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Relationship between cerebral blood flow and cognitive decline in the elderly with heat stress

Research Project

Project/Area Number 17K01656
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Developmental mechanisms and the body works
Research InstitutionOsaka Electro-Communication University

Principal Investigator

OTA Akemi  大阪電気通信大学, 医療健康科学部, 教授 (70360732)

Co-Investigator(Kenkyū-buntansha) 岡崎 和伸  大阪公立大学, 都市健康・スポーツ研究センター, 教授 (70447754)
Project Period (FY) 2017-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords暑熱ストレス / 加齢 / 認知機能 / 脳血流 / 事象関連電位 / 脳血流速度 / 暑熱 / 暑熱負荷 / 姿勢ストレス
Outline of Final Research Achievements

Heat environment and postural change from supine to sitting position decrease cerebral blood flow. Since the circulatory response is attenuated in the elderly, the combination of heat and postural stress is likely to result in a significant decrease in resting cerebral blood flow, even when each is a mild load. The decrease in resting cerebral blood flow suppresses the increase in cerebral blood flow during cognitive activity. In this study, we examined the effects of aging on cognitive function and cerebral blood flow under heat stress. The results suggested that cognitive processing functions may decrease with aging, although no effect of aging on the reaction time to sound stimuli.

Academic Significance and Societal Importance of the Research Achievements

高齢者は若年者と比較して熱中症を発症しやすく、暑熱環境下においては、めまいや失神の発生が高くなる。暑熱環境下でも認知機能を維持し、正しい判断や行動を可能にすることは重要である。また、今後ますます高齢者が増加し、暑熱環境下で働く高齢労働者も増えると予測される。本研究では、暑熱環境下で音に対する反応時間が増悪していなくても、高齢者では認知処理機能が減弱している可能性があることを示唆した。これらの結果は、暑熱環境下で高齢者に生じる事故防止に役立つ基礎データとなる。

Report

(7 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (9 results)

All 2019 2018 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (8 results) (of which Int'l Joint Research: 5 results)

  • [Journal Article] The effects of aging on the distribution of cerebral blood flow with postural changes and mild hyperthermia2019

    • Author(s)
      Ota Akemi、Takeda Ryosuke、Imai Daiki、Naghavi Nooshin、Kawai Eriko、Saho Kosuke、Morita Emiko、Suzuki Yuta、Yokoyama Hisayo、Miyagawa Toshiaki、Okazaki Kazunobu
    • Journal Title

      European Journal of Applied Physiology

      Volume: 119 Issue: 5 Pages: 1261-1272

    • DOI

      10.1007/s00421-019-04118-5

    • NAID

      120006849936

    • URL

      https://ocu-omu.repo.nii.ac.jp/records/2019882

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] Takeda R,Imai D,Kawai E,Ota A,Saho K,Morita E,Suzuki Y,Yokoyama H,Takahashi H,Hayashi H,Kimura T,Okazaki K2019

    • Author(s)
      Heat acclimation program for firefighters reduced heat stress and improved thermal sensation and thermal comfort during exercise wearing with a firefighting suit.
    • Organizer
      Experimental Biology 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] The effect of aging on event-related potentials during mild-hyperthermia.2019

    • Author(s)
      Ota Akemi, Takeda Ryosuke, Imai Daiki, Kawai Eriko, Saho Kosuke, Morita Emiko, Suzuki Yuta, Yokoyama Hisayo, Okazaki Kazunobu
    • Organizer
      The Journal of Physiological Sciences
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] The Effect of Mild Heat Stress on Event-Related Potential in the Elderly2019

    • Author(s)
      Akemi Ota, Ryosuke Takeda, Daiki Imai, Eriko Kawai, Kosuke Saho, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, and Kazunobu Okazaki
    • Organizer
      Experimental Biology 2019
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 受動加温による軽度高体温が認知課題中の脳血流応答に及ぼす影響2018

    • Author(s)
      太田暁美、 竹田良祐、 今井大喜、 河合英理子、 佐保光祐、森田恵美子、鈴木雄太、 横山久代、 岡﨑和伸
    • Organizer
      第73回日本体力医学会大会
    • Related Report
      2018 Research-status Report
  • [Presentation] The effect of aging on event-related potentials during mild-hyperthermia2018

    • Author(s)
      Akemi Ota, Ryosuke Takeda, Daiki Imai, Eriko Kawai, Kosuke Saho, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, and Kazunobu Okazaki
    • Organizer
      9th Federation of the Asian and Oceanian Physiological Societies Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] A 3-month walking training does not improve thermal sensation in healthy elderly men2018

    • Author(s)
      Ryosuke Takeda, Daiki Imai, Akemi Ota, Nooshin Naghavi, Eriko Kawai, Genta Hanno, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, Kazunobu Okazaki
    • Organizer
      第95回日本生理学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 定期的運動の実施が高齢者の温度感覚に及ぼす影響2017

    • Author(s)
      竹田良祐,今井大喜,太田暁美,河合英理子,半野源太,Nagavi Nooshin,森田恵美子,鈴木雄太,横山久代,岡崎和伸
    • Organizer
      第72回日本体力医学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Ryosuke Takeda, Daiki Imai, Akemi Ota, Eriko Kawai, Genta Hanno, Nooshin Naghavi, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, Kazunobu Okazaki2017

    • Author(s)
      Whole body and skin thermal sensation are not improved with regular exercise in elderly men
    • Organizer
      The 17th International Conference On Environmental Ergonomics
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2024-01-30  

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