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Analysis of developmental mechanisms based on functional genomic information of the nematode C. elegans

Research Project

Project/Area Number 17017038
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

SUGIMOTO Asako  The Institute of Physical and Chemical Research, 発生ゲノミクス研究チーム, チームリーダー (80281715)

Co-Investigator(Kenkyū-buntansha) ONAMI Shuichi  独立行政法人理化学研究所, 発生システムモデル化研究チーム, チームリーダー (50348843)
KIMURA Akatsuki  慶應義塾大学, 大学院・理工学研究科, 助手 (10365447)
KYODA Koji  独立行政法人理化学研究所, 合成ゲノミクス研究チーム, 研究員 (30415145)
Project Period (FY) 2005 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥101,800,000 (Direct Cost: ¥101,800,000)
Fiscal Year 2009: ¥19,200,000 (Direct Cost: ¥19,200,000)
Fiscal Year 2008: ¥19,100,000 (Direct Cost: ¥19,100,000)
Fiscal Year 2007: ¥18,900,000 (Direct Cost: ¥18,900,000)
Fiscal Year 2006: ¥18,600,000 (Direct Cost: ¥18,600,000)
Fiscal Year 2005: ¥26,000,000 (Direct Cost: ¥26,000,000)
Keywordsゲノム / 遺伝子 / 発生・分化 / モデル化 / ライブイメージング / 画像処理 / バイオイメージインフォマティクス / 線虫 / RNAi / 細胞分裂 / 表現型 / 胚発生
Research Abstract

To understand the genetic networks that control animal development, the following were performed using the early embryogenesis of the nematode C.elegans
as a model system. 1) Development of tools (such as GFP/RFP-tagged protein markers and monoclonal antibodies) and imaging techniques, and imaging data collection, 2) Computational analysis of the phenotype image data, and 3) Development of research strategy that integrate quantitative phenotype analysis and simulation.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (109 results)

All 2010 2009 2008 2007 2006 2005 Other

All Journal Article (34 results) (of which Peer Reviewed: 24 results) Presentation (59 results) Book (12 results) Remarks (4 results)

  • [Journal Article] The Role of Protein Phosphatase 4 (PP4) in Regulating Microtubule Severing in the Caenorhabditis elegans Embryo.2009

    • Author(s)
      Sugimoto A. (6名中5番目)
    • Journal Title

      Genetics 181

      Pages: 933-943

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Clearance of germ granules in the soma2009

    • Author(s)
      Asako Sugimoto
    • Journal Title

      F1000 Biology Reports 2009 1:49

      Pages: 1-3

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 線虫における生殖顆粒の形成と配分2009

    • Author(s)
      花澤桃世
    • Journal Title

      蛋白質核酸酵素 54巻

      Pages: 2147-2152

    • Related Report
      2009 Annual Research Report
  • [Journal Article] A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex.2008

    • Author(s)
      Sugimoto A. (13名中6番目)
    • Journal Title

      Genes Dev 22

      Pages: 2385-2399

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficient production of monoclonal antibodies recognizing specific structures in Caenorhabditis elegans embryos using an antigen subtraction method2008

    • Author(s)
      Sugimoto A. (5名中5番目)
    • Journal Title

      Genes Cells 13

      Pages: 653-665

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Caenorhabditis elegans DDX-23, a homolog of yeast splicing factor PRP28, is required for the sperm-oocyte switch and differentiation of various cell types2008

    • Author(s)
      Konishi, T., Uodome, N., Sugimoto A.
    • Journal Title

      Dev Dyn 237

      Pages: 2367-2377

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components : SPDL-1 and the Rod/Zwilch/ZW1O complex2008

    • Author(s)
      Reto Gassmann
    • Journal Title

      Genes and Development 22

      Pages: 2385-2399

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Caenorhabditis elegans DDX-23, a homolog of yeast splicing factor PRP28, is required for the sperm-oocyte switch and differentiation of various cell types2008

    • Author(s)
      Takafumi Konishi
    • Journal Title

      Developmental Dynamics 237

      Pages: 2367-2377

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficient production of monoclonal antibodies recognizing specific structures in Caenorhabditis elegans embryos using an antigen subtraction method2008

    • Author(s)
      Kazumasa Takeda
    • Journal Title

      Genes to Cells 13

      Pages: 653-665

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Role of Protein Phosphatase 4 (PP4) in Regulating Microtubule Severing in the Caenorhabditis elegans Embryo.2008

    • Author(s)
      Xue Han
    • Journal Title

      Genetics (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans.2007

    • Author(s)
      Sugimoto A. (14名中13番目)
    • Journal Title

      Curr Biol 17

      Pages: 1555-1560

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] A system for measuring cell division patterns of early Caenorhabditis elegans embryos by using image processing and object tracking2007

    • Author(s)
      Hamahashi, S., Kitano, H., Onami, S.
    • Journal Title

      Systems and Computers in Japan 38(11)

      Pages: 12-24

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 線虫Caenorhabditis elegans初期胚の細胞分裂パターン計測システムのリコンフィギャラブルシステムによる高速化2007

    • Author(s)
      大浪修一(6名中5番目)
    • Journal Title

      電子情報通信学会論文誌D J90-D

      Pages: 2970-2980

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans2007

    • Author(s)
      Kimura, A., Onami, S.
    • Journal Title

      J. Cell Biol. 179

      Pages: 1347-1354

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] EGG-3 regulates cell-surface and cortex rearrangements during egg activation in Caenorhabditis elegans.2007

    • Author(s)
      Maruyama, R., A. Sugimoto, et. al.
    • Journal Title

      Current Biology 17

      Pages: 1555-1560

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A system for measuring cell division patterns of early Caenorhabditis elegans embryos by using image processing and object tracking.2007

    • Author(s)
      Hamahashi, S., Kitano, H., and Onami, S.
    • Journal Title

      Systems and Computers in Japan 38(11)

      Pages: 12-24

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 線虫Caenorhabditis elegans初期胚の細胞分裂パターン計測システムのリコンフィギャラブルシステムによる高速化2007

    • Author(s)
      福島知紀, 大浪修一, 他4名
    • Journal Title

      電子情報通信学会論文誌D J90-D

      Pages: 2970-2980

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Local cortical pulling-force repression switches centrosomal centration and posterior displacement in C. elegans2007

    • Author(s)
      Kimura, A., and Onami, S.
    • Journal Title

      The Journal of Cell Biology 179

      Pages: 1347-1354

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two phases of astral microtubule activity during cytokinesis in C. elegans embryos2006

    • Author(s)
      Motegi, F., Velarde, N.V., Piano, F., Sugimoto A.
    • Journal Title

      Dev. Cell 10

      Pages: 509-20

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential functioning of ECT-2/RhoGEF, RHO-1 and CDC-42 establishes cell polarity in C. elegans embryos2006

    • Author(s)
      Motegi, F., Sugimoto A.
    • Journal Title

      Nat Cell Biol 8

      Pages: 978-985

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 画像処理とオブジェクトトラッキングを用いた線虫の初期胚の細胞分裂パターン計測システム2006

    • Author(s)
      濱橋秀互, 北野宏明, 大浪修一
    • Journal Title

      電子情報通信学会論文誌D J89-D

      Pages: 1248-1259

    • NAID

      110007385841

    • Related Report
      2009 Final Research Report
  • [Journal Article] Genome-wide prediction of genetic interactions in a metazoan.2006

    • Author(s)
      Onami, S., Kitano, H.
    • Journal Title

      Bioessays 28

      Pages: 1087-1090

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential functioning of ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos.2006

    • Author(s)
      Motegi, F., Sugimoto, A.
    • Journal Title

      Nature Cell Biology 8

      Pages: 978-985

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Two Phases of Astral Microtubule Activity during Cytokinesis in C. elegans Embryos.2006

    • Author(s)
      Motegi, F., Velarde, N.V., Piano, F., Sugimoto, A.
    • Journal Title

      Developmental Cell 10

      Pages: 509-520

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 画像処理とオブジェクトトラッキングを用いた線虫の初期胚の細胞分裂パターン計測システム2006

    • Author(s)
      濱橋秀互, 北野宏明, 大浪修一
    • Journal Title

      電子情報通信学会論文誌 D, J89-D

      Pages: 1248-1259

    • NAID

      110007385841

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Genome-wide prediction of genetic interactions in a metazoan2006

    • Author(s)
      Onami, S., Kitano, H.
    • Journal Title

      Bioessays 28

      Pages: 1087-1090

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The C. elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.2005

    • Author(s)
      Furuya, M., Qadota, H., Chisholm, A.D., Sugimoto A.
    • Journal Title

      Dev Biol 286

      Pages: 452-463

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Objective measurement of spindle orientation in early Caenorhabditis elegans embryos.2005

    • Author(s)
      Hamahashi, S., Onami, S.
    • Journal Title

      Genome Inform 16

      Pages: 86-93

    • NAID

      130003997415

    • Related Report
      2009 Final Research Report 2005 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Detection of nuclei in 4D Nomarski DIC microscope images of early Caenorhabditis elegans embryos using local image entropy and object tracking.2005

    • Author(s)
      Hamahashi, S., Onami, S., Kitano, H.
    • Journal Title

      BMC Bioinformatics 6

      Pages: 125-125

    • Related Report
      2009 Final Research Report 2005 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computer simulations and image processing reveal length-dependent pulling force as the primary mechanism for C. elegans male pronuclear migration.2005

    • Author(s)
      Kimura, A., Onami, S.
    • Journal Title

      Dev Cell 8

      Pages: 765-75

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development.2005

    • Author(s)
      Sugimoto A. (9名中6番目)
    • Journal Title

      J Biol Chem 280

      Pages: 19689-94

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The C.elegans eyes absent ortholog EYA-1 is required for tissue differentiation and plays partially redundant roles with PAX-6.2005

    • Author(s)
      Furuya, M., Qadota, H., Chisholm, A.D., Sugimoto, A.
    • Journal Title

      Dev Biol 286

      Pages: 452-463

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Computer simulations and image processing reveal length-dependent pulling force as the primary mechanism for C.elegans male pronuclear migration.2005

    • Author(s)
      Kimura, A., Onami, S.
    • Journal Title

      Dev Cell 8

      Pages: 765-775

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development.2005

    • Author(s)
      Yanagi, K., Mizuno, T., Tsuyama, T., Tada, S., Iida, Y., Sugimoto, A., Eki, T., Enomoto, T., Hanaoka, F.
    • Journal Title

      J Biol Chem 280

      Pages: 19689-19694

    • Related Report
      2005 Annual Research Report
  • [Presentation] Assembly of germ granules in C.elegans2010

    • Author(s)
      Asako Sugimoto
    • Organizer
      Temasek Life Science Laboratory Seminar
    • Place of Presentation
      Singapore, Singapore
    • Year and Date
      2010-02-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 画像解析を活用した細胞・発生生物学研究の可能性2010

    • Author(s)
      Shuichi Onami
    • Organizer
      定量生物学の会第二回年会
    • Place of Presentation
      大阪府吹田市 大阪大学
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Genome-wide collection of quantitative information about cell division dynamics in RNAi-treated C. elegans embryo.2010

    • Author(s)
      Onami, S.
    • Organizer
      Sino-Japan Workshop, Systems Biology and Complex Diseases
    • Place of Presentation
      Shanghai, China.
    • Related Report
      2009 Final Research Report
  • [Presentation] Quantitative cell division dynamics information from early C.elegans embryos2009

    • Author(s)
      Koji Kyoda
    • Organizer
      The 20th International Conference on Genome Informatics
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] Live cell imaging and image-processing enable quantitative and computational analysis of the development2009

    • Author(s)
      Shuichi Onami
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 定量・計算解析による発生ダイナミクスの理解2009

    • Author(s)
      Shuichi Onami
    • Organizer
      日本機械学会第22回計算力学講演会CMD2009
    • Place of Presentation
      石川県金沢市 金沢大学
    • Year and Date
      2009-12-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] C.elegans PGL proteins mediate germ granule formation via their RNA-binding and self-aggregation abilities2009

    • Author(s)
      Momoyo Hanazawa
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜、神奈川
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Structure-function analysis of PGL-3 that play a crucial role in germ granule formation in C.elegans2009

    • Author(s)
      Masafumi Yonetani
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quantitative measurement and analysis of cell division dynamics information of early C.elegans embryos2009

    • Author(s)
      Koji Kyoda
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quantitative analysis of cell division pattern of C.elegans early RNAi embryo from time-lapse 2-D DIC microscope images in public database by using image processing2009

    • Author(s)
      Takuya Maeda
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Physical mechanism of cell rounding in C.elegans embryo2009

    • Author(s)
      Masashi Fujita
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      Yokohama, Kanagawa
    • Year and Date
      2009-12-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] 線虫C.elegans初期胚の細胞分裂ダイナミクスの定量解析2009

    • Author(s)
      Koji Kyoda
    • Organizer
      第19回日本数理生物学会大会
    • Place of Presentation
      東京都目黒区 東京大学
    • Year and Date
      2009-09-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Computational analysis of quantitative information of cell division dynamics of early embryos2009

    • Author(s)
      Koji Kyoda
    • Organizer
      17th International C.elegans Meeting
    • Place of Presentation
      Los Angels, California, USA
    • Year and Date
      2009-06-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Self-aggregation of PGL proteins plays a crucial role in P granule assembly.2009

    • Author(s)
      Hanazawa, M., M. Yonetani, A. Sugimoto.
    • Organizer
      17th International C. elegans Meeting.
    • Place of Presentation
      Los Angeles, California, USA.
    • Year and Date
      2009-06-25
    • Related Report
      2009 Final Research Report
  • [Presentation] Self-aggregation of PGL proteins plays a crucial role in P granule assembly2009

    • Author(s)
      Momoyo Hanazawa
    • Organizer
      17th International C.elegans Meeting
    • Place of Presentation
      Los Angels, California USA
    • Year and Date
      2009-06-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Structure-function analysis of PGL-3 that play a crucial role in P granule formation2009

    • Author(s)
      Masafumi Yonetani
    • Organizer
      17th International C.elegans Meeting
    • Place of Presentation
      Los Angels, California USA
    • Year and Date
      2009-06-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification of γ-tubulin complexes in C.elegans embryos2009

    • Author(s)
      Masahiro Terasawa
    • Organizer
      17th International C.elegans Meeting
    • Place of Presentation
      Los Angels, California, USA
    • Year and Date
      2009-06-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quantitative measurements and computer simulations of C.elegans embryonic cell morphology2009

    • Author(s)
      Masashi Fujita
    • Organizer
      17th International C.elegans Meeting
    • Place of Presentation
      Los Angels, California, USA
    • Year and Date
      2009-06-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Quantitative cell division dynamics analysis and prediction of the mechanism of development in C.elegans2009

    • Author(s)
      Shuichi Onami
    • Organizer
      The 9th NIBB-EMBL Symposium
    • Place of Presentation
      Okazaki Conference Center, Okazaki, Japan
    • Year and Date
      2009-04-21
    • Related Report
      2009 Annual Research Report
  • [Presentation] 細胞・発生生物学の超ペタフロップス級コンピュータへの展開2009

    • Author(s)
      Shuichi Onami
    • Organizer
      超ペタフロップス級コンピュータと実験生物学の連携による生命現象への挑戦
    • Place of Presentation
      理化学研究所横浜研究所
    • Year and Date
      2009-02-06
    • Related Report
      2008 Annual Research Report
  • [Presentation] Live cell imaging and image-processing enable quantitative and computational analysis of the development.2009

    • Author(s)
      Onami, S.
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      神戸
    • Related Report
      2009 Final Research Report
  • [Presentation] 定量・計算解析による発生ダイナミクスの理解2009

    • Author(s)
      大浪修一
    • Organizer
      日本機械学会計算力学講演会
    • Place of Presentation
      金沢大学角間キャンパス, 金沢.
    • Related Report
      2009 Final Research Report
  • [Presentation] 線虫C. elegans初期胚の細胞分裂ダイナミクスの定量解析2009

    • Author(s)
      京田耕司、足立絵瑠、倉持順子、島田久美子、大浪修一
    • Organizer
      第19回日本数理生物学会大会
    • Place of Presentation
      東京大学駒場キャンパス, 東京
    • Related Report
      2009 Final Research Report
  • [Presentation] Computational analysis of quantitative information of cell division dynamics of early embryos.2009

    • Author(s)
      Kyoda, K., Adachi, E., Shimada, K., Kuramochi, J., Onami, S.
    • Organizer
      17th International C. elegans Meeting.
    • Place of Presentation
      LA, USA
    • Related Report
      2009 Final Research Report
  • [Presentation] Quantitative cell division dynamics analysis and prediction of the mechanisms of development in C. elegans.2009

    • Author(s)
      Onami, S.
    • Organizer
      The 2nd RIKEN-University of Edinburgh Joint Workshop.
    • Place of Presentation
      British Embassy, Tokyo, Japan.
    • Related Report
      2009 Final Research Report
  • [Presentation] Quantitative cell division dynamics analysis and prediction of the mechanisms of development in C. elegans.2009

    • Author(s)
      Onami, S.
    • Organizer
      The 9th NIBB-EMBL Symposium, Functional Imaging from Atoms to Organisms.
    • Place of Presentation
      Okazaki Conference Center, Okazaki, Japan.
    • Related Report
      2009 Final Research Report
  • [Presentation] Quantitative cell division dynamics analysis and prediction of the mechanism of development in C. elegans.2009

    • Author(s)
      Onami, S.
    • Organizer
      International Symposium on System Biology and Proteomics in Biomedical Science
    • Place of Presentation
      Kolkata, India.
    • Related Report
      2009 Final Research Report
  • [Presentation] 細胞・発生生物学の超ペタフロップス級コンピュータへの展開2009

    • Author(s)
      大浪修一
    • Organizer
      超ペタフロップス級コンピュータと実験生物学の連携による生命現象への挑戦
    • Place of Presentation
      理化学研究所横浜研究所, 横浜
    • Related Report
      2009 Final Research Report
  • [Presentation] C. elegans RNAi 初期胚のタイムラプス顕微鏡画像からの画像処理システムを用いた細胞分裂パターンの大量測定2008

    • Author(s)
      Takuya Maeda
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 線虫初期胚の細胞形状を決定する力学的因子の計算機解析2008

    • Author(s)
      Masashi Fujita
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 培養細胞系を用いたC. elegans生殖顆粒構成因子 PGL-3 のドメイン解析2008

    • Author(s)
      Masafumi Yonetani
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] 線虫C. elegansの細胞分裂パターンの定量的計測と計算解析2008

    • Author(s)
      Koji Kyoda
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Assembly and positioning of mitotic spindles in early C. elegans embryos. BMB20082008

    • Author(s)
      Sugimoto, A.
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Related Report
      2009 Final Research Report
  • [Presentation] A quantitative and computational approach to dynamic nuclear positioning in C. elegans embryos2008

    • Author(s)
      Shuichi Onami
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      文部科学省ナショナルバイオリソースプロジェクト線虫・シンポジウム -Nematode: An ideal Model Organism for Functional Genomics-
    • Place of Presentation
      東京女子医科大学
    • Year and Date
      2008-11-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Reconstituting C. elegans Germ Granules in Mammalian Cells2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      The 17th CDB Meeting
    • Place of Presentation
      CDB, Kobe
    • Year and Date
      2008-10-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] Reconstituting C. elegans germ granules in mammalian cells.2008

    • Author(s)
      Sugimoto, A.
    • Organizer
      Cold Spring Harbor Laboratory meeting on Germ Cells.
    • Place of Presentation
      Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
    • Year and Date
      2008-10-03
    • Related Report
      2009 Final Research Report
  • [Presentation] Reconstituting C. elegans germ granules in mammalian cells2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      Cold Spring Harbor Laboratory meeting on Germ Cells
    • Place of Presentation
      Cold Spring Harbor, NY
    • Year and Date
      2008-10-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] 画像処理を用いた線虫初期発生における細胞分裂パターンの網羅的測定2008

    • Author(s)
      Takuya Maeda
    • Organizer
      第18回日本数理生物学会大会
    • Place of Presentation
      同志社大学
    • Year and Date
      2008-09-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans.2008

    • Author(s)
      Sugimoto, A.
    • Organizer
      Frontiers in Developmental Biology.
    • Place of Presentation
      Presqu'ile de Giens, Southern France.
    • Year and Date
      2008-09-14
    • Related Report
      2009 Final Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans.2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      Frontiers in Developmental Biology
    • Place of Presentation
      Presqu'ile de Giens, Southern France
    • Year and Date
      2008-09-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] 初期胚の構造と形態のダイナミクスに対する定量的計算科学的アプローチ2008

    • Author(s)
      Shuichi Onami
    • Organizer
      細胞・発生研究への数理科学的アプローチ-先端研究から探るアクションプラン-
    • Place of Presentation
      理化学研究所神戸研究所
    • Year and Date
      2008-09-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] 画像処理を活用した線虫C. elegans胚の定量的計算科学的解析2008

    • Author(s)
      Shuichi Onami
    • Organizer
      第3回 NIBB バイオイメージングフォーラム
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2008-09-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Quantitative and computational cell division pattern analysis of early embryos2008

    • Author(s)
      Shuichi Onami
    • Organizer
      C. elegans Genomics and Systems Biology Workshop
    • Place of Presentation
      Cambridge, MA, USA
    • Year and Date
      2008-07-24
    • Related Report
      2008 Annual Research Report
  • [Presentation] Computational analysis of quantitative cell division patterns of early embryos2008

    • Author(s)
      Koji Kyoda
    • Organizer
      C. elegans Development & Evolution Meeting 2008
    • Place of Presentation
      Madison, WI, USA
    • Year and Date
      2008-06-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] DDX-23, a DEAD-box protein, is involved in the sperm/oocyte switch2008

    • Author(s)
      Takafumi Konishi
    • Organizer
      The 3^<rd> East Asia C. elegans Meeting 2008
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2008-04-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Domain analysis of PGL-3, a core component of P granules, using cultured mammalian cells2008

    • Author(s)
      Masafumi Yonetani
    • Organizer
      The 3^<rd> East Asia C. elegans Meeting 2008
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2008-04-20
    • Related Report
      2008 Annual Research Report
  • [Presentation] Dissecting the structure and assembly of P granules in heterologous cells2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      The 3^<rd> East Asia. C.elegans Meeting 2008
    • Place of Presentation
      Shanghai,China
    • Year and Date
      2008-04-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Automatic measurement of nuclear dynamics in DIC microscope movies from public database2008

    • Author(s)
      Takuya Maeda
    • Organizer
      The 3rd East Asia C. elegans Meeting
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2008-04-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Dissecting the structure and assembly of C. elegans germ granules in heterologous cells.2008

    • Author(s)
      Sugimoto, A.
    • Organizer
      "RNA" Granules Meeting.
    • Place of Presentation
      Chevy Chase, Maryland, USA
    • Year and Date
      2008-04-02
    • Related Report
      2009 Final Research Report
  • [Presentation] Dissecting the structure and assembly of C. elegans germ granules in heterologous cells2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      "RNA" Granules Meeting
    • Place of Presentation
      Chevy Chase, Maryland
    • Year and Date
      2008-04-02
    • Related Report
      2008 Annual Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans.2008

    • Author(s)
      Sugimoto, A.
    • Organizer
      Swiss-Japan Joint Seminar.
    • Place of Presentation
      Arosa, Switzerland.
    • Year and Date
      2008-01-08
    • Related Report
      2009 Final Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans2008

    • Author(s)
      Asako Sugimoto
    • Organizer
      Swiss-Japan Joint Seminar
    • Place of Presentation
      Arosa, Switzerland
    • Year and Date
      2008-01-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] Structure and assembly of germ granules in C. elegans.2007

    • Author(s)
      Sugimoto, A.
    • Organizer
      Pasteur + CDB Joint Meeting.
    • Place of Presentation
      Paris, France.
    • Year and Date
      2007-11-29
    • Related Report
      2009 Final Research Report
  • [Presentation] Cellular dynamics in early C. elegans embryos2007

    • Author(s)
      Asako Sugimoto
    • Organizer
      Gordon Research Conferences
    • Place of Presentation
      Andover, USA
    • Year and Date
      2007-06-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cellular dynamics in early C. elegans embryos. Establishment of polarity in C. elegans 1-cell embryos.2007

    • Author(s)
      Sugimoto, A.
    • Organizer
      Gordon Research Conference "Developmental Biology"2007 Taiwan- Japan Bi-lateral Symposium.
    • Place of Presentation
      Andover, NH, USA, Taiwan.
    • Related Report
      2009 Final Research Report
  • [Presentation] 線虫発生過程のフェノーム解析2006

    • Author(s)
      杉本亜砂子
    • Organizer
      日本遺伝学会第78回大会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2006-09-25
    • Related Report
      2009 Final Research Report
  • [Presentation] Profiling and cluster analysis of developmental RNAi phenotypes in C. elegans.2005

    • Author(s)
      Sugimoto, A.
    • Organizer
      Gordon Research Conference "Developmental Biology"
    • Place of Presentation
      Andover, NH
    • Year and Date
      2005-06-20
    • Related Report
      2009 Final Research Report
  • [Presentation] 線虫発生過程のフェノーム解析2005

    • Author(s)
      杉本亜砂子
    • Organizer
      表現型をどう「表現」するか?日本分子生物学会年会
    • Place of Presentation
      福岡
    • Related Report
      2009 Final Research Report
  • [Book] 蛋白質核酸酵素(線虫における生殖顆粒の形成と配分, 54)2009

    • Author(s)
      花澤桃世、米谷匡史, 杉本亜砂子
    • Publisher
      共立出版
    • Related Report
      2009 Final Research Report
  • [Book] 文部科学省科学研究費特定領域研究「ゲノム4領域」(ゲノムに書かれた発生プログラムを読み解く--線虫をモデル系として. ゲノムは何をどのように決めているのか? 生命システムの理解に向けて)2007

    • Author(s)
      杉本亜砂子
    • Publisher
      クパブロ
    • Related Report
      2009 Final Research Report
  • [Book] 比較ゲノム学から読み解く生命システム(線虫の比較ゲノム)2007

    • Author(s)
      杉本亜砂子
    • Publisher
      秀潤社
    • Related Report
      2009 Final Research Report
  • [Book] 実験医学(体系的表現型解析で探る線虫の発生機構, 25)2007

    • Author(s)
      杉本亜砂子
    • Related Report
      2009 Final Research Report
  • [Book] DBRF-MEGN method: An algorithm for inferring gene regulatory networks from large-scale gene expression profiles.2007

    • Author(s)
      Onami, S., Kyoda, K.
    • Publisher
      Humana Press
    • Related Report
      2009 Final Research Report
  • [Book] DBRF-MEGN method: an algorithm for inferring gene regulatory networks from large-scale gene expression profiles, "Introduction to Systems Biology"2007

    • Author(s)
      Kyoda, K., and Onami, S.
    • Total Pages
      14
    • Publisher
      Humana Press
    • Related Report
      2007 Annual Research Report
  • [Book] 線虫の比較ゲノム, 「比較ゲノム学から読み解く生命システム」2007

    • Author(s)
      杉本 亜砂子
    • Total Pages
      6
    • Publisher
      秀潤社
    • Related Report
      2007 Annual Research Report
  • [Book] in vivoイメージングのためのプローブ:線虫, 「実験がうまくいく蛍光・発光試薬の選び方と使い方」2007

    • Author(s)
      小西隆文, 杉本亜砂子
    • Total Pages
      8
    • Publisher
      羊土社
    • Related Report
      2007 Annual Research Report
  • [Book] 蛋白質核酸酵素(コンピュータシミュレーションを利用した核の配置のダイナミクス解析, 51)2006

    • Author(s)
      木村暁、大浪修一
    • Publisher
      共立出版
    • Related Report
      2009 Final Research Report
  • [Book] 蛋白質核酸酵素(線虫ゲノムの体系的発現・機能解析, 50)2005

    • Author(s)
      杉本亜砂子、小原雄治
    • Publisher
      共立出版
    • Related Report
      2009 Final Research Report
  • [Book] RNA工学の最前線 線虫(C. elegans)におけるRNAiの応用2005

    • Author(s)
      飯田直子、杉本亜砂子
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Final Research Report
  • [Book] 蛋白質核酸酵素(発生のシステムバイオロジー, 50)2005

    • Author(s)
      大浪修一、北野宏明
    • Publisher
      共立出版
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.cdb.riken.jp/dge/KTmAbDB/KTtop.html

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://so.gsc.riken.jp/cdd/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.cdb.riken.jp/dge/KTmAbDB/KTtop.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.cdb.riken.jp/dge/KTmAbDB/Kttop.html

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2005-04-01   Modified: 2018-03-28  

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