Nanowire/pore device for selective particle separation, stepwise particle desorption, and single particle detection
| Project/Area Number |
17H04803
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanobioscience
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| Research Institution | Nagoya University |
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Principal Investigator |
Yasui Takao 名古屋大学, 工学研究科, 准教授 (00630584)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
Fiscal Year 2019: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
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| Keywords | ナノワイヤ / マイクロ/ナノポア / ナノ材料 / ナノ空間 / 1分子計測 / ポアデバイス / ナノ界面 / 1分子科学 / ナノバイオ / マイクロヒーター / ヒーターデバイス |
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| Outline of Final Research Achievements |
Since a number of extracellular micro/nanoparticles with various size distribution are hazardous to our health, a way to identify these hazardous particles is strongly desired. However, conventional methodologies could not satisfy the requirement to identify the hazardous micro/nanoparticles, and we still feel vaguely insecure about the particles. In this research, we proposed a methodology to demonstrate selective separation, stepwise desorption, and single molecule detection using a nanowire/pore device. And then, we had a goal to achieve detection of the hazardous particles from "real" samples with various contaminants. Finally, the proposed methodology allows us to detect extracellular particles in our surroundings.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究の学術的な特色・独創的な点は、本手法でしか成し得ない物質の選択的分離・段階的脱離・1分子検出法を、ナノワイヤ/ポアデバイスを集積化した1つのデバイスにより創出するとともに、多種多様な夾雑物が混在するサンプルから極微量有害・危険物質(PM2.5/細菌/ウイルス等)の同時検知を実現するシステムを開発するところにある。また、本研究成果の社会的意義は、身の回りに存在する多種多様な極微量有害・危険物質に対する漠然とした不安を取り除き、これまでの有害・危険物質に対する認識を根底から覆すといった波及効果である。
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Report
(4 results)
Research Products
(57 results)
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[Journal Article] Rational Method of Monitoring Molecular Transformations on Metal-Oxide Nanowire Surfaces2019
Author(s)
C. Wang, T. Hosomi, K. Nagashima, T. Takahashi, G. Zhang, M. Kanai, H. Zeng, W. Mizukami, N. Shioya, T. Shimoaka, Y. Aoki, J. Terao, T. Hasegawa and T. Yanagida
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Journal Title
Nano Lett.
Volume: 19
Issue: 4
Pages: 2443-2449
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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