Molecular differences in the microsatellite stable phenotype between left-sided and right-sided colorectal cancer

• Project/Area Number: 17K08700
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Human pathology
• Research Institution: Iwate Medical University
• Principal Investigator: SUGAI TAMOTSU 岩手医科大学, 医学部, 教授 (20187628)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 大腸癌 / 左右差 / 発生部位 / コピー数異常 / TP53変異 / KRAS変異 / 右側大腸癌 / メチル化 / 右側癌 / 左側癌 / 遺伝子変異 / コピー数変化 / メチレーション / Microsatellite stable / Copy Number alteration / TP53 / KRAS / BRAF / 腫瘍発生 / 左側 / 右側 / MSS / 分子異常

Outline of Final Research Achievements

To identify genomic differences between MSS type left-sided CRC (LC) and right-sided CRC (RC), we examined a comprehensive molecular analysis using crypt isolation with samples from 92 sporadic CRCs. Microsatellite instability and DNA methylation status were determined. Additionally, mutations in the TP53, KRAS, BRAF, and PIK3CA genes were examined. Finally, a genome-wide study using a single nucleotide polymorphism array was performed. We examined 71 CRCs with the MSS phenotype (LC 56; RC, 15) in the 92 CRCs. Mutations in KRAS were associated with RC with the MSS phenotype, whereas mutations in TP53 were more frequently found in LC with the MSS phenotype. There were significant differences in the frequencies of KRAS and TP53 mutations between LC and RC with the MSS phenotype. CNA gains were associated with LC with the MSS phenotype. These findings suggested that the molecular pathogenesis of the MSS phenotype in LC was different from that in RC.

Academic Significance and Societal Importance of the Research Achievements

大腸癌の発生機序が発生部位によって異なっているという指摘はこれまでなされていたが、それは右側にMSIを引き起こす癌が多いことを指摘している報告が多かった。大腸癌の分子病型では右側発生であってもMSS型が多く、MSS型癌の発生部位に基づいた分子レベルの違いを明らかにした報告は皆無である。本研究では発生部位に基づいたMSS型癌の特徴が明らかになった。近年右側発生の大腸癌の頻度が上昇する傾向があり、発生部位に基づいた大腸癌の分子機序を明らかにすることは大腸癌診療においても欠かすことのできない知見を提供するものと思われる。

Research Products

• [Journal Article] Multi-institutional re-evaluation of prognostic factors in chromophobe renal cell carcinoma: proposal of a novel two-tiered grading (2020)
  • Author(s): Ohashi, R. Martignoni, G. Hartmann, A. Calio, A. Segala, D. Stohr, C. Wach, S. Erlmeier, F. Weichert, W. Autenrieth, M. Schraml, P. Rupp, N. J. Ohe, C. Otsuki, Y. Kawasaki, T. Kobayashi, H. Kobayashi, K. Miyazaki, T. Shibuya, H. Tsuzuki, T. Nagashima, Y. Ajioka, Y. Moch, H. et al.
  • Journal Title: Virchows Arch Volume: 476 Issue: 3 Pages: 409-418
  • DOI: 10.1007/s00428-019-02710-w
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Microvascular density under magnifying narrow-band imaging endoscopy in colorectal epithelial neoplasms. (2020)
  • Author(s): Gonai T, Kawasaki K, Nakamura S, Yanai S, Akasaka R, Sato K, Toya Y, Asakura K, Urushikubo J, Fujita Y, Eizuka M, Uesugi N, Sugai T, Matsumoto T.
  • Journal Title: Intest Res Volume: 18 Issue: 1 Pages: 107-114
  • DOI: 10.5217/ir.2019.00061
  • Peer Reviewed / Open Access
• [Journal Article] Differential expression of microRNAs in colorectal cancer: Different patterns between isolated cancer gland and stromal cells. (2020)
  • Author(s): Sato A, Fujita Y, Otsuka K, Sasaki A, Suzuki H, Matsumoto T, Sugai T.
  • Journal Title: Pathol Int Volume: 70 Issue: 1 Pages: 21-30
  • DOI: 10.1111/pin.12872
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive analysis of somatic copy number alterations in clear cell renal cell carcinoma. (2020)
  • Author(s): Tsuyukubo T, Ishida K, Osakabe M, Shiomi E, Kato R, Takata R, Obara W, Sugai T.
  • Journal Title: Mol Carcinog Volume: 59 Issue: 4 Pages: 412-424
  • DOI: 10.1002/mc.23164
  • Peer Reviewed / Open Access
• [Journal Article] Significance of gene mutations in the Wnt signaling pathway in traditional serrated adenomas of the colon and rectum (2020)
  • Author(s): Nakanishi, H. Sawada, T. Kaizaki, Y. Ota, R. Suzuki, H. Yamamoto, E. Aoki, H. Eizuka, M. Hasatani, K. Takahashi, N. Inagaki, S. Ebi, M. Kato, H. Kubota, E. Kataoka, H. Takahashi, S. Tokino, T. Minamoto, T. Sugai, T. Sasaki, Y.
  • Journal Title: PLoS One Volume: 15 Issue: 2 Pages: e0229262-e0229262
  • DOI: 10.1371/journal.pone.0229262
  • Peer Reviewed / Open Access
• [Journal Article] A diagnostic algorithm of magnifying endoscopy with crystal violet staining for non-ampullary duodenal epithelial tumors. (2020)
  • Author(s): Toya Y, Endo M, Oizumi T, Akasaka R, Yanai S, Kawasaki K, Nakamura S, Eizuka M, Fujita Y, Uesugi N, Ishida K, Sugai T, Matsumoto T.
  • Journal Title: Dig Endosc Volume: - Issue: 7 Pages: 1066-1073
  • DOI: 10.1111/den.13640
  • Peer Reviewed / Open Access
• [Journal Article] White Opaque Substance Under Narrow-Band Imaging Colonoscopy May Hinder Microvascular Pattern Recognition in Colorectal Tumors. (2020)
  • Author(s): Kawasaki K, Sugai T, Matsumoto T.
  • Journal Title: Dig Endosc Volume: - Issue: 5 Pages: 826-826
  • DOI: 10.1111/den.13667
  • Peer Reviewed / Open Access
• [Journal Article] Effects of Laparoscopic Sleeve Gastrectomy on Non-Alcoholic Steatohepatitis and Liver Fibrosis in Japanese Patients with Severe Obesity. (2020)
  • Author(s): Nikai H, Ishida K, Umemura A, Baba S, Nitta H, Sugai T, Sasaki A.
  • Journal Title: Obes Surg Volume: - Issue: 7 Pages: 2579-2587
  • DOI: 10.1007/s11695-020-04515-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Upregulation of AEBP1 in endothelial cells promotes tumor angiogenesis in colorectal cancer (2020)
  • Author(s): Yorozu Akira、Yamamoto Eiichiro、Niinuma Takeshi、Tsuyada Akihiro、Maruyama Reo、Kitajima Hiroshi、Numata Yuto、Kai Masahiro、Sudo Gota、Kubo Toshiyuki、Nishidate Toshihiko、Okita Kenji、Takemasa Ichiro、Nakase Hiroshi、Sugai Tamotsu、Takano Kenichi、Suzuki Hiromu
  • Journal Title: Cancer Science Volume: － Issue: 5 Pages: 1631-1644
  • DOI: 10.1111/cas.14360
  • Peer Reviewed / Open Access
• [Journal Article] Clinical usefulness of magnifying colonoscopy for the diagnosis of ulcerative colitis-associated neoplasia. (2019)
  • Author(s): Kawasaki K, Nakamura S, Esaki M, Kurahara K, Eizuka M, Nuki Y, Kochi S, Fujiwara M, Oshiro Y, Sugai T, Matsumoto T.
  • Journal Title: JACC Basic Transl Sci. Volume: 4 Issue: S1 Pages: 234-247
  • DOI: 10.1111/den.13382
  • Peer Reviewed / Open Access
• [Journal Article] UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells (2019)
  • Author(s): Niinuma Takeshi、Kitajima Hiroshi、Kai Masahiro、Yamamoto Eiichiro、Yorozu Akira、Ishiguro Kazuya、Sasaki Hajime、Sudo Gota、Toyota Mutsumi、Hatahira Tomo、Maruyama Reo、Tokino Takashi、Nakase Hiroshi、Sugai Tamotsu、Suzuki Hiromu
  • Journal Title: Clinical Epigenetics Volume: 11 Issue: 1 Pages: 70-70
  • DOI: 10.1186/s13148-019-0668-3
  • Peer Reviewed / Open Access
• [Journal Article] Gastric mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) with pancreatic acinar differentiation: a case report. (2019)
  • Author(s): Fujita Y, Uesugi N, Sugimoto R, Eizuka M, Matsumoto T, Sugai T.
  • Journal Title: Diagn Pathol. Volume: 14 Issue: 1 Pages: 38-38
  • DOI: 10.1186/s13000-019-0815-3
  • Peer Reviewed / Open Access
• [Journal Article] Methotrexate-Associated Lymphoproliferative Disorder of the Stomach Observed by Magnifying Narrow-Band Imaging Endoscopy. (2019)
  • Author(s): Kawasaki K, Eizuka M, Nakamura S, Sugai T, Matsumoto T.
  • Journal Title: J Gastrointestin Liver Dis. Volume: 28 Pages: 145-145
  • DOI: 10.15403/jgld-170
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of Expression Patterns of MicroRNAs That Are Closely Associated With Renal Carcinogenesis. (2019)
  • Author(s): Shiomi E, Sugai T, Ishida K, Osakabe M, Tsuyukubo T, Kato Y, Takata R, Obara W.
  • Journal Title: Front Oncol. Volume: 9 Pages: 431-431
  • DOI: 10.3389/fonc.2019.00431
  • Peer Reviewed / Open Access
• [Journal Article] Gastrointestinal: Discordant lymphoma consisting of ileal follicular lymphoma and colonic mucosa-associated lymphoid tissue lymphoma. (2019)
  • Author(s): Kawasaki K, Eizuka M, Nakamura S, Sugai T, Matsumoto T.
  • Journal Title: J Gastroenterol Hepatol. Volume: 34 Issue: 11 Pages: 1894-1894
  • DOI: 10.1111/jgh.14723
  • Peer Reviewed / Open Access
• [Journal Article] Ustekinumab Improves Paradoxical Enteropathy Associated With Psoriasis Arthritis. (2019)
  • Author(s): Urushikubo J, Kawasaki K, Eizuka M, Yanai S, Nakamura S, Sugai T, Matsumoto T.
  • Journal Title: Inflamm Bowel Dis. Volume: 25 Issue: 10 Pages: 128-129
  • DOI: 10.1093/ibd/izz154
  • Peer Reviewed
• [Journal Article] Melanocytic Nevus of the Colon. (2019)
  • Author(s): Uesugi N, Tateno H, Yokoyama H, Abe S, Sugimoto R, Sugai T.
  • Journal Title: Case Rep Gastroenterol. Volume: 13 Issue: 2 Pages: 271-274
  • DOI: 10.1159/000501196
  • Peer Reviewed / Open Access
• [Journal Article] Risk Factors for Post-gastric Endoscopic Submucosal Dissection Bleeding with a Special Emphasis on Anticoagulant Therapy. (2019)
  • Author(s): Toya Y, Endo M, Oizumi T, Akasaka R, Yanai S, Kawasaki K, Nakamura S, Eizuka M, Fujita Y, Uesugi N, Sugai T, Matsumoto T.
  • Journal Title: Dig Dis Sci. Volume: 65 Issue: 2 Pages: 557-564
  • DOI: 10.1007/s10620-019-05776-3
  • Peer Reviewed / Open Access
• [Journal Article] The expression of gastrointestinal differentiation markers in extrahepatic cholangiocarcinoma: clinicopathological significance based on tumor location. (2019)
  • Author(s): Ishida K, Osakabe M, Eizuka M, Tai S, Sugimoto R, Fujita Y, Katagiri H, Takahara T, Uesugi N, Nitta H, Sasaki A, Sugai T.
  • Journal Title: Hum Pathol. Volume: 92 Pages: 91-100
  • DOI: 10.1016/j.humpath.2019.08.002
  • Peer Reviewed / Open Access
• [Journal Article] Impacts on Histological Features and 11C-Methyl-L-methionine Uptake After “One-Shot” Administration with Bevacizumab Before Surgery in Newly Diagnosed Glioblastoma (2019)
  • Author(s): Beppu Takaaki、Sato Yuichi、Yamada Noriyuki、Terasaki Kazunori、Sasaki Toshiaki、Sugai Tamotsu、Ogasawara Kuniaki
  • Journal Title: Translational Oncology Volume: 12 Issue: 11 Pages: 1480-1487
  • DOI: 10.1016/j.tranon.2019.08.002
  • Peer Reviewed / Open Access
• [Journal Article] Immune checkpoint inhibitor-induced diarrhea: A clinicopathological study of eleven patients. (2019)
  • Author(s): Yanai S, Nakamura S, Kawasaki K, Toya Y, Akasaka R, Oizumi T, Ishida K, Sugai T, Matsumoto T.
  • Journal Title: Dig Endosc. Volume: - Issue: 4 Pages: 616-620
  • DOI: 10.1111/den.13555
  • Peer Reviewed / Open Access
• [Journal Article] Classic Chromophobe Renal Cell Carcinoma Incur a Larger Number of Chromosomal Losses Than Seen in the Eosinophilic Subtype (2019)
  • Author(s): Ohashi, R Schraml, P Angori, S Batavia, Aashil A Rupp, NJ Ohe, C Otsuki, Y Kawasaki, T Kobayashi, K Miyazaki, T Shibuya, H Nagashima, Y, Ajioka, Y, Moch, H et al.
  • Journal Title: Cancers (Basel) Volume: 11 Issue: 10 Pages: 1492-1505
  • DOI: 10.3390/cancers11101492
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Primary plasmacytoma in the cerebellum: A case report and literature review. (2019)
  • Author(s): Yanagihara W, Beppu T, Ogasawara Y, Ito S, Sato Y, Sugai T, Ogasawara K.
  • Journal Title: World Neurosurg. Volume: 134 Pages: 10-13
  • DOI: 10.1016/j.wneu.2019.10.036
  • Peer Reviewed / Open Access
• [Journal Article] Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after (2019)
  • Author(s): Sasaki T, Suzuki Y, Kakisaka K, Wang T, Ishida K, Suzuki A, Abe H, Sugai T, Takikawa Y
  • Journal Title: FEBS Open Bio Volume: 0 Issue: 12 Pages: 0-0
  • DOI: 10.1002/2211-5463.12750
  • Peer Reviewed / Open Access
• [Journal Article] Gastrointestinal involvement in patients with vasculitis: IgA vasculitis and eosinophilic granulomatosis with polyangiitis. (2019)
  • Author(s): Kawasaki K, Nakamura S, Esaki M, Kurahara K, Eizuka M, Okamoto Y, Hirata T, Hirahashi M, Oshiro Y, Yanai S, Sato K, Toya Y, Maemondo M, Terayama Y, Sugai T, Matsumoto T.
  • Journal Title: Endosc Int Open. Volume: 7 Issue: 11 Pages: 1333-1343
  • DOI: 10.1055/a-0977-2777
  • Peer Reviewed / Open Access
• [Journal Article] Sessile serrated adenoma/polyp showed rapid malignant transformation in the final 13?months (2019)
  • Author(s): Amemori Sadahiro、Yamano Hiro‐o、Tanaka Yoshihito、Yoshikawa Kenjiro、Matsushita Hiro‐o、Takagi Ryo、Harada Eiji、Yoshida Yuko、Tsuda Kazunori、Kato Bunichiro、Tamura Eri、Eizuka Makoto、Sugai Tamotsu、Adachi Yasushi、Yamamoto Eiichiro、Suzuki Hiromu、Nakase Hiroshi
  • Journal Title: Digestive Endoscopy Volume: － Issue: 6 Pages: 979-983
  • DOI: 10.1111/den.13572
  • Peer Reviewed / Open Access
• [Journal Article] Elemental and mutational analysis of lung tissue in lung adenocarcinoma patients. (2019)
  • Author(s): Chiba R, Morikawa N, Sera K, Ishida K, Nagashima H, Shigeeda W, Deguchi H, Tomoyasu M, Hosokawa T, Saito H, Sugai T, Yamauchi K, Maemondo M.
  • Journal Title: Transl Lung Cancer Res. Volume: 8 Issue: S3 Pages: 224-234
  • DOI: 10.21037/tlcr.2019.08.18
  • Peer Reviewed / Open Access
• [Journal Article] Sarcomatoid change associated with epithelial-mesenchymal transition in mucinous tubular and spindle cell carcinoma of the kidney: a case report. (2019)
  • Author(s): Sugimoto R, Uesugi N, Yamada N, Osakabe M, Fujita Y, Eizuka M, Kato R, Ishida K, Obara W, Nagashima Y, Sugai T.
  • Journal Title: Int J Clin Exp Pathol. Volume: 12 Pages: 2767-2771
  • Peer Reviewed
• [Journal Article] An extremely rare case who underwent total remnant pancreatectomy due to recurrent pancreatic metastasis of intraductal tubulopapillary neoplasm. (2019)
  • Author(s): Umemura A, Ishida K, Nitta H, Takahara T, Hasegawa Y, Makabe K, Sugai T, Sasaki A.
  • Journal Title: Clin J Gastroenterol. Volume: 12 Issue: 2 Pages: 153-159
  • DOI: 10.1007/s12328-018-0913-x
  • Peer Reviewed / Open Access
• [Journal Article] Expression of Epithelial-Mesenchymal Transition Proteins in Pancreatic Anaplastic (Undifferentiated) Carcinoma. (2019)
  • Author(s): Ishida K, Yamashita R, Osakabe M, Uesugi N, Yamada N, Nitta H, Fujishima F, Motoi F, Suzuki H, Shimamura H, Noda Y, Sawai T, Unno M, Sasano H, Sasaki A, Sugai T.
  • Journal Title: Pancreas. Volume: 48 Issue: 1 Pages: 36-42
  • DOI: 10.1097/mpa.0000000000001199
  • Peer Reviewed / Open Access
• [Journal Article] Distinction between Chronic Enteropathy Associated with the SLCO2A1 Gene and Crohn's Disease. (2019)
  • Author(s): Yanai S, Yamaguchi S, Nakamura S, Kawasaki K, Toya Y, Yamada N, Eizuka M, Uesugi N, Umeno J, Esaki M, Okimoto E, Ishihara S, Sugai T, Matsumoto T.
  • Journal Title: Gut Liver. Volume: 13 Issue: 1 Pages: 62-66
  • DOI: 10.5009/gnl18261
  • Peer Reviewed / Open Access
• [Journal Article] Integrated Analysis of the Endoscopic, Pathological and Molecular Characteristics of Colorectal Tumorigenesis. (2019)
  • Author(s): Suzuki H, Yamamoto E, Yamano HO, Nakase H, Sugai T.
  • Journal Title: Digestion. Volume: 99 Issue: 1 Pages: 33-38
  • DOI: 10.1159/000494410
  • Peer Reviewed / Open Access
• [Journal Article] Long-term outcomes and prognostic factors with non-curative endoscopic submucosal dissection for gastric cancer in elderly patients aged ≧75 years. (2019)
  • Author(s): Toya Y, Endo M, Nakamura S, Akasaka R, Yanai S, Kawasaki K, Koeda K, Eizuka M, Fujita Y, Uesugi N, Ishida K, Sugai T, Matsumoto T.
  • Journal Title: Gastric Cancer. Volume: 印刷中 Issue: 4 Pages: 877-878
  • DOI: 10.1007/s10120-018-00913-9
  • NAID: 40021926074
  • Peer Reviewed
• [Journal Article] Evaluation of Sentinel Lymph Node Biopsy for Eccrine Porocarcinoma. (2019)
  • Author(s): Tsunoda K, Onishi M, Maeda F, Akasaka T, Sugai T, Amano H.
  • Journal Title: Acta Derm Venereol. Volume: 印刷中 Issue: 7 Pages: 691-692
  • DOI: 10.2340/00015555-3173
  • Peer Reviewed / Open Access
• [Journal Article] Response to the letter by Sumida et al. regarding our manuscript "Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease". (2019)
  • Author(s): Kakisaka K, Suzuki Y, Fujiwara Y, Abe T, Yonezawa M, Kuroda H, Ishida K, Sugai T, Takikawa Y.
  • Journal Title: J Gastroenterol. Volume: 54 Issue: 5 Pages: 476-477
  • DOI: 10.1007/s00535-019-01574-w
  • Peer Reviewed
• [Journal Article] Immunohistochemical analysis of the epithelial to mesenchymal transition in uterine carcinosarcoma. (2019)
  • Author(s): Osakabe M, Fukagawa D, Sato C, Sugimoto R, Uesugi N, Ishida K, Itamochi H, Sugiyama T, Sugai T.
  • Journal Title: Int J Gynecol Cancer. Volume: 印刷中 Issue: 2 Pages: 277-281
  • DOI: 10.1136/ijgc-2018-000038
  • Peer Reviewed / Open Access
• [Journal Article] Mesenteric extraovarian Sertoli-Leydig cell tumor without DICER1 hotspot mutation: a case report. (2019)
  • Author(s): Osakabe M, Sato C, Suzuki M, Sugimoto R, Fujita Y, Uesugi N, Ishida K, Itamochi H, Baba T, Sugai T.
  • Journal Title: Diagn Pathol Volume: 印刷中 Issue: 1
  • DOI: 10.1186/s13000-019-0805-5
  • Peer Reviewed / Open Access
• [Journal Article] Clinicopathological and Molecular Findings of Differentiated-Type Minute Gastric Intramucosal Neoplasia. (2019)
  • Author(s): Uesugi N, Sugai T, Sugimoto R, Eizuka M, Fujita Y, Sato A, Osakabe M, Ishida K, Shiomi E, Toya Y, Akasaka R, Matsumoto T.
  • Journal Title: Digestion. Volume: 印刷中 Issue: 3 Pages: 287-297
  • DOI: 10.1159/000499464
  • Peer Reviewed
• [Journal Article] 今月の主題 知っておきたい十二指腸病変 主題 知っておきたい十二指腸病変の病理─腺腫,癌以外の非乳頭部病変と乳頭部腫瘍 (2018)
  • Author(s): 石田和之，永塚 真，田中義人，佐藤綾香，杉本 亮，藤田泰子，刑部光正，上杉憲幸，鳥谷洋右，梁井俊一，小穴修平，中村昌太郎，松本主之，菅井 有
  • Journal Title: 胃と腸 Volume: 53 Issue: 12 Pages: 1563-1578
  • DOI: 10.11477/mf.1403201512
  • ISSN: 0536-2180, 1882-1219
  • Year and Date: 2018-11-25
  • Peer Reviewed
• [Journal Article] 今月の主題 胃拡大内視鏡が変えたclinical practice 主題研究 1mm以下の超微小胃癌の検討 (2018)
  • Author(s): 藤田泰子，上杉憲幸，岸本光夫，山田範幸，永塚 真，杉本 亮，川崎啓祐，松本主之，土肥 統，鎌田和浩，内藤裕二，柳澤昭夫，菅井 有
  • Journal Title: 胃と腸 Volume: 53 Issue: 11 Pages: 1502-1514
  • DOI: 10.11477/mf.1403201500
  • ISSN: 0536-2180, 1882-1219
  • Year and Date: 2018-10-25
  • Peer Reviewed
• [Journal Article] 特集 大腸腫瘍の分子生物学 Ⅳ.大腸腫瘍の分子異常と病理診断 (2018)
  • Author(s): 菅井 有，永塚 真
  • Journal Title: INTESTINE Volume: 22 Issue: 5 Pages: 429-435
  • DOI: 10.19020/INT.0000000235
  • ISSN: 1883-2342, 2433-250X
  • Year and Date: 2018-09-20
  • Peer Reviewed
• [Journal Article] Budd-Chiari Syndrome and Esophageal Achalasia: Unrecognized Intrahepatic Cholangiocarcinoma Invading Multiple Organs (2018)
  • Author(s): Kakisaka K, Endo K, Sugimoto R, Ishida K, Sugai T, Takikawa Y.
  • Journal Title: Internal Medicine Volume: 57 Issue: 15 Pages: 2197-2201
  • DOI: 10.2169/internalmedicine.0448-17
  • NAID: 130007428820
  • ISSN: 0918-2918, 1349-7235
  • Year and Date: 2018-08-01
  • Peer Reviewed / Open Access
• [Journal Article] 増刊号 早期胃癌2018 ノート 胃癌遺伝子検査の現状と未来 (2018)
  • Author(s): 永塚 真，杉本 亮，藤田泰子，刑部光正，上杉憲幸，石田和之，菅井 有
  • Journal Title: 胃と腸 Volume: 53 Issue: 5 Pages: 783-788
  • DOI: 10.11477/mf.1403201375
  • ISSN: 0536-2180, 1882-1219
  • Year and Date: 2018-05-24
  • Peer Reviewed
• [Journal Article] Hepatic Angiomyolipoma Staining in the Post-vascular Phase of Contrast-enhanced Ultrasound Due to the Presence of Macrophages (2018)
  • Author(s): Endo K, Kuroda H, Kakisaka K, Oikawa T, Sawara K, Ishida K, Sugai T, Takikawa Y.
  • Journal Title: Internal Medicine Volume: 57 Issue: 9 Pages: 1247-1251
  • DOI: 10.2169/internalmedicine.9697-17
  • NAID: 130006730690
  • ISSN: 0918-2918, 1349-7235
  • Year and Date: 2018-05-01
  • Peer Reviewed / Open Access
• [Journal Article] Molecular profiling and genome-wide analysis based on somatic copy number alterations in advanced colorectal cancers (2018)
  • Author(s): Sugai T, Takahashi Y, Eizuka M, Sugimoto R, Fujita Y, Habano W, Otsuka K, Sasaki A, Yamamoto E, Matsumoto T, Suzuki H.
  • Journal Title: Molecular Carcinogenesis Volume: 57 Issue: 3 Pages: 451-461
  • DOI: 10.1002/mc.22769
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive molecular analysis based on somatic copy number alterations in intramucosal colorectal neoplasias and early invasive colorectal cancers. (2018)
  • Author(s): Sugai T, Eizuka M, Habano W, Fujita Y, Sato A, Sugimoto R, Otsuka K, Yamamoto E, Matsumoto T, Suzuki H.
  • Journal Title: Oncotarget. Volume: 9 Issue: 33 Pages: 22895-22906
  • DOI: 10.18632/oncotarget.25112
  • Peer Reviewed / Open Access
• [Journal Article] Molecular profiling and comprehensive genome-wide analysis of somatic copy number alterations in gastric intramucosal neoplasias based on microsatellite status. (2018)
  • Author(s): Sugai T, Eizuka M, Arakawa N, Osakabe M, Habano W, Fujita Y, Yamamoto E, Yamano H, Endoh M, Matsumoto T, Suzuki H.
  • Journal Title: Gastric Cancer. Volume: 21 Issue: 5 Pages: 765-775
  • DOI: 10.1007/s10120-018-0810-5
  • NAID: 40021642313
  • Peer Reviewed / Open Access
• [Journal Article] Molecular Profiling Based on KRAS/BRAF Mutation, Methylation, and Microsatellite Statuses in Serrated Lesions. (2018)
  • Author(s): Sugai T, Eizuka M, Fujita Y, Kawasaki K, Yamamoto E, Ishida K, Yamano H, Suzuki H, Matsumoto T.
  • Journal Title: Dig Dis Sci. Volume: 63 Issue: 10 Pages: 2626-2638
  • DOI: 10.1007/s10620-018-5167-4
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of the expression of cancer-associated fibroblast- and EMT-related proteins in submucosal invasive colorectal cancer. (2018)
  • Author(s): Sugai T, Uesugi N, Kitada Y, Yamada N, Osakabe M, Eizuka M, Sugimoto R, Fujita Y, Kawasaki K, Yamamoto E, Yamano H, Suzuki H, Matsumoto T.
  • Journal Title: J Cancer. Volume: 9 Issue: 15 Pages: 2702-2712
  • DOI: 10.7150/jca.25646
  • Peer Reviewed / Open Access
• [Journal Article] How to adjust endoscopic findings to histopathological findings of the stomach: a "histopathology-oriented" correspondence method helps to understand endoscopic findings (2018)
  • Author(s): Fujita Y, Kishimoto M, Dohi O, Kamada K, Majima A, Kimura-Tsuchiya R, Yagi N, Konishi H, Naito Y, Harada Y, Tanaka H, Konishi E, Sugai T, Yanagisawa A
  • Journal Title: Gastric Cancer Volume: 21 Issue: 3 Pages: 573-577
  • DOI: 10.1007/s10120-017-0762-1
  • NAID: 40021539610
  • Peer Reviewed / Open Access
• [Journal Article] Colorectal Adenocarcinoma with an Alternative Serrated Pathway. (2018)
  • Author(s): Eizuka M, Kawasaki K, Toya Y, Akasaka R, Otsuka K, Sasaki A, Matsumoto T, Sugai T.
  • Journal Title: Case Rep Gastroenterol. Volume: 12 Issue: 1 Pages: 116-124
  • DOI: 10.1159/000488192
  • Peer Reviewed / Open Access
• [Journal Article] Correlation between CT morphologic appearance and histologic findings in colorectal liver metastasis after preoperative chemotherapy. (2018)
  • Author(s): Ishida K, Tamura A, Kato K, Uesugi N, Osakabe M, Eizuka M, Hasegawa Y, Nitta H, Otsuka K, Sasaki A, Ehara S, Sugai T.
  • Journal Title: Abdom Radiol (NY). Volume: 43 Issue: 11 Pages: 2991-3000
  • DOI: 10.1007/s00261-018-1588-y
  • NAID: 120006644553
  • Peer Reviewed / Open Access
• [Journal Article] Familial Mediterranean fever mimicking Crohn disease: A case report. (2018)
  • Author(s): Asakura K, Yanai S, Nakamura S, Kawaski K, Eizuka M, Ishida K, Endo M, Sugai T, Migita K, Matsumoto T.
  • Journal Title: Medicine (Baltimore). Volume: 97 Issue: 1 Pages: e9547-e9547
  • DOI: 10.1097/md.0000000000009547
  • Peer Reviewed / Open Access
• [Journal Article] Pentalogy of Cantrell in a monozygotic twin with a giant omphalocele firmly attached to the amniotic membrane: successful prenatal diagnosis and cesarean delivery. (2018)
  • Author(s): Kanasugi T, Kikuchi A, Uesugi N, Fukagawa D, Chida H, Sasaki Y, Haba G, Isurugi C, Oyama R, Sugai T, Sugiyama T.
  • Journal Title: Congenit Anom (Kyoto). Volume: 58 Issue: 2 Pages: 73-74
  • DOI: 10.1111/cga.12237
  • Peer Reviewed / Open Access
• [Journal Article] Clinicopathological Features and Magnifying Chromoendoscopic Findings of Non-Ampullary Duodenal Epithelial Tumors. (2018)
  • Author(s): Toya Y, Endo M, Akasaka R, Urushikubo J, Gonai T, Asakura K, Yanai S, Kawasaki K, Eizuka M, Uesugi N, Nakamura S, Sugai T, Matsumoto T.
  • Journal Title: Digestion. Volume: 97 Issue: 3 Pages: 219-227
  • DOI: 10.1159/000485505
  • Peer Reviewed
• [Journal Article] Molecular characterization and pathogenesis of gastrointestinal stromal tumor. (2018)
  • Author(s): Niinuma T, Suzuki H, Sugai T.
  • Journal Title: Transl Gastroenterol Hepatol. Volume: 3 Pages: 2-2
  • DOI: 10.21037/tgh.2018.01.02
  • Peer Reviewed
• [Journal Article] Distinct Profiles of CD163-Positive Macrophages in Idiopathic Interstitial Pneumonias (2018)
  • Author(s): Yamashita M, Saito R, Yasuhira S, Fukuda Y, Sasamo H, Sugai T, Yamauchi K, Maemondo M
  • Journal Title: J Immunol Res Volume: 2018 Pages: 1436236-1436236
  • DOI: 10.1155/2018/1436236
  • Peer Reviewed / Open Access
• [Journal Article] Association between contrast-enhanced ultrasonography and histopathological findings of the metastatic lymph nodes of patients with head and neck cancer: A preliminary study. (2018)
  • Author(s): Oikawa SI, Shiga K, Saito D, Katagiri K, Ikeda A, Tuchida K, Miyaguchi J, Ishida K, Sugai T.
  • Journal Title: Oncol Lett. Volume: 15 Pages: 4171-4176
  • DOI: 10.3892/ol.2018.7835
  • Peer Reviewed / Open Access
• [Journal Article] Subtypes of the Type II Pit Pattern Reflect Distinct Molecular Subclasses in the Serrated Neoplastic Pathway. (2018)
  • Author(s): Aoki H, Yamamoto E, Yamano HO, Sugai T, Kimura T, Tanaka Y, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Nakaoka M, Yoshida Y, Harada T, Sudo G, Eizuka M, Yorozu A, Kitajima H, Niinuma T, Kai M, Nojima M, Suzuki H, Nakase H.
  • Journal Title: Dig Dis Sci. Volume: 15 Issue: 7 Pages: 1920-1928
  • DOI: 10.1007/s10620-018-5016-5
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of cancer-associated fibroblasts and the epithelial-mesenchymal transition in cutaneous basal cell carcinoma, squamous cell carcinoma and malignant melanoma (2018)
  • Author(s): Sasaki K, Sugai T, Ishida K, Osakabe M, Amano H, Kimura H, Sakuraba M, Kashiwa K, Kobayashi S
  • Journal Title: Hum Pathol Volume: - Pages: 1-8
  • DOI: 10.1016/j.humpath.2018.03.006
  • Peer Reviewed / Open Access
• [Journal Article] Collagenous Gastritis Observed by Magnifying Narrow-Band Imaging Endoscopy. (2018)
  • Author(s): Kawasaki K, Fujita Y, Uesugi N, Sugai T, Matsumoto T.
  • Journal Title: J Gastrointestin Liver Dis. Volume: 27 Issue: 1 Pages: 7-7
  • DOI: 10.15403/jgld.2014.1121.271.kaw
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease (2018)
  • Author(s): Kakisaka Keisuke、Suzuki Yuji、Fujiwara Yudai、Abe Tamami、Yonezawa Miki、Kuroda Hidekatsu、Ishida Kazuyuki、Sugai Tamotsu、Takikawa Yasuhiro
  • Journal Title: Journal of Gastroenterology Volume: NA Issue: 12 Pages: 1285-1291
  • DOI: 10.1007/s00535-018-1468-9
  • Peer Reviewed / Open Access
• [Journal Article] Case of complete response to neoadjuvant therapy using nivolumab in a patient with metastatic renal cell carcinoma. (2018)
  • Author(s): Ikarashi D, Kato Y, Katagiri H, Takahara T, Uesugi N, Shiomi E, Sugimura J, Nitta H, Sugai T, Obara W.
  • Journal Title: Int J Urol. Volume: 25 Issue: 6 Pages: 630-632
  • DOI: 10.1111/iju.13590
  • Peer Reviewed / Open Access
• [Journal Article] Diminutive intramucosal invasive (Tis) sigmoid colon carcinoma. (2018)
  • Author(s): Fukami Y, Kudo SE, Miyachi H, Misawa M, Wakamura K, Suzuki K, Igarashi K, Yamauchi A, Mori Y, Kudo T, Hayashi T, Katagiri A, Hamatani S, Sugai T.
  • Journal Title: Clin J Gastroenterol. Volume: 11 Issue: 5 Pages: 359-363
  • DOI: 10.1007/s12328-018-0864-2
  • Peer Reviewed
• [Journal Article] Diffuse Cystic Malformation with Early Gastric Cancer. (2018)
  • Author(s): Toya Y, Nakamura S, Urushikubo J, Sugimoto R, Sugai T, Matsumoto T.
  • Journal Title: J Gastrointest Surg. Volume: 22 Issue: 6 Pages: 1130-1131
  • DOI: 10.1007/s11605-017-3647-z
  • Peer Reviewed
• [Journal Article] Protein expression patterns in cancer-associated fibroblasts and cells undergoing the epithelial-mesenchymal transition in ovarian cancers. (2018)
  • Author(s): Fukagawa D, Sugai T, Osakabe M, Suga Y, Nagasawa T, Itamochi H, Sugiyama T.
  • Journal Title: Oncotarget. Volume: 9 Issue: 44 Pages: 27514-27524
  • DOI: 10.18632/oncotarget.25518
  • Peer Reviewed / Open Access
• [Journal Article] Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors (2018)
  • Author(s): Harada T、Yamamoto E、Yamano HO、Aoki H、Matsushita HO、Yoshikawa K、Takagi R、Harada E、Tanaka Y、Yoshida Y、Eizuka M、Yorozu A、Sudo G、Kitajima H、Niinuma T、Kai M、Sasaki Y、Tokino Takashi、Sugai T、Nakase H、Suzuki H
  • Journal Title: Journal of Gastroenterology Volume: 53 Issue: 12 Pages: 1241-1252
  • DOI: 10.1007/s00535-018-1481-z
  • Peer Reviewed / Open Access
• [Journal Article] Coexistence of early cancer and mucosa-associated lymphoid tissue lymphoma in Helicobacter pylori-eradicated stomach. (2018)
  • Author(s): Toya Y, Nakamura S, Fujita Y, Sugai T, Matsumoto T.
  • Journal Title: Gastrointest Endosc. Volume: 88 Issue: 5 Pages: 877-878
  • DOI: 10.1016/j.gie.2018.07.011
  • Peer Reviewed
• [Journal Article] Autoimmune hepatitis following influenza virus vaccination: Two case reports. (2018)
  • Author(s): Sasaki T, Suzuki Y, Ishida K, Kakisaka K, Abe H, Sugai T, Takikawa Y.
  • Journal Title: Medicine (Baltimore). Volume: 97 Issue: 30 Pages: e11621-e11621
  • DOI: 10.1097/md.0000000000011621
  • Peer Reviewed / Open Access
• [Journal Article] Screening for long noncoding RNAs associated with oral squamous cell carcinoma reveals the potentially oncogenic actions of DLEU1 (2018)
  • Author(s): Nishiyama K、Maruyama R、Niinuma T、Kai M、Kitajima H、Toyota M、Hatanaka Y、Igarashi T、Kobayashi J、Ogi K、Dehari H、Miyazaki A、Yorozu A、Yamamoto E、Idogawa M、Sasaki Y、Sugai T、Tokino Takashi、Hiratsuka H、Suzuki H
  • Journal Title: Cell Death & Disease Volume: 9 Issue: 8 Pages: 826-826
  • DOI: 10.1038/s41419-018-0893-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The B-Mode Image-Guided Ultrasound Attenuation Parameter Accurately Detects Hepatic Steatosis in Chronic Liver Disease. (2018)
  • Author(s): Fujiwara Y, Kuroda H, Abe T, Ishida K, Oguri T, Noguchi S, Sugai T, Kamiyama N, Takikawa Y.
  • Journal Title: Ultrasound Med Biol. Volume: 44 Issue: 11 Pages: 2223-2232
  • DOI: 10.1016/j.ultrasmedbio.2018.06.017
  • Peer Reviewed / Open Access
• [Journal Article] Gastrointestinal: Idiopathic myointimal hyperplasia of mesenteric veins. (2018)
  • Author(s): Gonai T, Toya Y, Nakamura S, Kawasaki K, Yanai S, Fujita Y, Uesugi N, Kimura T, Otsuka K, Sugai T, Matsumoto T.
  • Journal Title: J Gastroenterol Hepatol. Volume: 33 Issue: 12 Pages: 1939-1939
  • DOI: 10.1111/jgh.14384
  • Peer Reviewed
• [Journal Article] Immunohistochemical differentiation between chronic enteropathy associated with SLCO2A1 gene and other inflammatory bowel diseases. (2018)
  • Author(s): Yamaguchi S, Yanai S, Nakamura S, Kawasaki K, Eizuka M, Uesugi N, Sugai T, Umeno J, Esaki M, Matsumoto T.
  • Journal Title: Intest Res. Volume: 16 Issue: 3 Pages: 393-399
  • DOI: 10.5217/ir.2018.16.3.393
  • Peer Reviewed / Open Access
• [Journal Article] A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer. (2018)
  • Author(s): Kato Y, Zembutsu H, Takata R, Matsuura T, Kato R, Kanehira M, Iwasaki K, Yamada N, Katagiri T, Sugai T, Fujioka T, Nakamura Y, Obara W.
  • Journal Title: Oncol Lett. Volume: 16 Pages: 5775-5784
  • DOI: 10.3892/ol.2018.9330
  • NAID: 120007099372
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Practical fecal calprotectin cut-off value for Japanese patients with ulcerative colitis. (2018)
  • Author(s): Urushikubo J, Yanai S, Nakamura S, Kawasaki K, Akasaka R, Sato K, Toya Y, Asakura K, Gonai T, Sugai T, Matsumoto T.
  • Journal Title: World J Gastroenterol. Volume: 24 Issue: 38 Pages: 4384-4392
  • DOI: 10.3748/wjg.v24.i38.4384
  • Peer Reviewed / Open Access
• [Journal Article] 発生部位に基づいた大腸癌の臨床病理学的，分子病理学的差異． (2018)
  • Author(s): 菅井 有
  • Journal Title: 病理と臨床 Volume: 36 Pages: 1059-1066
  • Peer Reviewed
• [Journal Article] 画像診断との対比で学ぶ 大腸疾患アトラス IBD（UC）と癌． (2018)
  • Author(s): 永塚 真，川崎啓祐，梁井俊一，松本主之，菅井 有
  • Journal Title: 大腸がん perspective Volume: 4 Pages: 6-10
  • Peer Reviewed
• [Journal Article] Genetic differences stratified by PCR-based microsatellite analysis in gastric intramucosal neoplasia. (2017)
  • Author(s): Sugai T, Sugimoto R, Habano W, Endoh M, Eizuka M, Tsuchida K, Yamamoto E, Kawasaki K, Yanai S, Matsumoto T, Suzuki H.
  • Journal Title: Gastric Cancer. Volume: 20 Issue: 2 Pages: 286-296
  • DOI: 10.1007/s10120-016-0616-2
  • NAID: 40021129465
  • Peer Reviewed / Open Access
• [Journal Article] Molecular subtypes of colorectal cancers determined by PCR-based analysis. (2017)
  • Author(s): Sugai T, Eizuka M, Takahashi Y, Fukagawa T, Habano W, Yamamoto E, Akasaka R, Otuska K, Matsumoto T, Suzuki H.
  • Journal Title: Cancer Sci Volume: 108(3) Issue: 3 Pages: 427-434
  • DOI: 10.1111/cas.13164
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of molecular alterations in laterally spreading tumors of the colorectum. (2017)
  • Author(s): Sugai T, Habano W, Takagi R, Yamano H, Eizuka M, Arakawa N, Takahashi Y, Yamamoto E, Kawasaki K, Yanai S, Ishida K, Suzuki H, Matsumoto T.
  • Journal Title: J Gastroenterol Volume: 52 Issue: 6 Pages: 715-723
  • DOI: 10.1007/s00535-016-1269-y
  • NAID: 110006550042
  • Peer Reviewed / Open Access
• [Journal Article] A case of intravascular papillary endothelial hyperplasia of the stomach leading to a novel hypothesis for the pathogenesis. (2017)
  • Author(s): Eizuka M, Tsuchida K, Sugimoto R, Ishida K, Uesugi N, Yanai S, Akasaka R, Toya Y, Kawasaki K, Nakamura S, Matsumoto T, Sugai T.
  • Journal Title: Histopathology. Volume: 70 Issue: 4 Pages: 672-674
  • DOI: 10.1111/his.13093
  • Peer Reviewed / Open Access
• [Journal Article] Vascular Invasion and Stromal S100A4 Expression at the Invasive Front of Colorectal Cancer are Novel Determinants and Tumor Prognostic Markers (2017)
  • Author(s): Sugai, T. Yamada, N. Eizuka, M. Sugimoto, R. Uesugi, N. Osakabe, M. Ishida, K. Otsuka, K. Sasaki, A. Matsumoto, T.
  • Journal Title: J Cancer Volume: 8 Issue: 9 Pages: 1552-1561
  • DOI: 10.7150/jca.18685
  • Peer Reviewed / Open Access
• [Journal Article] Clinicopathological and molecular stability and methylation analyses of gastric papillary adenocarcinoma (2017)
  • Author(s): Uesugi, N. Sugai, T. Sugimoto, R. Eizuka, M. Fujita, Y. Sato, A. Osakabe, M. Ishida, K. Koeda, K. Sasaki, A. Matsumoto, T.
  • Journal Title: Pathology Volume: 49 Issue: 6 Pages: 596-603
  • DOI: 10.1016/j.pathol.2017.07.004
  • Peer Reviewed
• [Journal Article] Molecular alterations in colorectal adenomas and intramucosal adenocarcinomas defined by high-density single-nucleotide polymorphism arrays. (2017)
  • Author(s): Eizuka M, Sugai T, Habano W, Uesugi N, Takahashi Y, Kawasaki K, Yamamoto E, Suzuki H, Matsumoto T.
  • Journal Title: J Gastroenterol Volume: - Issue: 11 Pages: 1158-1168
  • DOI: 10.1007/s00535-017-1317-2
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa. (2017)
  • Author(s): Sugai T, Yoshida M, Eizuka M, Uesugii N, Habano W, Otsuka K, Sasaki A, Yamamoto E, Matsumoto T, Suzuki H.
  • Journal Title: Clin Epigenetics. Volume: 55 Issue: 1 Pages: 55-55
  • DOI: 10.1186/s13148-017-0352-4
  • Peer Reviewed / Open Access
• [Journal Article] Tumor budding at the invasive front of colorectal cancer may not be associated with the epithelial-mesenchymal transition. (2017)
  • Author(s): Yamada N, Sugai T, Eizuka M, Tsuchida K, Sugimoto R, Mue Y, Suzuki M, Osakabe M, Uesugi N, Ishida K, Otsuka K, Matsumoto T.
  • Journal Title: Hum Pathol. Volume: 60 Pages: 151-159
  • DOI: 10.1016/j.humpath.2016.10.007
  • Peer Reviewed / Open Access
• [Journal Article] Case of gastric neuroendocrine carcinoma showing an interesting tumorigenic pathway. (2017)
  • Author(s): Uesugi N, Sugimoto R, Eizuka M, Fujita Y, Osakabe M, Koeda K, Kosaka T, Yanai S, Ishida K, Sasaki A, Matsumoto T, Sugai T.
  • Journal Title: World J Clin Cases. Volume: 5 Issue: 11 Pages: 397-402
  • DOI: 10.12998/wjcc.v5.i11.397
  • Peer Reviewed / Open Access
• [Journal Article] Genome-wide analysis of DNA copy number alterations in early and advanced gastric cancers. (2017)
  • Author(s): Arakawa N, Sugai T, Habano W, Eizuka M, Sugimoto R, Akasaka R, Toya Y, Yamamoto E, Koeda K, Sasaki A, Matsumoto T, Suzuki H.
  • Journal Title: Mol Carcinog. Volume: 56 Issue: 2 Pages: 527-537
  • DOI: 10.1002/mc.22514
  • Peer Reviewed / Open Access
• [Journal Article] Expression of cell cycle-related proteins in oropharyngeal squamous cell carcinoma based on human papilloma virus status (2017)
  • Author(s): Tsuchida, K. Sugai, T. Uesugi, N. Ishida, K. Matsuura, K. Sato, I. Shiga, K. Sato, H.
  • Journal Title: Oncol Rep Volume: 38 Issue: 2 Pages: 908-916
  • DOI: 10.3892/or.2017.5720
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy of Everolimus for Treating Renal Angiomyolipoma with Inferior Vena Cava Thrombus Associated with Tuberous Sclerosis: A Case Report. (2017)
  • Author(s): Ikarashi D, Mue Y, Shiomi E, Takayama M, Kato R, Kato Y, Ishida K, Abe T, Sugai T, Obara W.
  • Journal Title: Urol Case Rep. Volume: 11 Pages: 11-13
  • DOI: 10.1016/j.eucr.2016.12.003
  • Peer Reviewed / Open Access
• [Journal Article] Inhibition of Aurora Kinase A Synergistically Enhances Cytotoxicity in Ovarian Clear Cell Carcinoma Cell Lines Induced by Cisplatin: A Potential Treatment Strategy. (2017)
  • Author(s): Chiba Y, Sato S, Itamochi H, Yoshino N, Fukagawa D, Kawamura H, Suga Y, Kojima-Chiba A, Muraki Y, Sugai T, Sugiyama T.
  • Journal Title: Int J Gynecol Cancer Volume: 8 Issue: 8 Pages: 1666-74
  • DOI: 10.1097/igc.0000000000001081
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer. (2017)
  • Author(s): Kai M, Yamamoto E, Sato A, Yamano HO, Niinuma T, Kitajima H, Harada T, Aoki H, Maruyama R, Toyota M, Hatahira T, Nakase H, Sugai T, Yamashita T, Toyota M, Suzuki H.
  • Journal Title: Mol Carcinog Volume: - Issue: 7 Pages: 1743-1752
  • DOI: 10.1002/mc.22631
  • Peer Reviewed / Open Access
• [Journal Article] Gastrointestinal mantle cell lymphoma with isolated mass and multiple lymphomatous polyposis: report of two cases. (2017)
  • Author(s): Yanai S, Nakamura S, Yamaguchi S, Kawasaki K, Ishida K, Sugai T, Umeno J, Esaki M, Matsumoto T.
  • Journal Title: Clin J Gastroenterol. Volume: 10 Issue: 4 Pages: 327-330
  • DOI: 10.1007/s12328-017-0740-5
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of PI3K mutations and PI3K pathway proteins in advanced gastric cancer (2017)
  • Author(s): Ito C, Nishizuka SS, Ishida K, Uesugi N, Sugai T, Tamura G, Koeda K, Sasaki A
  • Journal Title: Journal of Surgical Research Volume: 212 Pages: 195-204
  • DOI: 10.1016/j.jss.2017.01.018
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Endoscopic and Molecular Characterization of Colorectal Sessile Serrated Adenoma/polyps with Cytological Dysplasia. (2017)
  • Author(s): Tanaka Y, Yamano HO, Yamamoto E, Matushita HO, Aoki H, Yoshikawa K, Takagi R, Harada E, Nakaoka M, Yoshida Y, Eizuka M, Sugai T, Suzuki H, Nakase H.
  • Journal Title: Gastrointest Endosc. Volume: 86 Issue: 6 Pages: 1131-1138
  • DOI: 10.1016/j.gie.2017.05.006
  • Peer Reviewed / Open Access
• [Journal Article] Phase I clinical trial of cell division associated 1 (CDCA1) peptide vaccination for castration resistant prostate cancer. (2017)
  • Author(s): Obara W, Sato F, Takeda K, Kato R, Kato Y, Kanehira M, Takata R, Mimata H, Sugai T, Nakamura Y, Fujioka T.
  • Journal Title: Cancer Sci. Volume: 108 Issue: 7 Pages: 1452-1457
  • DOI: 10.1111/cas.13278
  • Peer Reviewed / Open Access
• [Journal Article] Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors. (2017)
  • Author(s): Niinuma T, Kai M, Kitajima H, Yamamoto E, Harada T, Maruyama R, Nobuoka T, Kanda T, Hasegawa T, Tokino T, Sugai T, Shimomura Y, Nakase H, Suzuki H
  • Journal Title: Oncology Letters Volume: 14 Pages: 5703-5710
  • DOI: 10.3892/ol.2017.6911
  • Peer Reviewed / Open Access
• [Journal Article] A case of a "wandering" mobile solitary fibrous tumor occurring in the pancreas. (2017)
  • Author(s): Oana S, Matsuda N, Sibata S, Ishida K, Sugai T, Matsumoto T.
  • Journal Title: Clin J Gastroenterol. Volume: 10 Issue: 6 Pages: 535-540
  • DOI: 10.1007/s12328-017-0774-8
  • Peer Reviewed / Open Access
• [Journal Article] Association between white opaque substance under magnifying colonoscopy and lipid droplets in colorectal epithelial neoplasms (2017)
  • Author(s): Kawasaki, K. Eizuka, M. Nakamura, S. Endo, M. Yanai, S. Akasaka, R. Toya, Y. Fujita, Y. Uesugi, N. Ishida, K. Sugai, T. Matsumoto, T.
  • Journal Title: World J Gastroenterol Volume: 23 Issue: 47 Pages: 8367-8375
  • DOI: 10.3748/wjg.v23.i47.8367
  • Peer Reviewed / Open Access
• [Journal Article] Sporadic breast metastasis derived from renal cell carcinoma: A case report. (2017)
  • Author(s): Ikarashi D, Ishida K, Kashiwaba M, Kato Y, Shiomi E, Takayama M, Komatsu H, Takata R, Ohmori S, Sugai T, Obara W.
  • Journal Title: Urol Case Rep. Volume: 16 Pages: 126-128
  • DOI: 10.1016/j.eucr.2017.11.032
  • Peer Reviewed / Open Access
• [Journal Article] Renal pelvic cancer with spleen invasion arising in horseshoe kidney; a case report. (2017)
  • Author(s): Ito A, Kato Y, Shiomi E, Ishii S, Suzuki M, Omori S, Abe T, Tanji S, Sugai T, Obara W.
  • Journal Title: Urol Case Rep. Volume: 16 Pages: 123-125
  • DOI: 10.1016/j.eucr.2017.11.031
  • Peer Reviewed / Open Access
• [Journal Article] Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer. (2017)
  • Author(s): Aoki H, Yamamoto E, Takasawa A, Niinuma T, Yamano HO, Harada T, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Tanaka Y, Yoshida Y, Aoyama T, Eizuka M, Yorozu A, Kitajima H, Kai M, Sawada N, Sugai T, Nakase H, Suzuki H.
  • Journal Title: Oncotarget. Volume: 9 Issue: 4 Pages: 4707-4721
  • DOI: 10.18632/oncotarget.23523
  • Peer Reviewed / Open Access
• [Journal Article] Primary Intramedullary Malignant Lymphoma in the Cervical Cord with a Presyrinx State. (2017)
  • Author(s): Chida K, Sugawara A, Koji T, Beppu T, Mue Y, Sugai T, Ogasawara K.
  • Journal Title: Cureus. Volume: 9 Pages: 2006-2006
  • DOI: 10.7759/cureus.2006
  • Peer Reviewed / Open Access
• [Presentation] 大腸早期腫瘍性病変及び浸潤癌のマルチオミックス解析． (2020)
  • Author(s): 菅井 有，杉本 亮，刑部光正，永塚 真，田中義人，松本主之
  • Organizer: 第92回大腸癌研究会
• [Presentation] 大腸腫瘍（腺腫，粘膜内癌，進行癌）におけるmicro RNA 発現異常解析． (2020)
  • Author(s): 永塚 真，田中義人，佐藤綾香，杉本 亮，藤田泰子，上杉憲幸，菅井 有
  • Organizer: 第92回大腸癌研究会
• [Presentation] Traditional serrated adenoma(TSA)における臨床病理学的および分子生物学的検討． (2020)
  • Author(s): 田中義人，上杉憲幸，永塚 真，杉本 亮，藤田泰子，菅井 有
  • Organizer: 第92回大腸癌研究会
• [Presentation] 腺管分離法を用いた大腸腺腫，SSA/P，早期大腸癌および進行大腸癌の網羅的microRNA 解析 (2020)
  • Author(s): 杉本 亮，刑部光正，上杉憲幸，藤田泰子，永塚 真，川崎啓祐，鈴木正通，佐藤綾香，伊藤勇馬，石田和之，大塚幸喜，佐々木 章，松本主之，菅井 有
  • Organizer: 第16回日本消化管学会総会学術集会
• [Presentation] SNP array を用いた早期胃癌，進行胃癌における染色体コピー数変化の網羅的解析． (2020)
  • Author(s): 永塚 真，荒川典之，田中義人，杉本 亮，藤田泰子，鳥谷洋右，赤坂理三郎，川崎啓祐，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: 第16回日本消化管学会総会学術集会
• [Presentation] 大腸鋸歯状病変の癌化と分子異常． (2019)
  • Author(s): 菅井 有
  • Organizer: 第108回日本病理学会総会．
  • Invited
• [Presentation] 食道に発生したWarthin tumorの一例． (2019)
  • Author(s): 石田和之，杉本 亮，永塚 真，西谷匡央，鈴木正通，藤田泰子，刑部光正，上杉憲幸，萱場尚一，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 腺窩上皮型胃癌の臨床病理学的および分子病理学的検討． (2019)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，藤田泰子，刑部光正，石田和之，松本主之， 菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 女性生殖器の発生を考慮した転写因子に基づく卵巣癌の新規分類の試み． (2019)
  • Author(s): 刑部光正，佐藤千絵，杉本 亮，鈴木正通，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 手繋ぎ型早期胃癌の臨床病理学的および分子病理学的検討． (2019)
  • Author(s): 藤田泰子，上杉憲幸，杉本 亮，永塚 真，佐藤綾香，刑部光正，石田和之, ，鳥谷洋右，松本主之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 確定診断困難な胃粘膜下病変の1例 (2019)
  • Author(s): 杉本 亮，上杉憲幸，刑部光正，秋山有史，佐々木 章，松本主之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 大腸癌と同時に発見された肺腸型腺癌の一例 (2019)
  • Author(s): 西谷匡央，石田和之，刑部光正，佐藤綾香，杉本 亮，藤田泰子，阿保亜紀子，上杉憲幸，佐藤 孝，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 食道表在癌における免疫組織化学染色による細胞周期関連蛋白発現の検討． (2019)
  • Author(s): 永塚 真，上杉憲幸，田中義人，杉本 亮，藤田泰子，刑部光正，石田和之，佐々木 章，松本主之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 淡明細胞型腎細胞癌におけるmicroRNAの検討． (2019)
  • Author(s): 塩見 叡，石田和之，刑部光正，露久保敬嗣，山田範幸，上杉憲幸，高田 亮, 杉村 淳，小原 航，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 大腸進行癌の分離癌腺管および癌間質におけるmicroRNAの発現解析． (2019)
  • Author(s): 佐藤綾香，藤田泰子，杉本 亮，永塚 真，刑部光正，上杉憲幸，大塚幸喜，石田和之，佐々木 章，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] Traditional serrated adenoma（TSA）における臨床病理学的および分子生物学的検討． (2019)
  • Author(s): 田中義人，上杉 憲幸，山田 範幸，永塚 真，杉本 亮，藤田 泰子，刑部 光正，石田 和之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 腎細胞癌における copy number alteration (CNA) の網羅的解析． (2019)
  • Author(s): 露久保敬嗣，石田和之，塩見 叡，永塚 真，刑部光正，上杉 憲幸，高田 亮，杉村 淳，小原 航，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 小腸間膜に発生した中分化型Sertoli - Leydig cell tumorの一例． (2019)
  • Author(s): 佐藤千絵，刑部光正，西谷匡央，鈴木正通，杉本 亮，藤田泰子，上杉憲幸，石田和之，馬場 長，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 大腸粘膜下層癌における微小環境形成関連タンパク発現因子の解析． (2019)
  • Author(s): 山田範幸，刑部光正，永塚 真，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第108回日本病理学会総会
• [Presentation] 子宮体癌におけるmismatch repair蛋白の発現異常とMSIの検討． (2019)
  • Author(s): 刑部光正，佐藤千絵，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第60回日本臨床細胞学会総会春期大会
• [Presentation] 結節性リンパ球優位型Hodgkinリンパ腫の一例． (2019)
  • Author(s): 菊池いな子，刑部光正，高橋静子，山田範幸，安保淳一，阿保亜紀子，上杉憲幸，石田和之，佐藤 孝，菅井 有
  • Organizer: 第60回日本臨床細胞学会総会春期大会
• [Presentation] Analysis of expression patterns of microRNAs in ovarian high-grade serous carcinoma. (2019)
  • Author(s): Sato C, Osakabe M, Ito Y, Sato A, Nishiya M, Suzuki S, Sugimoto R, Fujita Y, Uesugi N, Ishida K, Baba T, Sugai T
  • Organizer: The 38th Sapporo International Cancer Symposium（第38回札幌国際がんシンポジウム
  • Int'l Joint Research
• [Presentation] 表在性非乳頭部十二指腸腫瘍(SNADET) (2019)
  • Author(s): 菅井 有
  • Organizer: 第13回日本消化管学会教育集会
  • Invited
• [Presentation] Traditional serrated adenoma(TSA)における臨床病理学的および生物学的検討． (2019)
  • Author(s): 田中義人，上杉憲幸，山田範幸，永塚 真，佐藤綾香，鈴木正通，杉本 亮，藤田泰子，刑部光正，石田和之，川崎啓祐，松本主之，菅井 有
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 腺窩上皮型胃癌における臨床病理学的および分子生物学的解析． (2019)
  • Author(s): 上杉憲幸，杉本 亮，永塚 真，藤田泰子，刑部光正，石田和之，松本主之，菅井 有
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 大腸腫瘍（腺腫，早期癌，進行癌）におけるmicroRNA発現異常の解析． (2019)
  • Author(s): 永塚 真，田中義人，杉本 亮，藤田泰子，佐藤綾香，刑部光正，上杉憲幸，石田和之，佐々木 章，松本主之，菅井 有
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 腺管分離法を用いた大腸癌浸潤部における癌腺管および周囲間質細胞の網羅的microRNA解析． (2019)
  • Author(s): 杉本 亮，刑部光正，上杉憲幸，永塚 真，佐藤綾香，藤田泰子，鈴木正通，石田和之，大塚幸喜，佐々木 章，菅井 有
  • Organizer: 第78回日本癌学会学術総会
• [Presentation] 分離腺管を用いた大腸粘膜内腫瘍と大腸癌のオミックス解析 -Gland based geneticsの提唱-． (2019)
  • Author(s): 菅井 有
  • Organizer: 第65回日本病理学会秋期特別総会
  • Invited
• [Presentation] 手繋ぎ型早期胃癌における臨床病理学的および分子病理学的特徴． (2019)
  • Author(s): 藤田泰子，上杉憲幸，杉本 亮，永塚 真，佐藤綾香，伊藤勇馬，刑部光正，石田和之，松本主之，菅井 有
  • Organizer: 第65回日本病理学会秋期特別総会
• [Presentation] 腺管分離法を用いた大腸癌腺管および周囲間質の網羅的messenger RNA解析． (2019)
  • Author(s): 杉本 亮，刑部光正，上杉憲幸，山田範幸，永塚 真，佐藤綾香，石田和之，大塚幸喜，佐々木 章，菅井 有
  • Organizer: 第65回日本病理学会秋期特別総会
• [Presentation] 発生部位に基づいたmicrosatellite stable型大腸癌における臨床病理学的、分子病理学的解析． (2018)
  • Author(s): 菅井 有，高橋弥生，永塚 真
  • Organizer: 第88回大腸癌研究会
• [Presentation] 大腸粘膜下層浸潤癌における癌関連線維芽細胞および上皮間葉転換関連蛋白の免疫組織化学的検討 (2018)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，藤田泰子，刑部光正，大塚幸喜，石田和之，菅井 有
  • Organizer: 第88回大腸癌研究会
• [Presentation] 腺管分離材料を用いた大腸癌の予後因子の検討． (2018)
  • Author(s): 杉本 亮，上杉憲幸，刑部光正，吉田雅一，赤坂理三郎，大塚幸喜，佐々木 章，松本主之，菅井 有
  • Organizer: 第88回大腸癌研究会
• [Presentation] 大腸粘膜下層浸潤癌における癌関連線維芽細胞および上皮間葉転換関連蛋白の免疫組織化学的検討． (2018)
  • Author(s): 上杉憲幸，山田範幸，永塚 真，杉本 亮，藤田泰子，刑部光正，大塚幸喜，石田和之，佐々木 章，菅井 有
  • Organizer: 第14回日本消化管学会総会学術集会
• [Presentation] 分化型粘膜下層浸潤胃癌における簇出とリンパ節転移の検討． (2018)
  • Author(s): 杉本 亮，菅井 有，松本主之，佐々木 章
  • Organizer: 第14回日本消化管学会総会学術集会
• [Presentation] SNP arrayを用いた大腸腺腫、粘膜内癌における分子学的変化． (2018)
  • Author(s): 永塚 真，杉本 亮，藤田泰子，鳥谷洋右，川崎啓祐，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: 第14回日本消化管学会総会学術集会
• [Presentation] 消化管病理医からみた消化管家族性腫瘍の病理と分子異常． (2018)
  • Author(s): 菅井 有
  • Organizer: 第24回日本家族性腫瘍学会学術集会
  • Invited
• [Presentation] Recent Advances in Molecular Carcinogesis of Colorectal Carcinoma. (2018)
  • Author(s): Sugai T
  • Organizer: Maastricht Pathology 2018（英国病理学会のマーストリヒト大会2018）
  • Int'l Joint Research / Invited
• [Presentation] 肝門部領域胆管癌と遠位胆管癌における粘液形質に基づく分類の比較およびその意義． (2018)
  • Author(s): 石田和之，田井誠悟，永塚 真，山田範幸，千田喜子，杉本 亮，藤田泰子，刑部光正，上杉憲幸，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 腺窩上皮型胃癌の臨床病理学的および免疫組織化学的検討． (2018)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，山田範幸，佐藤綾香，藤田泰子，刑部光正，石田和之，松本主之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 子宮体部癌肉腫における上皮間葉転換関連蛋白発現の免疫組織化学的検討． (2018)
  • Author(s): 刑部光正，深川大輔，鈴木正通，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 内視鏡的切除検体における超微小胃癌の臨床病理学的特徴． (2018)
  • Author(s): 藤田泰子，上杉憲幸，山田範幸，杉本 亮，刑部光正，石田和之，岸本光夫，小西英一，柳澤昭夫，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 腺管分離法を用いた大腸癌の予後因子の検討． (2018)
  • Author(s): 杉本 亮，上杉憲幸，刑部光正，大塚幸喜，佐々木 章，松本主之，山田範幸，永塚 真，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 皮膚悪性腫瘍における癌関連線維芽細胞および上皮間葉転換の解析． (2018)
  • Author(s): 佐々木孝輔，石田和之，山田範幸，刑部光正，上杉憲幸，木村裕明，天野博雄，櫻庭 実，小林誠一郎，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 卵巣癌における癌関連線維芽細胞およびEMT関連蛋白の免疫組織化学的検討． (2018)
  • Author(s): 深川大輔，刑部光正，佐藤千絵，山田範幸，上杉憲幸，石田和之，板持広明，杉山 徹，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 大腸進行癌におけるmicroRNA発現の解析． (2018)
  • Author(s): 佐藤綾香，石田和之，藤田泰子，杉本 亮，刑部光正，上杉憲幸，大塚幸喜，佐々木 章，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 腎細胞癌におけるmicro RNAの検討． (2018)
  • Author(s): 塩見 叡，石田和之，山田範幸，刑部光正，上杉憲幸，高田 亮，大森 聡，小原 航，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 肺癌組織分類に有用な免疫組織化学染色の検討． (2018)
  • Author(s): 菊池いな子，佐藤彩佳，山田範幸，杉本 亮，藤田泰子，刑部光正，上杉憲幸，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 大腸粘膜下層癌におけるリンパ節転移関連因子の解析． (2018)
  • Author(s): 山田範幸，永塚 真，杉本 亮，藤田泰子，刑部光正，上杉憲幸，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 全身の諸臓器に生じる癌腫の鑑別に有用な免疫染色パネルの検討． (2018)
  • Author(s): 佐藤彩佳，刑部光正，山田範幸，菊池いな子，佐藤綾香，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] Mesenteric inflammatory veno-occlusive disease (MIVOD)を来たした2例． (2018)
  • Author(s): 千田喜子，田井誠悟，石田和之，山田範幸，永塚 真，杉本 亮，藤田泰子，刑部光正，上杉憲幸，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 類表皮嚢胞に生じた扁平上皮癌の一例． (2018)
  • Author(s): 工藤正裕，刑部光正，無江良晴，鈴木正通，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第107回日本病理学会総会
• [Presentation] 各種タンパクの原発巣と転移巣における発現差異の検討． (2018)
  • Author(s): 佐藤彩佳，刑部光正，菊池いな子，山田範幸，佐藤綾香，杉本 亮，藤田泰子，上杉憲幸，石田和之，菅井 有
  • Organizer: 第27回日本がん転移学会学術集会・総会
• [Presentation] SNP array を用いた大腸腺腫、粘膜内癌における分子学的変化． (2018)
  • Author(s): 永塚 真，杉本 亮，藤田泰子，川崎啓祐，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] 超微小胃癌の特徴． (2018)
  • Author(s): 藤田泰子，上杉憲幸，刑部光正，柳澤昭夫，菅井 有
  • Organizer: 第77回日本癌学会学術総会
• [Presentation] 大腸腫瘍の病理診断と分子異常． (2018)
  • Author(s): 菅井 有
  • Organizer: 第36回日本大腸検査学会総会
  • Invited
• [Presentation] SNP arrayを用いた早期胃癌, 進行胃癌における染色体コピー数変化の網羅解析 (2018)
  • Author(s): 永塚 真，荒川典之，杉本 亮，藤田泰子，鳥谷洋右，赤坂理三郎，川崎啓祐，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: JDDW2018
• [Presentation] 腺管分離法を用いた大腸腫瘍における分子解析． (2018)
  • Author(s): 菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
  • Invited
• [Presentation] 膵退形成癌（未分化癌）における上皮間葉転換関連蛋白の発現について． (2018)
  • Author(s): 石田和之，刑部光正，山田範幸，杉本 亮，藤田泰子，上杉憲幸，藤島史喜，鈴木博義，澤井高志，菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
• [Presentation] 腺窩上皮型胃癌の臨床病理学的および分子病理学的検討． (2018)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，藤田泰子，刑部光正，石田和之，松本主之，菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
• [Presentation] 内視鏡的切除検体における超微小胃癌の臨床病理学的特徴． (2018)
  • Author(s): 藤田泰子，上杉憲幸，山田範幸，永塚 真，杉本 亮，刑部光正，石田和之，岸本光夫，小西英一，松本主之，柳澤昭夫，菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
• [Presentation] 臨床病理学的および分子病理学的因子に基づいた大腸癌の予後因子の検討． (2018)
  • Author(s): 杉本 亮，上杉憲幸，刑部光正，赤坂理三郎，永塚 真，藤田泰子，石田和之，大塚幸喜，佐々木 章，菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
• [Presentation] 大腸腺腫，粘膜内癌，浸潤癌における体細胞コピー数変化に基づいたゲノムワイドな分子解析． (2018)
  • Author(s): 永塚 真，杉本 亮，藤田泰子，川崎啓祐，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: 第29回日本消化器癌発生学会総会
• [Presentation] 尿細胞診における紡錘形細胞の意義に関する検討． (2018)
  • Author(s): 肥田野 靖史，石田和之，佐藤彩佳，上田奈央子，高橋静子，菊池いな子，山田範幸，安保淳一，佐藤綾香，鈴木正通，杉本 亮，藤田泰子，刑部光正， 上杉憲幸，菅井 有
  • Organizer: 第57回日本臨床細胞学会秋期大会
• [Presentation] Recent Advances in Molecular Carcinogesis of Colorectal Carcinoma. (2018)
  • Author(s): Sugai T
  • Organizer: Maastricht Pathology 2018
  • Int'l Joint Research / Invited
• [Presentation] 大腸粘膜下層浸潤癌における癌関連線維芽細胞および上皮間葉転換関連蛋白の免疫組織化学的検討． (2018)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，藤田泰子，刑部光正，大塚幸喜，石田和之，菅井 有
  • Organizer: 第88回大腸癌研究会
• [Presentation] 分化型粘膜下層浸潤胃癌における簇出とリンパ節転移の検討． (2018)
  • Author(s): 杉本 亮，菅井 有，松本主之，佐々木 章．
  • Organizer: 第14回日本消化管学会総会学術集会
• [Presentation] Clinicopathological analysis of foveolar-type gastric adenocarcinoma． (2018)
  • Author(s): 上杉憲幸，永塚 真，杉本 亮，藤田泰子，松本主之，菅井 有
  • Organizer: 第90回日本胃癌学会総会
• [Presentation] 大腸腫瘍における病理診断と分子異常 消化器内科医と病理医の新しい連携-． (2017)
  • Author(s): 菅井 有
  • Organizer: 第203回日本消化器病学会東北支部例会/第159回日本消化器内視鏡学会東北支部例会
  • Invited
• [Presentation] 上皮成分に種々の化生を伴う子宮体部腺肉腫の一例． (2017)
  • Author(s): 深川大輔，刑部光正，山田範幸，深川智之，菅 安寿子，古武陽子，佐藤誠也，千葉淳美，上杉憲幸，石田和之，板持広明，杉山 徹，菅井 有
  • Organizer: 第59回日本婦人科腫瘍学会学術講演会
• [Presentation] 早期胃癌・進行胃癌におけるゲノムワイドなDNAコピー数変化解析． (2017)
  • Author(s): 永塚 真，荒川典之，杉本 亮，藤田泰子，鳥谷洋右，赤坂理三郎，刑部光正，上杉憲幸，石田和之，肥田圭介，佐々木 章，松本主之，菅井 有
  • Organizer: 第76回日本癌学会学術総会
• [Presentation] 分化型粘膜下層浸潤胃癌における簇出とリンパ節転移の検討． (2017)
  • Author(s): 杉本 亮，上杉憲幸，永塚 真，山田範幸，刑部光正，石田和之，松本主之，菅井 有
  • Organizer: 第28回日本消化器癌発生学会総会
• [Presentation] SNP arrayを用いた大腸腺腫，粘膜内癌における分子学的変化． (2017)
  • Author(s): 永塚 真，川崎啓祐，杉本 亮，佐藤綾香，藤田泰子，刑部光正，上杉憲幸，石田和之，松本主之，菅井 有
  • Organizer: 第28回日本消化器癌発生学会総会
• [Remarks] 岩手医科大学医学部病理診断学講座
  • URL: https://pathology-iwate-med.jp
• [Remarks] 岩手医科大学病理診断学講座
  • URL: https://pathology-iwate-med.jp