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Investigation for the cause of postpressure sores infections focusing on the change in skin resident flora, and study on preventive and palliative care based on the results for this investigation

Research Project

Project/Area Number 17H04428
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Fundamental nursing
Research InstitutionKanazawa University

Principal Investigator

Okamoto Shigefumi  金沢大学, 保健学系, 教授 (50311759)

Co-Investigator(Kenkyū-buntansha) 須釜 淳子  金沢大学, 新学術創成研究機構, 教授 (00203307)
杉谷 加代  金沢大学, 保健学系, 助教 (20162258)
大貝 和裕  金沢大学, AIホスピタル・マクロシグナルダイナミクス研究開発センター, 准教授 (40706983)
Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2020: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2019: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2018: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Keywordsマイクロバイオーム / 褥瘡後感染症 / 寝たきり高齢者 / Staphylococcus / 皮膚 / Staphylococcus属細菌 / 中鎖脂肪酸 / 看護学 / 褥瘡後感染 / 皮膚常在細菌叢 / 感染制御 / 緩和ケア / 褥瘡 / 細菌 / 脂質 / 予防緩和ケア / 皮膚常在菌叢
Outline of Final Research Achievements

Skin microbiome is formed on all round of the skin; however, it was unknown whether change skin microbiome composition in the bed ridden elderly is associated with onset of post-pressure ulcer infections. In our study, the new method for harvesting skin microbiome easily and exactly was developed, and we examined the above question by using our new method. We found that the composition of skin microbiome in the elderly is different from those in healthy people. Specially, The relative range of Genus Staphylococcus, Genus Corynebacterium, and Enterobacteriaceae was increased in the skin microbiome of bed-ridden elderly. Furthermore, a higher rate of Staphylococcus species on the healed site were found.

Academic Significance and Societal Importance of the Research Achievements

わが国における超高齢化社会の急速な進展により、高齢者のQuality of Life (QOL)の向上の実現が重要な問題となりつつある。特に寝たきり高齢者のQOL向上を考える際、褥瘡による皮膚感染症の原因を明らかにし、科学的根拠に基づく緩和および予防を見出すことは大変重要な問題であると考える。
我々は、その問題解決のために本研究課題を取り組んだものである。褥瘡の悪化、再発、褥瘡後感染症の発症に、寝たきり高齢者の皮膚細菌叢の構成変化が関連し、特にStaphylococcus属細菌の存在比率の増加が上記発症の原因とある可能性を示唆した。この成果は褥瘡後感染症発症予防法の確立に重要な情報となりうる。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (55 results)

All 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (18 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 16 results,  Open Access: 13 results) Presentation (33 results) (of which Int'l Joint Research: 7 results,  Invited: 10 results) Book (2 results) Remarks (1 results)

  • [Int'l Joint Research] ヤウンデ第一大学(カメルーン)

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Amplicon-based skin microbiome profiles collected by tape stripping with different adhesive film dressings: a comparative study2021

    • Author(s)
      Ogai Kazuhiro、Shibata Kana、Takahashi Natsuki、Ogura Kohei、Okamoto Shigefumi、Sugama Junko
    • Journal Title

      BMC Microbiology

      Volume: 21 Issue: 1 Pages: 54-54

    • DOI

      10.1186/s12866-021-02122-4

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparative genome analysis of three Group A Streptococcus dysgalactiae subsp. equisimilis strains isolated in Japan2021

    • Author(s)
      Ishihara Haruka、Ogura Kohei、Nguyen Van An、Miyohi-Akiyama Tohru、Okamoto Shigefumi、Takemoto Norihiko
    • Journal Title

      Journal of Medical Microbiology

      Volume: 70 Issue: 3 Pages: 1322-1322

    • DOI

      10.1099/jmm.0.001322

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distinct Skin Microbiome and Skin Physiological Functions Between Bedridden Older Patients and Healthy People: A Single-Center Study in Japan2020

    • Author(s)
      Nagase Satoshi、Ogai Kazuhiro、Urai Tamae、Shibata Kana、Matsubara Emi、Mukai Kanae、Matsue Miki、Mori Yumiko、Aoki Miku、Arisandi Defa、Sugama Junko、Okamoto Shigefumi
    • Journal Title

      Frontiers in Medicine

      Volume: 7 Pages: 101-101

    • DOI

      10.3389/fmed.2020.00101

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Skin Physiology and its Microbiome as Factors Associated with the Recurrence of Pressure Injuries2020

    • Author(s)
      Shibata Kana、Ogai Kazuhiro、Ogura Kohei、Urai Tamae、Aoki Miku、Arisandi Defa、Takahashi Natsuki、Okamoto Shigefumi、Sanada Hiromi、Sugama Junko
    • Journal Title

      Biological Research For Nursing

      Volume: 23 Issue: 1 Pages: 75-81

    • DOI

      10.1177/1099800420941100

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Stability of Skin Microbiome at Sacral Regions of Healthy Young Adults, Ambulatory Older Adults, and Bedridden Older Patients After 2 Years2020

    • Author(s)
      Ogai Kazuhiro、Ogura Kohei、Ohgi Nozomi、Park Seohui、Aoki Miku、Urai Tamae、Nagase Satoshi、Okamoto Shigefumi、Sugama Junko
    • Journal Title

      Biological Research For Nursing

      Volume: 23 Issue: 1 Pages: 82-90

    • DOI

      10.1177/1099800420941151

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exploring the Risk Factors for the Development of Recurrent Pressure Ulcer in Elderly Patients: A Prospective Observational Study2020

    • Author(s)
      Defa Arisandi, Kazuhiro Ogai, Tamae Urai, Miku Aoki, Takeo Minematsu, Shigefumi Okamoto, Hiromi Sanada, Toshio Nakatani, Junko Sugama
    • Journal Title

      Journal of Wound Care

      Volume: 29 Issue: Sup4 Pages: 14-24

    • DOI

      10.12968/jowc.2020.29.sup4.s14

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Impact of Gut Microbiome on Hypertensive Patients With Low-Salt Intake: Shika Study Results2020

    • Author(s)
      Nagase Satoshi、Karashima Shigehiro、Tsujiguchi Hiromasa、Tsuboi Hirohito、Miyagi Sakae、Kometani Mitsuhiro、Aono Daisuke、Higashitani Takuya、Demura Masashi、Sakakibara Hiroyuki、Yoshida Akihiro、Hara Akinori、Nakamura Hiroyuki、Takeda Yoshiyu、Nambo Hidetaka、Yoneda Takashi、Okamoto Shigefumi
    • Journal Title

      Frontiers in Medicine

      Volume: 7 Pages: 475-475

    • DOI

      10.3389/fmed.2020.00475

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Novel Hyaluronate Lyase Involved in Pathogenicity of Streptococcus dysgalactiae subsp. equisimilis2020

    • Author(s)
      Nguyen VA, Ogura K, Matsue M, Takemoto N, Mukai K, Nakajima Y, Hoang TL, Iwata Y, Sakai N, Wada T, Hashimoto W, Okamoto S, Ichimura H.
    • Journal Title

      Front Microbiol

      Volume: 11 Pages: 552418-552418

    • DOI

      10.3389/fmicb.2020.552418

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pathogenicity Characterization of Prevalent-Type Streptococcus dysgalactiae subsp. equisimilis Strains2020

    • Author(s)
      Matsue Miki、Ogura Kohei、Sugiyama Hironori、Miyoshi-Akiyama Tohru、Takemori-Sakai Yukiko、Iwata Yasunori、Wada Takashi、Okamoto Shigefumi
    • Journal Title

      Frontiers in Microbiology

      Volume: 11 Pages: 97-97

    • DOI

      10.3389/fmicb.2020.00097

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Relationship between oral conditions and the gut microbiome in healthy adults in Ishikawa prefecture, Japan2020

    • Author(s)
      Nagase S, Kotani Y, Nakamura M, Matsuoka A, Okamoto S.
    • Journal Title

      Journal of Wellness and Health Care

      Volume: 43 Pages: 1-10

    • NAID

      120006782535

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Measuring the Antimicrobial Activity of Lauric Acid against Various Bacteria in Human Gut Microbiota Using a New Method2019

    • Author(s)
      Matsue Miki、Mori Yumiko、Nagase Satoshi、Sugiyama Yuta、Hirano Rika、Ogai Kazuhiro、Ogura Kohei、Kurihara Shin、Okamoto Shigefumi
    • Journal Title

      Cell Transplantation

      Volume: 28 Issue: 12 Pages: 1528-1541

    • DOI

      10.1177/0963689719881366

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prevalence and genomic characterization of Group A Streptococcus dysgalactiae subsp. equisimilis isolated from patients with invasive infections in Toyama prefecture, Japan2019

    • Author(s)
      Ishihara Haruka、Ogura Kohei、Miyoshi‐Akiyama Tohru、Nakamura Masahiko、Kaya Hiroyasu、Okamoto Shigefumi
    • Journal Title

      Microbiology and Immunology

      Volume: 64 Issue: 2 Pages: 113-122

    • DOI

      10.1111/1348-0421.12760

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Food bolus‐forming ability predicts incidence of aspiration pneumonia in nursing home older adults: A prospective observational study2019

    • Author(s)
      Hase Takashi、Miura Yuka、Nakagami Gojiro、Okamoto Shigefumi、Sanada Hiromi、Sugama Junko
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 1 Pages: 53-60

    • DOI

      10.1111/joor.12861

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 寝たきり高齢者における皮膚常在細菌叢の特徴と褥瘡後感染症発症ととの関連性―マイクロバイオーム解析からみえたこと―2019

    • Author(s)
      岡本成史
    • Journal Title

      地域ケアリング

      Volume: 21 Pages: 93-98

    • Related Report
      2019 Annual Research Report
  • [Journal Article] A Comparison of Techniques for Collecting Skin Microbiome Samples: Swabbing Versus Tape-Stripping2018

    • Author(s)
      Ogai Kazuhiro、Nagase Satoshi、Mukai Kanae、Iuchi Terumi、Mori Yumiko、Matsue Miki、Sugitani Kayo、Sugama Junko、Okamoto Shigefumi
    • Journal Title

      Frontiers in Microbiology

      Volume: 9 Pages: 2362-2362

    • DOI

      10.3389/fmicb.2018.02362

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pathogenic mechanisms of invasive group A Streptococcus (GAS) infections by influenza virus-GAS superinfection2018

    • Author(s)
      Okamoto Shigefumi、Nagase Satoshi
    • Journal Title

      Microbiol. Immunol.

      Volume: 62 Issue: 3 Pages: 141-149

    • DOI

      10.1111/1348-0421.12577

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of antimicrobial spectrum and mechanisms of organic virgin coconut oil and lauric acid against bacteria2017

    • Author(s)
      Nagase S, Matsue M, Mori Y, Honda-Ogawa M, Sugitani K, Sumitomo T, Nakata M, Kawabata S, Okamoto S
    • Journal Title

      Journal of Wellness and Health Care

      Volume: 41 Pages: 87-95

    • NAID

      120006364227

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 寝たきり高齢者における皮膚常在細菌叢構成の変化2017

    • Author(s)
      岡本成史,大貝和裕,須釜淳子
    • Journal Title

      BIO Clinica

      Volume: 32 Pages: 1300-1307

    • Related Report
      2017 Annual Research Report
  • [Presentation] in vitro ならびに in vivo において臨床分離大腸菌の増殖活性の指標となり得るアミノ酸の検索2021

    • Author(s)
      米澤茜音, 松榮美希, 水谷明日香, 小林正和, 大畑周星, 村中由佳, 水澤絵里, 巻秀樹, 川井恵一, 岡本成史
    • Organizer
      第94回日本細菌学会総会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Hyaluronate lyase involved in nutrient acquisition and pathogenicity of Streptococcus dysgalactiae2021

    • Author(s)
      An Van Nguyen, Kohei Ogura, Miki Matsue, Norihiko Takemoto, Wataru Hashimoto, Shigefumi Okamoto, Hiroshi Ichimura
    • Organizer
      第94回日本細菌学会総会学術集会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 国内外流行型Streptococcus dysgalactiae subsp. equisimilis の病原性解析2021

    • Author(s)
      松榮美希, 小倉康平, 秋山徹, 和田隆志, 岡本成史
    • Organizer
      第94回日本細菌学会総会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 寝たきり高齢者の皮膚にみられるディスバイオーシス2021

    • Author(s)
      大貝和裕, 長瀬賢史, 須釜淳子, 岡本成史
    • Organizer
      第94回日本細菌学会総会学術集会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] Distinct skin microbiome and skin physiological functions between bedridden older patients and healthy people: A single-center study in Japan.2020

    • Author(s)
      Shigefumi Okamoto
    • Organizer
      11th International Conference on Skin Aging and Challenges
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] A new measuring method for antimicrobial activity of lauric acid against various human gut microbes2020

    • Author(s)
      松榮美希,森裕美子,長瀬賢史,小倉康平,大貝和裕,杉山友太,平野里佳,栗原 新,岡本成史
    • Organizer
      第93回日本細菌学会総会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 寝たきり高齢者における皮膚細菌叢の変化と褥瘡後感染の発症への影響2020

    • Author(s)
      長瀬賢史,大貝和裕,浦井珠恵,柴田佳奈,向井加奈恵,松榮美希,青木未来,Defa Alsandi,須釜淳子,岡本成史
    • Organizer
      第93回日本細菌学会総会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 流行型 Streptococcus dysgalactiae subsp. equisimilis の病原性解析2020

    • Author(s)
      松榮美希,小倉康平,秋山徹,岡本成史
    • Organizer
      第93回日本細菌学会総会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] レンサ球菌ー多彩な細菌種と病原性ー2020

    • Author(s)
      岡本成史
    • Organizer
      第31回日本臨床微生物学会総会学術集会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 寝たきり高齢者における皮膚細菌叢の変化と褥瘡後感染の発症への影響2019

    • Author(s)
      長瀬賢史, 大貝和裕, 浦井珠恵, 柴田佳奈, 松原恵美, 向井加奈恵, 松榮美希, 森裕美子, 青木未来, Defa Alsandi, 須釜淳子, 岡本成史.
    • Organizer
      第102回日本細菌学会関東支部総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 侵襲性レンサ球菌感染症患者から単離されたA群 Streptococcus dysgalactiae subsp. equisimilis の全ゲノム解析.2019

    • Author(s)
      石原春香、彼谷裕康、岡本成史
    • Organizer
      第93回日本感染症学会総会・学術講演会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 医療用テープドレッシングを用いた皮膚常在細菌叢の採取方法の検討2019

    • Author(s)
      岡本成史, 長瀬賢史, 大貝和裕, 向井加奈恵, 松榮美希, 須釜淳子
    • Organizer
      第102回日本細菌学会関東支部総会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 口腔状態の変化に伴う口腔・腸内細菌叢の細菌構成変化の可能性2019

    • Author(s)
      松岡礼華、長瀬賢史、小谷勇介、中村美紗季、岡本成史
    • Organizer
      第92回日本細菌学会総会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 細菌のアミノ酸取り込みを利用した細菌増殖活性検出方法作出の可能性の検討2019

    • Author(s)
      松榮美希、湯淺善恵、小林正和、水谷明日香、川井恵一、岡本成史
    • Organizer
      第92回日本細菌学会総会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 高齢入院患者における誤嚥性肺炎発症に関連する口腔因子ならびに認知症の有無・種別と年齢による同因子の変化2019

    • Author(s)
      長谷剛志、小山岳海、大矢明日香、本保敦志、川尻秀一、岡本成史
    • Organizer
      第73回日本口腔科学会学術集会
    • Related Report
      2019 Annual Research Report
  • [Presentation] ラウリン酸の抗菌効果の新規測定法の開発および同方法による腸内細菌に対するラウリン酸の抗菌効果の検討2019

    • Author(s)
      松榮美希,森裕美子,長瀬賢史,杉山友太,平野里佳,栗原新,岡本成史
    • Organizer
      第12回北陸合同バイオシンポジウム
    • Related Report
      2019 Annual Research Report
  • [Presentation] Comparison of skin microbiome and skin physiological function between bedridden elderly with high risk of pressure injury and healthy people with low risk of pressurre injury2019

    • Author(s)
      Okamoto S, Nagase S, Ogaai K, Urai T, Shibata K, Matsubara E, Mutai K, Matsue M, Mori Y, Aoki M, Arisandi D, Sugama J
    • Organizer
      ASM Microbe 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Tape strips technique for collecting skin microbiome samples-comparison with swab methods.2019

    • Author(s)
      Okamoto S
    • Organizer
      Skin Microbiome Congress (Boston)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Comparison of skin microbiome between elderly with high risk of skin injury and healthy people with low risk of skin injury.2019

    • Author(s)
      Okamoto S
    • Organizer
      Asian Skin Microbiome 2.0 Congress
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Techniques for Collecting Skin Microbiome Samples: Limits and Perspective2019

    • Author(s)
      Shigefumi Okamoto
    • Organizer
      10th International Conference on Skin Aging and Challenges
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 皮膚細菌の採取法としてのテープストリップ法における粘着剤と細菌採取効率との関連-培養法と次世代シーケンスによる解析-2018

    • Author(s)
      柴田佳奈, 須釜淳子, 岡本成史, 大貝和裕
    • Organizer
      第6回看護理工学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 保存的治療で創閉鎖した褥瘡瘢痕部の変化と再発2018

    • Author(s)
      須釜淳子, 大貝和裕, 浦井珠恵, 岡本成史, 真田弘美
    • Organizer
      第 48 回日本創傷治癒学会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 歯の着色に対する認識はデンタルIQの指標になるか2018

    • Author(s)
      三浦由佳、江尻重文、平田佳永、岡本成史、須釜淳子
    • Organizer
      第29回甲信越北陸口腔保健研究会総会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 高齢者の年齢層別オーラルフレイル因子と誤嚥性肺炎との関連2018

    • Author(s)
      長谷剛志 , 小山岳海, 大矢明日香, 本保敦志, 長瀬賢史, 岡本成史
    • Organizer
      第58回全国国保地域医療学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 細菌増殖活性を検知する画像診断薬としての天然アミノ酸の可能性2018

    • Author(s)
      湯淺善恵、松榮美希、小林正和、森裕美子、水谷明日香、川井恵一、岡本成史
    • Organizer
      第71回日本細菌学会関西支部総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 口腔状態の変化に伴う腸内および口腔常在菌叢の変化の可能性2018

    • Author(s)
      小谷勇介、中村美紗季、長瀬賢史、松岡礼華、岡本成史
    • Organizer
      第71回日本細菌学会関西支部総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 寝たきり高齢者と健常高齢者,若年者間の皮膚細菌叢の比較検討2018

    • Author(s)
      長瀬賢史,大貝和裕,森裕美子,柴田佳奈,松原恵美,向井加奈恵,浦井珠恵,松榮美希,須釜淳子,岡本成史
    • Organizer
      第91回日本細菌学会総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 寝たきり高齢者と若年健常者,高齢健常者における皮膚細菌叢の相違に関する検討2018

    • Author(s)
      長瀬賢史,大貝和裕,浦井珠恵,向井加奈恵,須釜淳子,岡本成史
    • Organizer
      第33回日本環境感染学会総会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 療養型施設入居者を対象とした,褥瘡発症と皮膚細菌の関連についての臨床研究2017

    • Author(s)
      大貝和裕,松原瑛美,柴田佳奈,浦井珠恵,長瀬賢史,森裕美子,アンサンディ ディファ,向井加奈恵,岡本成史,須釜淳子
    • Organizer
      第47回日本創傷治癒学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 高齢者-若年者間における皮膚細菌叢を構成する細菌群の比較2017

    • Author(s)
      長瀬賢史,大貝和裕,向井加奈恵,浦井珠恵,須釜淳子,岡本成史
    • Organizer
      第5回看護理工学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 脂肪酸の腸内細菌叢構成細菌に対する抗菌効果の網羅的検討2017

    • Author(s)
      湯淺善恵,森裕美子,松榮美希,長瀬賢史,小谷勇介,栗原新,岡本成史
    • Organizer
      第10回北陸合同バイオシンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] Comparison of techniques for colletion of skin microbiome samples: swabbing method versus tape-stripping method2017

    • Author(s)
      Mori Y, Nagase S, Ogai K, Mastue M, Mukai K, Sugama J, Okamoto S
    • Organizer
      The 5th Congress of the Asia Association of Medical Laboratory Scientists.
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A novel and simple measuring method for antimicrobial activity of medium-chain fatty acids by using an optical density meter.2017

    • Author(s)
      Matsue M, Mori Y, Nagase S, Yuasa Y, Kotani Y, Hayashi K, Sugitani K, Okamoto S.
    • Organizer
      The 5th Congress of the Asia Association of Medical Laboratory Scientists
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Book] ヒト常在菌叢と生理機能・全身疾患 褥瘡後感染症・日和見感染症2020

    • Author(s)
      落合邦康 分担執筆 岡本成史
    • Total Pages
      325
    • Publisher
      シーエムシー出版
    • ISBN
      9784781315195
    • Related Report
      2020 Annual Research Report
  • [Book] ワクチン2018

    • Author(s)
      中山哲夫 他
    • Total Pages
      376
    • Publisher
      朝倉書店
    • ISBN
      9784254301151
    • Related Report
      2018 Annual Research Report
  • [Remarks] 金沢大学医薬保健研究域保健学系医療科学領域病態検査学講座病原微生物学[岡本成史研究室] 研究紹介

    • URL

      http://sokamoto-lab.w3.kanazawa-u.ac.jp/research/index.html

    • Related Report
      2017 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2022-01-27  

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