| Project/Area Number |
17012025
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | Japanese Foundation For Cancer Research |
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Principal Investigator |
YAMORI Takao Japanese Foundation For Cancer Research, 癌化学療法センター・分子薬理部, 部長 (60200854)
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| Co-Investigator(Kenkyū-buntansha) |
UEHARA Yoshimasa 岩手医科大学, 薬学部, 教授 (50160213)
YOSHIDA Minoru 独立行政法人理化学研究所, 化学遺伝学研究室, 主任研究員 (80191617)
IMOTO Masaya 慶應義塾大学, 理工学部, 教授 (60213253)
SEIMIYA Hiroyuki 財団法人癌研究会, 癌化学療法センター分子生物治療研究部, 部長 (50280623)
MIZUKAMI Tamio 長浜バイオ大学, バイオサイエンス学部, 教授 (80367896)
KAWADA Manabu 財団法人微生物化学研究会, 微生物化学研究センター, ユニット長 (20300808)
OSADA Hiroyuki 独立行政法人理化学研究所, 抗生物質研究室, 主任研究員 (80160836)
MATSUURA Masaaki 財団法人癌研究会, 癌研究所がんゲノム研究部, 部長 (40173794)
FUKAZAWA Hidesuke 国立感染症研究所, 生物活性物質部, 室長 (10218878)
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| Project Period (FY) |
2005 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥249,000,000 (Direct Cost: ¥249,000,000)
Fiscal Year 2009: ¥48,200,000 (Direct Cost: ¥48,200,000)
Fiscal Year 2008: ¥48,200,000 (Direct Cost: ¥48,200,000)
Fiscal Year 2007: ¥48,200,000 (Direct Cost: ¥48,200,000)
Fiscal Year 2006: ¥48,200,000 (Direct Cost: ¥48,200,000)
Fiscal Year 2005: ¥56,200,000 (Direct Cost: ¥56,200,000)
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| Keywords | 化合物 / 分子標的 / 阻害剤 / スクリーニング / 研究支援 / データベース / 抗がん剤 / ケミカルバイオロジー |
|---|
| Research Abstract |
To support researchers who have new compounds, we evaluated biological activities of their compounds (~1000) by our screening system and provided them the results. Most of the results were published with their consent. We developed "SCADS inhibitor kit", a library including 300 compounds with known mechanisms of action, and distributed it to applicants to encourage their chemical biology studies. We developed another library of 200 new compounds deposited by researchers and distributed it to applicants. We collected information on new molecular targeted anticancer drugs and provided it via web pages.
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