Synthesis of Z-type ligand-containing metal complex with electron-withdrawing group and its catalytic reaction
| Project/Area Number |
17K08209
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kobe Gakuin University (2019)
Kanazawa University (2017-2018) |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | Z型配位子 / 金触媒 / 環化反応 / 金 / 触媒反応 / 金属活性化 / 有機金属化学 |
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| Outline of Final Research Achievements |
The effect of electron-accepting Z-type ligands on the reaction of adjacent metals is still unexplored. In this study, a new Z-type ligand-containing metal complex having an electron-withdrawing group was synthesized for the purpose of creating new reactivity and applied to a catalytic reaction .In conclusion, successive 7-exo cyclization, carboxylation, intramolecular [4 + 2] type cycloaddition, and 7-endo-trig type cycloaddition proceeded.
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| Academic Significance and Societal Importance of the Research Achievements |
今回、未だ解明の進んでいないZ型配位子の機能性を調査した。その結果、配位子が隣接金属の電子を受容することによるLewis酸性の向上に伴う、有機触媒反応の反応性向上が見られることを明らかにした。また、その電子受容性に伴う金属の型式酸化数の変化に着目した新規反応性を創出するに至った。これら一連の結果は、これまであまり使用されてこなかったZ型配位子が従来にはない反応性を提供することを強く示唆したものであり、高い学術的意義を有していると確信している。
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Report
(4 results)
Research Products
(43 results)
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[Journal Article] Substrate Specific Silver(I)-Catalyzed Cycloisomerization of Diene Involving Alkyl Rearrangements: Syntheses of 1,2,5,6-Tetrahydrocuminic Acid, <i>p</i>-Menth-3-en-7-ol, and <i>p</i>-Menth-3-en-7-al2017
Author(s)
Inagaki, F.; Matsumoto, M.; Hira, S.; Mukai, C.
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Journal Title
Chemical and Pharmaceutical Bulletin
Volume: 65
Issue: 9
Pages: 822-825
DOI
NAID
ISSN
0009-2363, 1347-5223
Related Report
Peer Reviewed
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[Presentation] Synthesis of (Au→B)8-type gold complex and its catalytic reaction2019
Author(s)
Hiroto Tanishima, Ayaka Uchda, Ryoya Kamo, Kazuki Kawasaki, Hikari Kawamitsu, Chihiro Kiyohara, Daisuke Naito, Motoki Matsuo, Kakeru Maeda, Ryo Murakami, Fuyuhiko Inagaki
Organizer
第４回精密制御反応場国際シンポジウム
Related Report
Int'l Joint Research
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