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Study on measurement method for estimation of brain activated region by near infrared spectroscopy

Research Project

Project/Area Number 17K06477
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionTokyo Metropolitan College of Industrial Technology

Principal Investigator

Fukuda Keiko  東京都立産業技術高等専門学校, ものづくり工学科, 教授 (70396266)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords近赤外分光法 / 脳機能計測 / 脳血流 / 皮膚血流 / 計測工学 / 生体工学
Outline of Final Research Achievements

We research on the characteristics of NIRS signal with brain activity and estimation of its activated area. For analyzing the brain activity in frontal region quantitatively, we proposed stoop GO/NO-GO task and confirmed the response with the task by fMRI measurement. Then, we applied the task to NIRS measurement. The activated region of NIRS measurement showed the same tendency with that of fMRI measurement, we assume that the task is applicable for NIRS measurement. Further, we improved the cancellation method of superficial blood flow by the expansion of measurement area and applied the analytical method to confirmed the cancellation effect.

Academic Significance and Societal Importance of the Research Achievements

小型で低拘束の近赤外分光法により脳活動の強度と領域が推定できること、特に前頭部の脳反応を定量的に評価することは、思考や記憶などの認知判断を評価する上で重要である。発達段階において学習に重要な役割を果たすワーキングメモリーの活用状況の把握や高齢者の認知能力の評価や脳トレーニング効果の検証に役立つ。血流動態変化の補正機能に脳反応信号の発生領域をより正確に推定できることはNIRS計測の信憑性を高める上で重要である。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (20 results)

All 2020 2019 2018 2017

All Journal Article (5 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results) Presentation (14 results) (of which Int'l Joint Research: 4 results) Book (1 results)

  • [Journal Article] 短期記憶課題に伴うNIRS 信号の時間特性の解析2020

    • Author(s)
      馬場健太,福田恵子
    • Journal Title

      電子情報通信学会信学技報

      Volume: IEICE-119 Pages: 65-68

    • Related Report
      2019 Annual Research Report
  • [Journal Article] 行動抑制課題に対する脳反応部位 の NIRSによる解析2020

    • Author(s)
      杉山侑,福田恵子
    • Journal Title

      電子情報通信学会信学技報

      Volume: IEICE-119 Pages: 73-76

    • Related Report
      2019 Annual Research Report
  • [Journal Article] Cancellation of Superficial Blood Flow in Brain Function Measurements Using Near-Infrared Spectroscopy2019

    • Author(s)
      Fukuda Keiko、Motoyoshi Daisuke、Sato Daisuke
    • Journal Title

      2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

      Volume: 1 Pages: 486-489

    • DOI

      10.1109/embc.2019.8857057

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Suppression of superficial hemodynamic changes using a depth-selective filter in near-infrared spectroscopy measurements2018

    • Author(s)
      Iwata Yuki、Fukuda Keiko、Fujii Mamiko
    • Journal Title

      Proceeding of Biomedical Engineering International Conference

      Volume: 1 Pages: 1-8

    • DOI

      10.1109/bmeicon.2018.8609927

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Cancellation Method of Signal Fluctuations in Brain Function Measurements Using Near-Infrared Spectroscopy2018

    • Author(s)
      Fukuda Keiko、Sato Daisuke
    • Journal Title

      Proceedings ofInternational Conference of the IEEE Engineering in Medicine and Biology Society

      Volume: 1 Pages: 3302-3305

    • DOI

      10.1109/embc.2018.8512900

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Experimental tasks using fMRI measurement for evaluating NIRS signal characteristics2019

    • Author(s)
      [1]Keiko Fukuda, Shun Seki, Ren Kunii, Li-qun Wang, Keita Tanaka and Shinya Kuriki
    • Organizer
      IEEE Engineering in Medicine and Biology Society Conference
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 短期記憶課題を用いたNIRS による脳活動の評価法の検討2019

    • Author(s)
      福田 恵子, 三田 哲大
    • Organizer
      第58回日本生体医工学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 深さ選択性フィルタによる皮膚血流変化の低減2019

    • Author(s)
      福田 恵子, 岩田 勇樹, 藤井 麻美子
    • Organizer
      第58回日本生体医工学会大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] NIRS実験を目的としたfMRIによる実験課題の作成と評価2019

    • Author(s)
      関駿、國井怜、福田恵子、王力群
    • Organizer
      第21回日本ヒト脳機能マッピング学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 近赤外分光法における皮膚血流の影響の低減2019

    • Author(s)
      岩田勇樹、福田恵子、藤井麻美子
    • Organizer
      ライフサポート学会 フロンティア講演会
    • Related Report
      2018 Research-status Report
  • [Presentation] Using a depth-selective filter to suppress superficial hemodynamic changes2018

    • Author(s)
      Iwata Yuki、Fukuda Keiko、Fujii Mamiko
    • Organizer
      fNIRS conference
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 近赤外分光法による脳機能計測における外乱の検出と補正法の検討2018

    • Author(s)
      福田恵子、佐藤大輔
    • Organizer
      第57回生体医工学会大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 深さ選択性拡散光イメージングの三角形センサ配置への適用2018

    • Author(s)
      岩田勇樹、福田恵子、藤井麻美子
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] NIRS計測における血液量変動の検出と補正手段の検討2018

    • Author(s)
      佐藤大輔、福田恵子
    • Organizer
      電子情報通信学会総合大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 近赤外分光法による筋交感神経活動の計測に向けた受光回路の特性評価2018

    • Author(s)
      岩田勇樹、福田恵子
    • Organizer
      電気学会電子回路研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] Cancellation Method of Signal Fluctuations in Brain Function Measurements Using Near-Infrared Spectroscopy2018

    • Author(s)
      Keiko Fukuda, Daisuke Sato
    • Organizer
      40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Measurement and evaluation of brain hemodynamic change according dietary intake by near-infrared spectroscopy2017

    • Author(s)
      Keiko Fukuda, Yuuki Muramatsu, and Masahiro Hasegawa
    • Organizer
      9th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 近赤外分光法による筋交感神経活動の計測に向けた基礎検討2017

    • Author(s)
      岩田勇樹、福田恵子
    • Organizer
      2017年電子情報通信学会基礎・境界ソサイエティ/NORLTAソサエティ大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 近赤外分光法による筋交感神経活動の評価への試み2017

    • Author(s)
      福田恵子、岩田勇樹
    • Organizer
      日本臨床生理学会総会
    • Related Report
      2017 Research-status Report
  • [Book] 電気・電子計測工学 (改訂版)- 新SI対応 -2020

    • Author(s)
      吉澤 昌純、降矢典雄、福田恵子、吉村拓巳、高崎和之、西山明彦
    • Total Pages
      222
    • Publisher
      コロナ社
    • ISBN
      9784339012156
    • Related Report
      2019 Annual Research Report

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Published: 2017-04-28   Modified: 2021-02-19  

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