Academic Systematization of Separation Analysis Based on Phase Separation Multiphase Flow and Its Practical Technical Improvements
| Project/Area Number |
17H03083
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Doshisha University |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2020: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2019: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2018: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2017: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Keywords | 相分離混相流 / 学術的体系化 / 技術的体系化 / クロマトグラフィー / 微小空間 / 抽出 / 微小領域 / 相分離 / 液液界面 / 管径方向分配流 / 分離回収 / 分離 / 二相分離混相流 / PEG/デキストラン / 分離分析 / 動的液-液界面 |
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| Outline of Final Research Achievements |
Capillary chromatography, which utilizes two liquid phase flows generated by "phase-separated multiphase flow" as a mobile phase and a pseudo-stationary phase, is based on an original idea and has not been reported elsewhere. Since it does not require special machining of the capillary or the application of voltage, it can realize drastic simplification and simplification of equipment and operation compared to conventional methods. Therefore, it is of great significance to improve capillary chromatography using "phase separation multiphase flow" from the academic research level to a general-purpose system with marketability by accumulating research. In this research, we will develop capillary chromatography based on "phase separation multi-phase flow", which has a great impact both academically and socially.
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| Academic Significance and Societal Importance of the Research Achievements |
微小領域の流れとして，層流，電気浸透流，非混和混相流がある．二相分離混合溶液を用いて，それらとは異なる流れ，相分離混相流が見出された．相分離混相流には，さまざまな動的液-液界面が観察されるが，環状流は，相分離混相流によって初めて微小領域内に創出されており，興味深い流れである．その創出メカニズムを学術的視点から掘り下げた．さらにTRDFを利用して，クロマトグラフィー，抽出，混合，化学反応に関わる技術開発を行い，技術的体系化を試みた．今後，学術面および技術面において，幅広い研究・開発が行われることが期待される．
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Report
(5 results)
Research Products
(12 results)
