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Exercise and nutritional prescription aiming at preventing functional deterioration of skeletal muscle induced by immobilization

Research Project

Project/Area Number 17300221
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied health science
Research InstitutionNational Institute of Fitness and Sports in Kanoya

Principal Investigator

HAMAOKA Takafumi  National Institute of Fitness and Sports in Kanoya, 体育学部, 教授 (70266518)

Co-Investigator(Kenkyū-buntansha) 勝村 俊仁  東京医科大学, 医学部, 教授 (80214352)
村瀬 訓生  東京医科大学, 医学部, 講師 (10317894)
長田 卓也  東京医科大学, 医学部, 講師 (60297281)
木目 良太郎  東京医科大学, 医学部, 講師 (90366120)
江崎 和希  東京医科大学, 医学部, 研究員 (90375478)
Co-Investigator(Renkei-kenkyūsha) KATSUMURA Toshihito  東京医科大学, 医学部, 教授 (80214352)
MURASE Norio  東京医科大学, 医学部, 講師 (10317894)
OSADA Takuya  東京医科大学, 医学部, 講師 (60297281)
KIME Ryoutaro  東京医科大学, 医学部, 講師 (90366120)
ESAKI Kazuki  東京医科大学, 医学部, 研究員 (90375478)
Project Period (FY) 2005 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥10,760,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2008: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2007: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2006: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2005: ¥3,000,000 (Direct Cost: ¥3,000,000)
Keywords不活動 / 筋力 / 持久力 / トレーニング / 筋血流 / 筋不動化 / 筋有酸素能 / 筋力トレーニング / 持久トレーニング / 運動処方 / アミノ酸投与 / 運動トレーニング / 身体不活動 / 筋エネルギー代謝 / 血管内皮機能
Research Abstract

不活動に伴う筋力, 筋代謝能および血流の低下の程度と、運動トレーニングが各指標の低下(悪化)予防に有効か否かを検討した。健常成人男性42名を対象として, 21日間の上肢ギプス固定を行った。固定期間中に, トレーニングを行わない群と週2回の筋力(握力の70%の運動を10回)+持久トレーニング群(動的グリップ運動を疲労困憊まで)を設けた。測定の結果, 各指標はギプス固定により低下し, トレーニングによりその低下が抑制できた。

Report

(5 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • 2005 Annual Research Report
  • Research Products

    (38 results)

All 2009 2008 2007 2006 2005 Other

All Journal Article (22 results) (of which Peer Reviewed: 12 results) Presentation (11 results) Book (5 results)

  • [Journal Article] Local increase in trapezius muscle oxygenation during and after acupuncture.2009

    • Author(s)
      M. Ohkubo, T. Hamaoka, M. Niwayama, N. Murase, T. Osada, R. Kime, Y. Kurosawa, A. Sakamoto, T. Katsumura.
    • Journal Title

      Dyn. Med. 8

      Pages: 2-2

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Local increase in trapezius muscle oxygenation during and after acupuncture2009

    • Author(s)
      M. Ohkubo. T. Hamaoka, M. Niwayama, N. Murase, T. Osada, R. Kime, Y. Kurosawa, A. Sakamoto, T. Katsumura
    • Journal Title

      Dyn. Med. 8:2

      Pages: 1-8

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-volume muscle endurance training prevents decrease inmuscle oxidative and endurance function during 21-day forearmimmobilization.2009

    • Author(s)
      T. Homma, T. Hamaoka, N. Murase, T. Osada, M. Murakami, Y. Kurosawa, A. Kitahara, S. Ichimura, K. Yashiro, T. Ratsumura
    • Journal Title

      Acta. Physiologica (印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-volume muscular endurance and strength training during 3-week forearm immobilization was effective in preventing functional deterioration2008

    • Author(s)
      M. Matsumura, C. Ueda, K. Shiroishi, K. Esaki, F. Ohmori, K. Yamaguchi, S. Ichimura, Y. Kurosawa, R. Kime, T. Osada, N. Murase, T. Katsumura, A. Hoshika and T. Hamaoka
    • Journal Title

      Dyn. Med. 7

      Pages: 1-1

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] スポーツ・健康増進と近赤外分光2008

    • Author(s)
      浜岡隆文
    • Journal Title

      光と医・食・農 光産業技術振興協会

      Pages: 39-44

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 地域在宅高齢者における「閉じこもり」と身体活動状況および体力2008

    • Author(s)
      恒吉玲代, 永山寛, 涌井佐和, 浜岡隆文, 齋藤和人, 前田明, 図子浩二, 井上尚武, 和田智仁, 隅野美砂輝, 荻田太, 吉武裕
    • Journal Title

      体力科学 57(4)

      Pages: 433-442

    • NAID

      110006873848

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 筋力増強のための機能性食品2008

    • Author(s)
      浜岡隆文, 江崎和希, 黒澤裕子
    • Journal Title

      Functional Food 2(3)

      Pages: 268-274

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Low-volume muscular endurance and strength training during 3-week forearm immobilization was effective in preventing functional deterioration2008

    • Author(s)
      Matsumura, Mら
    • Journal Title

      Dynamic Medicine 7:1

      Pages: 1-8

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Near-infrared spectroscopy/imaging for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased humans2007

    • Author(s)
      T. Hamaoka, K. McCully, V. Quaresima, K. Yamamoto, and B. Chance.
    • Journal Title

      J. Biomed. Opt. 12(6)

      Pages: 62105-62120

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Near-infrared spectroscopy/imaging for monitoring muscle oxygenation and oxidative metabolism in healthy and diseased hnmans2007

    • Author(s)
      Hamaoka, Tら
    • Journal Title

      Journal of Biomedical Optics 12:6

      Pages: 62105-62116

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impaired muscle oxygen metabolism in uremic children : improved after renal transplantation2006

    • Author(s)
      N. Matsumoto, S. Ichimura, T. Hamaoka, T. Osada, M. Hattori, and S. Miyakawa.
    • Journal Title

      Am J Kidney Dis 48(3)

      Pages: 473-80

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Simulation of Mb/Hb in nirs and oxygen gradient in the human and canine skeletal muscles using H-NMR and NIRS2006

    • Author(s)
      S. Nioka, D.J. Wang, J. Im, T. Hamaoka, Z.J. Wang, J.S. Leigh, B. Chance.
    • Journal Title

      Adv Exp Med Biol 578

      Pages: 223-228

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Oxygenation and energetics of the human skeletal muscle during elevated energy demand2006

    • Author(s)
      T. Hamaoka, Y. Kurosawa, T. Osada, T. Sako, H. Hiroyuki, S. Nishio, N. Murase, and T. Katsumura.
    • Journal Title

      J. Exerc. Sci 16

      Pages: 13-23

    • NAID

      120006789224

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Change of forearm muscle oxygen consumption in pediatrie kidney transplant patients.2006

    • Author(s)
      S.Miyakawaら
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med. 55 Supple.

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Blood flow after contraction of short duration reaches its peak by 3rd cardiac cycle.2006

    • Author(s)
      F.Ohmoriら
    • Journal Title

      Jpn. J. Phys. Fitness Sports Med. 55 Supple.

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Age and activity status affect muscle reoxygenation time after maximal cycling exercise.2006

    • Author(s)
      S.Ichimuraら
    • Journal Title

      Med. Sci. Sports Exerc. 38(7)

      Pages: 2006-2006

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Contribution of oxidative metabolism using intramuscular 02 to total ATP production during forearm isometric exercise at varying intensities.2006

    • Author(s)
      N.Kimuraら
    • Journal Title

      The Tohoku Journal of Experimental Medicine. 208(4)

      Pages: 307-320

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Impaired muscle oxygen metabolism in uremic children : improved after renal transplantation.2006

    • Author(s)
      N.Matsumotoら
    • Journal Title

      Am J Kidney Dis. 48(3)

      Pages: 473-480

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Simulation of Mb/Hb in nirs and Oxygen gradient in the human and canine skeletal muscles using H-NMR and NIRS.2006

    • Author(s)
      S.Niokaら
    • Journal Title

      Adv Exp Med Biol. 578

      Pages: 223-228

    • Related Report
      2006 Annual Research Report
  • [Journal Article] スポーツ医学・健康増進と光技術2006

    • Author(s)
      浜岡隆文
    • Journal Title

      オプトロニクス 25(291):

      Pages: 127-130

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 筋の酸素化状態と筋代謝2005

    • Author(s)
      浜岡隆文, 木目良太郎
    • Journal Title

      体育の科学 55(12)

      Pages: 918-924

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Low-volume muscle endurance training prevents decrease in muscle oxidative and endurance function during 21-day forearm immobilization

    • Author(s)
      T. Homma, T. Hamaoka, N. Murase, T. Osada, M. Murakami, Y. Kurosawa, A. Kitahara, S. Ichimura, , K. Yashiro, T. Katsumura
    • Journal Title

      Acta. Physiologica (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] 近赤外線分光法を用いた健常筋の機能評価(シンポジウム)2008

    • Author(s)
      浜岡隆文
    • Organizer
      医用近赤外線分光法研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-10-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] 地域在住高齢者の身体活動状況 -中等強度の身体活動時間と1日の歩数-2008

    • Author(s)
      東恩納玲代, 永山寛, 齋藤和人, 浜岡隆文
    • Organizer
      日本生涯スポーツ学会
    • Place of Presentation
      那覇
    • Year and Date
      2008-10-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] 水中運動時におけるグリセリン摂取の影響2008

    • Author(s)
      矢野琢也, 前田明, 荻田太, 浜岡隆文
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      別府
    • Year and Date
      2008-09-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Low-volume grip exercise training prevents immobilization-induced decrease in peak blood flow during exhaustive gripexercise2008

    • Author(s)
      Ohmori F, Shiroishi K., Hamaoka T., Osada T., Murase N., Kime R., Kurosawa Y., Ichimura S., HommaT., Mori M., Esaki K., Yamaguchi K., Katsumura T
    • Organizer
      European College of Sport Science12th European College of Sport Science
    • Place of Presentation
      Estoril
    • Year and Date
      2008-07-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Low-volume grip exercise training prevents immobilization-induced decrease in peak blood flow during exhaustive grip exercise"2008

    • Author(s)
      大森芙美子
    • Organizer
      第13回ヨーロッパスポーツ 科学学会
    • Place of Presentation
      エストリル
    • Related Report
      2008 Final Research Report
  • [Presentation] 筋循環・代謝研究における近赤外分光法の有用性と限界2007

    • Author(s)
      浜岡隆文
    • Organizer
      第14医用近赤外線分光法研究会
    • Place of Presentation
      松本
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 筋不活動による骨格筋酸素供給・消費の変化2007

    • Author(s)
      浜岡隆文
    • Organizer
      第12回酸素ダイナミクス研究会
    • Place of Presentation
      広島
    • Related Report
      2008 Final Research Report
  • [Presentation] Low-volume-combined exercise training prevents immobilization-induced decrease in muscle function and blood flow response2007

    • Author(s)
      大森芙美子
    • Organizer
      第12回ヨーロッパスポーツ科学学会
    • Place of Presentation
      ユバスキュラ
    • Related Report
      2008 Final Research Report
  • [Presentation] Prevention of immobilization-induced muscle dysfunction using low volume exercise training and branched chain amino acids intake2007

    • Author(s)
      山口国子
    • Organizer
      第12回ヨーロッパスポーツ科学学会
    • Place of Presentation
      ユバスキュラ
    • Related Report
      2008 Final Research Report
  • [Presentation] 近赤外分光法の正しい使い方について2006

    • Author(s)
      浜岡隆文
    • Organizer
      第20回呼吸研究会
    • Place of Presentation
      神戸
    • Related Report
      2008 Final Research Report
  • [Presentation] The changes in brain and muscle metabolism by the combination of caffeine supplementation and low volume exercise training2006

    • Author(s)
      Esaki, K., Yashiro, K., Sako, T., Yoshitake, Y., Ohkubo, M., Kuwamori, M., Yamaguchi, K., Kinugasa, T., Takemasa, T., Hamaoka, T.
    • Organizer
      第11回ヨーロッパスポーツ科学会議
    • Place of Presentation
      ローザンヌ
    • Related Report
      2008 Final Research Report
  • [Book] スポーツ・健康増進と近赤外分光 光と医・食・農2008

    • Author(s)
      浜岡隆文
    • Publisher
      光産業技術振興協会
    • Related Report
      2008 Final Research Report
  • [Book] 運動およびアミノ酸摂取による筋機能低下の予防2007

    • Author(s)
      浜岡隆文
    • Publisher
      アサヒビール学術振興財団
    • Related Report
      2008 Final Research Report
  • [Book] スポーツ医学・健康増進と光技術 光センシング技術資料集 -バイオフォトニクスを中心に-2006

    • Author(s)
      浜岡隆文
    • Publisher
      オプトロニクス社
    • Related Report
      2008 Final Research Report
  • [Book] コーヒーと運動時筋代謝 コーヒーの科学と機能2006

    • Author(s)
      浜岡隆文, 江崎和希(グュエン・ヴァン・チュエン、石川俊次 共編)
    • Publisher
      アイ・ケイコーポレーション
    • Related Report
      2008 Final Research Report
  • [Book] 食肉に含まれる機能性成分(L-カルニチン)摂取による成人女性のエネルギー代謝に及ぼす影響2005

    • Author(s)
      佐古隆之, 浜岡隆文, 中出浩二
    • Publisher
      平成17年度食肉に関する助成研究調査成果報告書
    • Related Report
      2008 Final Research Report

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Published: 2005-04-01   Modified: 2016-04-21  

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