Association between normal weight central obesity and life-style factors: an exploratory study using a large occupational health check-up data of Japan

• Project/Area Number: 17K09130
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Showa University
• Principal Investigator: SHIRASAWA Takako 昭和大学, 医学部, 講師 (80365759)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2018: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000); Fiscal Year 2017: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
• Keywords: 隠れ腹部肥満 / 健康診断 / BMI / 腹囲身長比 / 生活習慣 / 腹囲 / 予防医学

Outline of Final Research Achievements

The object of this study was to investigate the association between normal weight central obesity and life-style factors in Japanese middle-aged adults. The prevalence of normal weight central obesity classified using BMI and WHtR was 15.6 % in men and 30.2 % in women. Normal weight with central obesity was associated with cardiovascular disease risks such as hypertension, dyslipidemia, and diabetes, compared with normal weight without central obesity, regardless of sex. These results persisted even after adjusted for age, weight, smoking status, alcohol intakes, and physical activity. Moreover, we found that normal weight central obesity was associated with hyperuricemia in men and women, regardless of alcohol consumption.

Academic Significance and Societal Importance of the Research Achievements

職域における大規模健康診断データの解析結果から、日本の成人における隠れ腹部肥満と生活習慣との関連について性別、年代別に新知見が得られることが予想される。腹囲とBMIの組み合わせによる判定は、今後の健康診断基準の検討のための基礎資料として有意義な情報となり、労働者における隠れ腹部肥満に関連する疾病の予防に資することが期待される。

Research Products

• [Journal Article] Cross-sectional study of associations between normal body weight with central obesity and hyperuricemia in Japan (2020)
  • Author(s): Shirasawa Takako、Ochiai Hirotaka、Yoshimoto Takahiko、Nagahama Satsue、Watanabe Akihiro、Yoshida Reika、Kokaze Akatsuki
  • Journal Title: BMC Endocrine Disorders Volume: 20 Issue: 1 Pages: 2-2
  • DOI: 10.1186/s12902-019-0481-1
  • Peer Reviewed / Open Access
• [Journal Article] Associations between normal weight central obesity and cardiovascular disease risk factors in Japanese middle-aged adults: a cross-sectional study (2019)
  • Author(s): Shirasawa Takako、Ochiai Hirotaka、Yoshimoto Takahiko、Nagahama Satsue、Kobayashi Mariko、Ohtsu Iichiro、Sunaga Yuma、Kokaze Akatsuki
  • Journal Title: Journal of Health, Population and Nutrition Volume: 38 Issue: 1 Pages: 46-46
  • DOI: 10.1186/s41043-019-0201-5
  • Peer Reviewed / Open Access
• [Presentation] 中高年女性における夜遅い食事及び夜食と肥満・腹部肥満との関連（ZRF study 第18報）. (2019)
  • Author(s): 白澤貴子、落合裕隆、吉本隆彦、長濱さつ絵、星野祐美、小風暁.
  • Organizer: 第78回日本公衆衛生学会総会
• [Presentation] 飲酒習慣別、肥満・腹部肥満の組合せと高尿酸血症の関連（ZRF study 第14報） (2018)
  • Author(s): 白澤貴子、落合裕隆、吉本隆彦、長濱さつ絵、小林真理子、箕浦明、星野祐美、小風暁
  • Organizer: 第77回日本公衆衛生学会総会