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Development and effectiveness testing of a prognosis improvement package program for obsessive-compulsive disorder

Research Project

Project/Area Number 17K04482
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Clinical psychology
Research InstitutionKeio University (2020-2022)
National Center of Neurology and Psychiatry (2017-2019)

Principal Investigator

KOBAYASHI YUKI  慶應義塾大学, 医学部(信濃町), 特任助教 (10741407)

Co-Investigator(Kenkyū-buntansha) 竹林 由武  福島県立医科大学, 医学部, 講師 (00747537)
堀越 勝  国立研究開発法人国立精神・神経医療研究センター, 認知行動療法センター, 特命部長 (60344850)
Project Period (FY) 2017-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords強迫症 / 予後 / 認知行動療法 / 予後改善
Outline of Final Research Achievements

In this study, we conducted a survey on the long-term prognosis of obsessive-compulsive disorder among patients who had completed non-pharmacological treatment for obsessive-compulsive disorder. Based on the results of the analysis, we examined four candidate interventions for each residual symptom: behavioral activation, psychological well-being, mindfulness, and response to family involvement. Additionally, refereeing to our past clinical experience, we discussed what order and how many orders we conduct the candidate interventions, and examined the feasibility of implementing the program in clinical settings. Based on the analysis results, we presented at conferences and papers on the relationship between obsessive-compulsive symptoms and mindfulness in obsessive-compulsive disorder, the relationship between autistic tendencies and well-being in obsessive-compulsive disorder, and the dissemination of cognitive-behavioral therapy and its barriers.

Academic Significance and Societal Importance of the Research Achievements

強迫症患者に対する予後調査、及び予後改善を目的としたプログラムは国内ではほぼ皆無である。本研究では、強迫症の長期予後に関する実際調査結果から、残遺症状別の介入候補として、行動活性化、ウェルビーイング、マインドフルネス、家族への巻き込みへの対応等を検討してプログラム構成について議論を重ねた。その効果検証は研究期間内に実施できなかったが、本プログラムは強迫症の予後改善のみならず、強迫症患者の家族機能を高めることも期待される。さらに、強迫症とマインドフルネスとの関連や、強迫症における自閉症傾向やウェルビーイングとの関連についても検討されたことから、本研究は臨床的にも社会的にも意義があると考える。

Report

(7 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (4 results)

All 2022 2021 2020

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (2 results)

  • [Journal Article] Associations of Autism Traits With Obsessive Compulsive Symptoms and Well-Being in Patients With Obsessive Compulsive Disorder: A Cross-Sectional Study2021

    • Author(s)
      Satomi Doi , Yuki Kobayashi , Yoshitake Takebayashi , Eriko Mizokawa , Atsuo Nakagawa , Masaru Mimura , Masaru Horikoshi
    • Journal Title

      Frontiers in Psychology

      Volume: 12 Pages: 697717-697717

    • DOI

      10.3389/fpsyg.2021.697717

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pseudo-continuous arterial spin labeling MRI study of patients with obsessive?compulsive disorder2020

    • Author(s)
      Ota Miho、Kanie Ayako、Kobayashi Yuki、Nakajima Aiichiro、Sato Noriko、Horikoshi Masaru
    • Journal Title

      Psychiatry Research: Neuroimaging

      Volume: 303 Pages: 111124-111124

    • DOI

      10.1016/j.pscychresns.2020.111124

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Presentation] 認知行動療法における現状とその課題~厚生労働省認知行動療法研修事業アンケート結果より~2022

    • Author(s)
      小林由季, 中川敦夫, 田島美幸, 満田大, 大野裕, 三村將
    • Organizer
      第22回日本認知療法・認知行動療法学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 強迫症患者における強迫症状とマインドフルネスとの関連2020

    • Author(s)
      小林由季 中川敦夫 竹林由武 土井理美 溝川英里子 堀越勝
    • Organizer
      第20回認知療法・認知行動療法学会
    • Related Report
      2020 Research-status Report

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Published: 2017-04-28   Modified: 2024-01-30  

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