| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Proteins are composed of 20 kinds of amino acids, which play an important role in all biological activities. Although homeostasis of the amino acid concentration in blood is maintained, it has recently been reported that the balance of D,L-amino acid concentrations in blood and urine is unbalanced when a particular disease is involved. Therefore, quantification of D,L-amino acids in blood of healthy persons and schizophrenia patients was performed using HPLC. Among the quantified amino acids, D,L-serine and D,L-alanine were further analyzed to investigate their association with clinical symptoms.
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