensitivity gas phase biosensor (bio-sniffer) for the non-invasive evaluation of volatile blood compounds.2019

    • Author(s)
      Arakawa T, Suzuki T, Tsujii M, Iitani K, Chien PJ, Ye M, Toma K, Iwasaki Y, Mitsubayashi K
    • Journal Title

      Biosens Bioelectron

      Volume: 129 Pages: 245-253

    • DOI

      10.1016/j.bios.2018.09.070

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Bio-fluorometric sniff-cam (gas-imaging system) for human breath and skin gas analysis2020

    • Author(s)
      Takahiro Arakawa and Kohji Mitsubayashi
    • Organizer
      Pittcon 2020
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mouthguard biosensor (cavitas sensor) toward monitoring of salivary glucose in oral cavity2019

    • Author(s)
      Takahiro Arakawa
    • Organizer
      Bio4Apps2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Book] Chemical, Gas, and Biosensors for Internet of Things and Related Applications 1st Edition2019

    • Author(s)
      Takahiro Arakawa, Koji Toma, Kohji Mitsubayashi
    • Total Pages
      408
    • Publisher
      Elsevior
    • ISBN
      9780128154090
    • Related Report
      2019 Annual Research Report

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Published: 2017-03-15   Modified: 2021-02-19  

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