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Development of compressed sensing based iterative reconstruction for SPECT image

Research Project

Project/Area Number 17K09069
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionKyorin University

Principal Investigator

Matsutomo Norikazu  杏林大学, 保健学部, 講師 (90781237)

Co-Investigator(Kenkyū-buntansha) 橋本 雄幸  杏林大学, 保健学部, 教授 (30269542)
山本 智朗  杏林大学, 保健学部, 教授 (30433600)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2018: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Keywords圧縮センシング / 画像再構成法 / 核医学 / 放射性同位元素 / オフセットサンプリング / 短時間収集 / ドパミントランスポータSPECT / 画像再構成 / SPECT
Outline of Final Research Achievements

Compressed sensing (CS) is a signal processing technique that was initially proposed for sparse signal recovery. We developed CS-based iterative reconstruction from under-sampled projection data in SPECT, and evaluated the quality and quantification of SPECT images obtained by CS-based iterative reconstruction (CS-IR) using digital mathematical and striatal numerical phantoms. As a result, CS-IR could allow a reduction in the number of projections without decreasing the image quality and quantification, could help to reduce overall acquisition time in SPECT imaging.

Academic Significance and Societal Importance of the Research Achievements

虚血性心疾患や認知症,パーキンソン病などの診断に広く用いられているSPECT画像は,非常に少ない信号量で構築されるため,診断に適した画像を得るために撮像時間が長くなるという欠点を持つ.撮像時間を短くすることは患者の利便性を向上させるが,その結果として画質が大きく劣化することになる.本研究で開発した画像再構成法は画質を低下させることなく撮像時間を1/10まで短縮することが可能であり,患者の利便性のみならず検査をより価値あるものにできたと考える.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (4 results)

All 2020 2019 2018 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Performance of compressed sensing-based iterative reconstruction for single-photon emission computed tomography from undersampled projection data2019

    • Author(s)
      Matsutomo Norikazu、Fukaya Kaoru、Hashimoto Takeyuki、Yamamoto Tomoaki、Sato Eisuke
    • Journal Title

      Nuclear Medicine Communications

      Volume: 40 Issue: 2 Pages: 106-114

    • DOI

      10.1097/mnm.0000000000000938

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] オフセットサンプリングと圧縮センシングを用いた少数投影データからのSPECT画像再構成2020

    • Author(s)
      松友紀和,橋本雄幸,山本智朗
    • Organizer
      第76回日本放射線技術学会総会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Reduced acquisition time or activity does for 123I-FP-CIT SPECT with compressed sensing-based iterative reconstruction2018

    • Author(s)
      Norikazu Matsutomo, Takeyuki Hashimoto, Tomoaki Yamamoto
    • Organizer
      SNMMI 2018 Annual Meeting
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Validation of compressed sensing-based iterative reconstruction algorithm in dopamine transporter SPECT2017

    • Author(s)
      松友紀和
    • Organizer
      26th Digital Image Scientific Research Meeting in Mihara
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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