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Research on incentive for reduction the number of drugs in elderly with polypharmacy

Research Project

Project/Area Number 17K09231
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical and hospital managemen
Research InstitutionGifu University

Principal Investigator

Yuichi Hayashi  岐阜大学, 医学部附属病院, 講師 (00392366)

Co-Investigator(Kenkyū-buntansha) 鈴木 昭夫  岐阜大学, 医学部附属病院, 准教授 (80775148)
Project Period (FY) 2017-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsポリファーマシー / 高齢者 / 多剤処方 / インセンティブ / 電子カルテ / インセンティブ付与制度 / 医療保険 / 保険制度 / 電子カルテシステム
Outline of Final Research Achievements

Polypharmacy is a major problem for elderly patients in developed countries. Because adverse drug-related problems are increasing in the patients who received 5 or more drugs. Therefore, reducing the number of drugs is required. In Japan, public health insurance system decided the incentive for reduction the number of drugs for patients receiving 6 or more drugs in case of reduction for 2 or more drugs. We investigated the efficacy of this incentive in public health insurance system. There is an effectiveness for especially in diabetic elderly patients with polypharmacy.

Academic Significance and Societal Importance of the Research Achievements

高齢者のポリファーマシーの是正に対しては、一部の多剤処方高齢者では、保険制度上のインセンティブ付与制度は、有用に働いている。高齢者のポリファーマシーの是正の1つの方法として、保険制度上のインセンティブ付与制度が有益であると考えられ、今後も増える高齢者の医療対策の1つとして存続すべき意義のある制度と考えた。

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (26 results)

All 2022 2021 2020 2019 2018 2017 Other

All Journal Article (15 results) (of which Peer Reviewed: 9 results,  Open Access: 1 results) Presentation (10 results) (of which Int'l Joint Research: 2 results,  Invited: 5 results) Remarks (1 results)

  • [Journal Article] Albumin-bilirubin score for predicting neuropsychiatric symptoms in patients receiving ifosfamide-based chemotherapy.2021

    • Author(s)
      Shimizu S, Hayashi Y, Nishida S, Fuji H, Nakamura M, Yoshikura N, Nagata A, Kitagawa J, Kanemura N, Mizutani K, Kobayashi R, Hayashi H, Ishihata T, Shimohata T, Sugiyama T, Suzuki A.
    • Journal Title

      J Clin Pharm Ther

      Volume: 46 Pages: 794-799

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] irAEの重症例と診療上の注意点2021

    • Author(s)
      林 祐一
    • Journal Title

      薬事日報

      Volume: 12401 Pages: 4-4

    • Related Report
      2020 Research-status Report
  • [Journal Article] 高齢者のポリファーマシーに関する問題―病棟医師の立場から―2020

    • Author(s)
      林 祐一
    • Journal Title

      日本内科学雑誌

      Volume: 109 Pages: 2208-2210

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] 高齢者のポリファーマシーに関する問題 ―病棟医師の立場から―2020

    • Author(s)
      林 祐一
    • Journal Title

      日本内科学雑誌

      Volume: 109

    • Related Report
      2019 Research-status Report
  • [Journal Article] Adverse event profiles of ifosfamide-induced encephalopathy analyzed using the Food and Drug Administration Adverse Event Reporting System and the Japanese Adverse Drug Event Report databases2019

    • Author(s)
      Shimada Kazuyo, Hasegawa Shiori, Nakao Satoshi, Mukai Ririka, Matsumoto Kiyoka, Tanaka Mizuki, Uranishi Hiroaki, Masuta Mayuko, Nishida Shohei, Shimizu Shinya, Hayashi Yuichi, Suzuki Akio, Nakamura Mitsuhiro
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 16 Issue: 5 Pages: 1295-1303

    • DOI

      10.1007/s00280-019-03949-5

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] 高齢者医療ハンドブック ポリファーマシー2018

    • Author(s)
      林 祐一
    • Journal Title

      内科

      Volume: 121 Pages: 960-963

    • Related Report
      2018 Research-status Report 2017 Research-status Report
  • [Journal Article] 専門領域別にみた処方適正化のアプローチ 神経筋疾患2018

    • Author(s)
      林 祐一、鈴木昭夫
    • Journal Title

      月刊薬事

      Volume: 60 Pages: 2054-2058

    • Related Report
      2018 Research-status Report
  • [Journal Article] rug-induced pressure ulcers in a middle-aged patient with early stage of Parkinson’s disease2018

    • Author(s)
      Hayashi Y, Shibata H, Kudo T, Nishida S, Ishikawa R, Suzuki A, Kimura A, Inuzuka T.
    • Journal Title

      Internal Med

      Volume: 57 Pages: 1483-1486

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 専門領域別にみた処方適正化のアプローチ‐神経筋疾患2018

    • Author(s)
      林 祐一、鈴木昭夫
    • Journal Title

      月刊薬事

      Volume: in press

    • Related Report
      2017 Research-status Report
  • [Journal Article] Relationship between number of drugs and duration of hospital stay in elderly patients with neuromuscular disease.2018

    • Author(s)
      Nishida S, Hayashi Y, Suzuki A, Kobayashi R, Inuzuka T, Itoh Y.
    • Journal Title

      Geriatr Gerontol Int

      Volume: in press

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Drug-induced pressure ulcers in a middle-aged patient with early stage of Parkinson’s disease2018

    • Author(s)
      Hayashi Y, Shibata H, Kudo T, Nishida S, Ishikawa R, Suzuki A, Kimura A, Inuzuka T
    • Journal Title

      Intern Med

      Volume: in press

    • NAID

      130006734434

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] ポリファーマシー2017

    • Author(s)
      林 祐一
    • Journal Title

      日本食品科学工学雑誌

      Volume: 64 Pages: 517-518

    • NAID

      130006183023

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 高齢者のポリファーマシーの是正と電子カルテシステムの役割2017

    • Author(s)
      林 祐一、犬塚 貴
    • Journal Title

      医学のあゆみ

      Volume: 252 Pages: 726-727

    • Related Report
      2017 Research-status Report
  • [Journal Article] Reduction in the numbers of drugs administered to elderly in-patients with polypharmacy by a multidisciplinary review of medication using electronic medical records.2017

    • Author(s)
      Hayashi Y, Godai A, Yamada M, Yoshikura N, Harada N, Koumura A, Kimura A, Okayasu S, Mastuno Y, Kinosada Y, Itoh Y, Inuzuka T
    • Journal Title

      Geriatr Gerontol Int

      Volume: 17 Pages: 653-658

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] ウレアーゼ産生菌の尿路感染から高アンモニア血症を来した1例-薬剤性の尿閉が一因となり、意識障害を来したパーキンソン病症例2017

    • Author(s)
      安西将大、香村彰宏、林 祐一、西田承平、犬塚 貴
    • Journal Title

      日本老年医学会雑誌

      Volume: 54 Pages: 560-566

    • NAID

      130006247152

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 糖尿病代謝内科病棟におけるポリファーマシー対策の評価2022

    • Author(s)
      山田翔也、西田承平、林祐一、浅井奈央、山田未知、藤井宏典、鈴木昭夫
    • Organizer
      日本医療薬学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 医師の視点で考える薬剤誘発性褥瘡.2021

    • Author(s)
      林 祐一
    • Organizer
      第3回皮膚褥瘡外用薬学会学術集会
    • Related Report
      2020 Research-status Report
    • Invited
  • [Presentation] 高齢者のポリファーマシーに関する問題 ―病棟医師の立場から―2019

    • Author(s)
      林 祐一
    • Organizer
      第28回日本内科学会東海支部教育セミナー
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] irAEに関する内科的理解と重篤な症例に対する診断と対応2019

    • Author(s)
      林 祐一、飯原大稔、鈴木昭夫
    • Organizer
      第29回日本医療薬学会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 神経内科領域におけるポリファーマシー対策2018

    • Author(s)
      林 祐一
    • Organizer
      第28回日本医療薬学会年会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 神経内科領域におけるポリファーマシー対策2018

    • Author(s)
      林 祐一
    • Organizer
      日本医療薬学会
    • Related Report
      2017 Research-status Report
  • [Presentation] ポリファーマシーとどう向き合うか.入院を契機とした高齢者のポリファーマシー是正と電子カルテシステムの役割.2017

    • Author(s)
      林 祐一
    • Organizer
      第59回日本老年医学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Necessity of a drug-related item for a geriatric inpatient fall assessment tool.2017

    • Author(s)
      Hayashi Y, Nishida S, Tamai S, Suzuki A, Kimura A, Itoh Y, Inuzuka T
    • Organizer
      The 77th FIP World Congress of Pharmacy and Pharmaceutical Sciences
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] A search for drugs with increased risk for worse clinical outcomes in elderly patients receiving multi-drug therapy.2017

    • Author(s)
      Nishida S, Suzuki A, Hayashi Y, Kobayashi R, Inuzuka T, Itoh Y
    • Organizer
      The 77th FIP World Congress of Pharmacy and Pharmaceutical Sciences
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Polypharmacy in elderly patients and a role of electronic medical record system.2017

    • Author(s)
      Hayashi Y, Inuzuka T.
    • Organizer
      The 2nd Geriatric Innovation forum
    • Related Report
      2017 Research-status Report
    • Invited
  • [Remarks] ポリファーマシー

    • URL

      http://www.med.gifu-u.ac.jp/neurology/research/polypharmacy.html

    • Related Report
      2019 Research-status Report 2018 Research-status Report

URL: 

Published: 2017-04-28   Modified: 2023-01-30  

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