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Identification and functional analysis of functional peptides involved in the cold stress response

Research Project

Project/Area Number 17K07690
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plant protection science
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

Nakaminami Kentaro  国立研究開発法人理化学研究所, 環境資源科学研究センター, 研究員 (40513403)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords低温ストレス / シロイヌナズナ / 機能性ペプチド / 環境ストレス応答・耐性 / 低温ストレス応答・耐性
Outline of Final Research Achievements

In order to understand the response and adaptation mechanisms of plants to low temperature stress, which is one of the major environmental stresses, is an important study that will lead to the expansion of the growing area and increase in growth and yield of crops. The aim of this study was to identify novel functional peptides involved in cold stress tolerance and the resumption of growth after overwintering. In addition, to analyze the function of the identified peptides, treatment test of artificial synthesis peptides to plants and evaluates cold stress tolerance.
Since natural peptides are relatively safer than chemical fertilizers, the discovery of novel functional peptides in this study is expected to contribute to the development of new farming methods to enhance cold stress tolerance in crops.

Academic Significance and Societal Importance of the Research Achievements

ペプチドはアミノ酸がいくつか結合している天然物であり,様々な機能を有することから現在では,医療や食品などにも利用されている.化学合成された薬品と比較して安全性が高いため,製品などに応用されやすい.本研究は,植物の低温ストレス耐性を強化する機能性ペプチドの発見と機能解析を目的としており,新たなペプチドの発見により,冷害などで生育不良を起こす作物の改善や,冬季間の加温されたハウス栽培での作物の生育促進など,ペプチドを利用した新規農法の開発が期待される.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (7 results)

All 2020 2019 2018

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] Biological function of changes in RNA metabolism in plant adaptation to abiotic stress2019

    • Author(s)
      Matsui, A., Nakaminami, K. and Seki, M.
    • Journal Title

      Plant Cell Physiol.

      Volume: 60 Issue: 9 Pages: 1897-1905

    • DOI

      10.1093/pcp/pcz068

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants2018

    • Author(s)
      Nakaminami Kentaro、Okamoto Masanori、Higuchi-Takeuchi Mieko、Yoshizumi Takeshi、Yamaguchi Yube、Fukao Yoichiro、Shimizu Minami、Ohashi Chihiro、Tanaka Maho、Matsui Minami、Shinozaki Kazuo、Seki Motoaki、Hanada Kousuke
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 115 Issue: 22 Pages: 5810-5815

    • DOI

      10.1073/pnas.1719491115

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] RNA Regulation in Plant Cold Stress Response2018

    • Author(s)
      Nakaminami Kentaro、Seki Motoaki
    • Journal Title

      Adv Exp Med Biol

      Volume: 1081 Pages: 23-44

    • DOI

      10.1007/978-981-13-1244-1_2

    • ISBN
      9789811312434, 9789811312441
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants2018

    • Author(s)
      Kentaro Nakaminami, Masanori Okamoto, Mieko Higuchi-Takeuchi, Takeshi Yoshizumi, Yube Yamaguchi, Yoichiro Fukao, Minami Shimizu, Chihiro Ohashi, Maho Tanaka, Minami Matsui, Kazuo Shinozaki, Motoaki Seki, and Kousuke Hanada
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 印刷中

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Oligouridylate binding protein 1b (UBP1b) involved in heat stress adaptation though mRNA protection2020

    • Author(s)
      Kentaro Nakaminami, Cam Chau Nguyen Thi, Akihiro Matsui, Motoaki Seki
    • Organizer
      第61回日本植物生理学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Functional small peptide related to cold respons2018

    • Author(s)
      Kentaro Nakaminami, Motoaki Seki
    • Organizer
      11th International Plant Cold Hardiness Seminar
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Expression profile of small coding genes during cold acclimation and de-acclimation in plants2018

    • Author(s)
      中南 健太郎,田中 真帆,高橋 聡史,松井 章浩,武田 智之, 金 有王, 花田 耕介,関 原明
    • Organizer
      第59回日本植物生理学会年会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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