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Examination of cross-sectional and longitudinal relationships between physical examination data including physical fitness results and bone density

Research Project

Project/Area Number 17K09104
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Epidemiology and preventive medicine
Research InstitutionNiigata University

Principal Investigator

Kato Kiminori  新潟大学, 医歯学総合研究科, 特任教授 (00303165)

Co-Investigator(Kenkyū-buntansha) 曽根 博仁  新潟大学, 医歯学系, 教授 (30312846)
児玉 暁  新潟大学, 医歯学総合研究科, 特任准教授 (50638781)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords骨粗鬆症 / 耐糖能低下 / 体力測定 / 握力 / 垂直飛び / 立位前屈 / 全身反応性 / 健康診断
Outline of Final Research Achievements

Bone density data of about 90,000 people in total was analyzed. In a cross-sectional analysis with physical fitness measurements, the only factors independently associated with bone density were sex, age, weight, grip strength, standing forward bending, and whole-body reaction time. In a longitudinal analysis, the only factors independently associated with changes in bone density were gender, grip strength, and vertical jump. In addition, we are conducting a “Questionnaire survey on bone fracture events among osteoporosis screening examinees” for 17,000 people with osteoporosis screening, and we are aiming to publish the results.

Academic Significance and Societal Importance of the Research Achievements

骨粗鬆症は、特に高齢女性にとっては喫緊の課題である。骨粗鬆症によって易骨折性となっている女性が、日常的に起こりうる転倒等で骨折に至ってしまうと老後のQOLは著しく低下する。この誰にでも起こりうる骨粗鬆症を防止することは、極めて大きな医療政策の柱ともなりうる課題である。今回、得られた結果では、骨密度変化と関連している因子は握力と垂直飛びであり、これらは筋力の指標である。特に、握力はサルコペニアの定義にもなっている重要な指標であり、これらを、生活指導、運動指導の成果の指標として使うことが出来ないかと期待され、その様な意味においても本研究は将来への介入研究の基礎ともなる研究である。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (17 results)

All 2021 2020 2019 2018 2017

All Journal Article (13 results) (of which Peer Reviewed: 13 results,  Open Access: 10 results,  Acknowledgement Compliant: 1 results) Presentation (4 results)

  • [Journal Article] Physical Fitness and Dyslipidemia Among Japanese: A Cohort Study From the Niigata Wellness Study2021

    • Author(s)
      Haruki Momma, Kiminori Kato, Susumu S. Sawada, Yuko Gando, Ryoko Kawakami, Motohiko Miyachi, Ryoichi Nagatomi, Minoru Tashiro, Yasuhiro Matsubayashi, Satoru Kodama, Midori Iwanaga, Kazuya Fujihara, Hirohito Sone
    • Journal Title

      Journal of Epidemiology

      Volume: 31 Issue: 4 Pages: 287-296

    • DOI

      10.2188/jea.JE20200034

    • NAID

      130008021561

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2021-04-05
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Meta-regression Analysis of Sex- and Birth Year-Specific Prevalence of HBsAg and Anti-HCV Among Un-diagnosed Japanese: Data From the First-time Blood Donors, Periodical Health Checkup, and the Comprehensive Health Checkup With Lifestyle Education (Ningen Dock)2020

    • Author(s)
      Akita Tomoyuki、Tanaka Junko、Satake Masahiro、Lin Yingsong、Wada Takashi、Kato Kiminori、Inoue Manami
    • Journal Title

      Journal of Epidemiology

      Volume: 30 Issue: 9 Pages: 420-425

    • DOI

      10.2188/jea.JE20190055

    • NAID

      130007896964

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2020-09-05
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Combination of diabetes mellitus and lack of habitual physical activity is a risk factor for functional disability in Japanese2020

    • Author(s)
      Fujihara Kazuya、Matsubayashi Yasuhiro、Harada Yamada Mayuko、Kitazawa Masaru、Yamamoto Masahiko、Kaneko Masanori、Kodama Satoru、Yahiro Takuya、Tsutsui Ayumu、Kato Kiminori、Sone Hirohito
    • Journal Title

      BMJ Open Diabetes Research & Care

      Volume: 8 Issue: 1 Pages: e000901-e000901

    • DOI

      10.1136/bmjdrc-2019-000901

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Physical Fitness Tests and Type 2 Diabetes Among Japanese: A Longitudinal Study From the Niigata Wellness Study2019

    • Author(s)
      Momma H, Sawada SS, Kato K, Gando Y, Kawakami R, Miyachi M, Huang C, Nagatomi R, Tashiro M, Ishizawa M, Kodama S, Iwanaga M, Fujihara K, Sone H
    • Journal Title

      Journal of Epidemiology

      Volume: 29 Issue: 4 Pages: 139-146

    • DOI

      10.2188/jea.JE20170280

    • NAID

      130007624295

    • ISSN
      0917-5040, 1349-9092
    • Year and Date
      2019-04-05
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] β 2-Microglobulin and Neutrophil Gelatinase-Associated Lipocalin, Potential Novel Urine Biomarkers in Periodontitis: A Cross-Sectional Study in Japanese.2019

    • Author(s)
      Mayuka Nakajima、Michihiro Hosojima、Koichi Tabeta、Sayuri Miyauchi、Miki Yamada-Hara、Naoki Takahashi、Haruna Miyazawa、Yumi Matsuda-Matsukawa、Keisuke Sato、Noriko Sugita、Yasutaka Komatsu、Tomomi Ishikawa、Kazuhiro Akiishi、Kazuhisa Yamazaki、Kiminori Kato、Akihiko Saito、Hiromasa Yoshie
    • Journal Title

      International Journal of Dentistry

      Volume: 2019 Pages: 1-10

    • DOI

      10.1155/2019/1394678

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased serum PCSK9, a potential biomarker to screen for periodontitis, and decreased total bilirubin associated with probing depth in a Japanese community survey2018

    • Author(s)
      Tabeta K.、Hosojima M.、Nakajima M.、Miyauchi S.、Miyazawa H.、Takahashi N.、Matsuda Y.、Sugita N.、Komatsu Y.、Sato K.、Ishikawa T.、Akiishi K.、Yamazaki K.、Kato K.、Saito A.、Yoshie H.
    • Journal Title

      Journal of Periodontal Research

      Volume: 印刷中 Issue: 3 Pages: 446-456

    • DOI

      10.1111/jre.12533

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increased Levels of Cardiac Troponin I in Subjects with Extremely Low B-type Natriuretic Peptide Levels.2018

    • Author(s)
      Sugawa S, Masuda I, Kato K and Yoshimura M.
    • Journal Title

      Sci Rep.

      Volume: 8 Issue: 1 Pages: 5120-5120

    • DOI

      10.1038/s41598-018-23441-z

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Low-Dose Erythropoietin in Patients With ST-Segment Elevation Myocardial Infarction (EPO-AMI-II) ― A Randomized Controlled Clinical Trial ―2018

    • Author(s)
      Minamino, Tetsuo; Higo, Shuichiro; Araki, Ryo; Hikoso, Shungo; Nakatani, Daisaku; Suzuki, Hiroshi; Yamada, Takahisa; Okutsu, Masaaki; Yamamoto, Kouji; Fujio, Yasushi; Ishida, Yoshio; Ozawa, Takuya; Kato, Kiminori; Toba, Ken; Aizawa, Yoshifusa; Komuro, Issei
    • Journal Title

      Circulation Journal

      Volume: 82 Issue: 4 Pages: 1083-1091

    • DOI

      10.1253/circj.CJ-17-0889

    • NAID

      130006528526

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of family-oriented diabetes programs on glycemic control: A meta-analysis.2018

    • Author(s)
      Kodama S, Morikawa S, Horikawa C, Ishii D, Fujihara K, Yamamoto M, Osawa T, Kitazawa M, Yamada T, Kato K, Tanaka S and Sone H.
    • Journal Title

      Fam Pract.

      Volume: 12 Issue: 4 Pages: 111-111

    • DOI

      10.1093/fampra/cmy112

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unstable body weight and incident type 2 diabetes mellitus - A meta-analysis (in press)2017

    • Author(s)
      Kodama S, Fujihara K, Ishiguro H, Horikawa C, Ohara N, Yachi Y, Tanaka S, Shimano H, Kato K, Hanyu O, Sone H
    • Journal Title

      Journal of diabetes investigation

      Volume: - Issue: 4 Pages: 501-509

    • DOI

      10.1111/jdi.12623

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Impact of body mass index and metabolic phenotypes on coronary artery disease according to glucose tolerance status.2017

    • Author(s)
      Fujihara K, Matsubayashi Y, Yamamoto M, Osawa T, Ishizawa M, Kaneko M, Matsunaga S, Kato K, Seida H, Yamanaka N, Kodama S, Sone H
    • Journal Title

      Diabetes Metab.

      Volume: 43(6) Issue: 6 Pages: 543-546

    • DOI

      10.1016/j.diabet.2017.08.002

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Carbohydrate intake during early pregnancy is inversely associated with abnormal glucose challenge test results in Japanese pregnant women.2017

    • Author(s)
      Tajima R, Yachi Y, Tanaka Y, Kawasaki YA, Nishibata I, Hirose AS, Horikawa C, Kodama S, Iida K, Sone H.
    • Journal Title

      Diabetes Metab Res Rev.

      Volume: 33(6)

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Lower risk of progression from prediabetes to diabetes with health checkup with lifestyle education: Japan Ningen Dock study.2017

    • Author(s)
      Okada R, Tsushita K, Wakai K, Ishizaka Y, Kato K, Wada T and Watanabe K.
    • Journal Title

      Nutr Metab Cardiovasc Dis. 2017;27:

      Volume: 27 Issue: 8 Pages: 679-687

    • DOI

      10.1016/j.numecd.2017.06.004

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 骨密度に影響する身体測定値:人間ドックのデータ解析から2017

    • Author(s)
      石澤 正博, 藤原 和哉, 田代 稔, 加藤 公則, 松永 佐澄志, 山田 貴穂, 羽入 修, 曽根 博仁
    • Organizer
      第90回日本内分泌学会学術総会
    • Related Report
      2017 Research-status Report
  • [Presentation] 骨粗鬆症検診と体力測定の関係についての横断的解析 -Niigata Wellness Study-2017

    • Author(s)
      加藤公則、石澤正博、児玉 暁、藤原和哉、小林隆司、田代 稔、佐藤幸示、北川 寛、笹川 力、曽根博仁
    • Organizer
      第58回 日本人間ドック学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 骨粗鬆症検診と体力測定の関係についての縦断的解析 -Niigata Wellness Study-2017

    • Author(s)
      加藤公則、石澤正博、児玉 暁、藤原和哉、小林隆司、田代 稔、佐藤幸示、北川 寛、笹川 力、曽根博仁
    • Organizer
      第58回 日本人間ドック学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 骨粗鬆症検診と体力測定の関係-人間ドック受診者では握力と垂直飛びが骨密度と関連する-2017

    • Author(s)
      加藤公則、上村伯人
    • Organizer
      第28回日本臨床スポーツ医学会学術集会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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