Proposal of exercise therapy for heart disease patients using wearable activity and heart rate monitor and investigation of prognosis
| Project/Area Number |
17K09533
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Fujita Health University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
吉岡 公一郎 東海大学, 医学部, 教授 (30246087)
清野 健 大阪大学, 基礎工学研究科, 教授 (40434071)
原田 将英 藤田医科大学, 医学部, 准教授 (70514800)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 運動耐容能 / 予後 / 循環器疾患 / フレイル / 心疾患 / サルコペニア / 心拍 / 体動 / 加速度 / ウェアラブル / 身体的フレイル / 心拍応答特性 / リハビリテーション |
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| Outline of Final Research Achievements |
In healthy people, the heart rate rapidly increases in response to physical activity, but in heart disease patients, the ability to control heart rate with exercise decreases due to autonomic nervous dysfunction and frailty. Although this "chronotropic response" is associated with QOL and prognosis, a simple measurement method has not been developed. In this study, after performing frailty questionnaire for heart disease patients, wearable activity / heart rate monitor was attached to the chest, and the ratio of acceleration deviation (exercise / work intensity) to heart rate was defined as the chronotropic response. Analysis showed that the heart disease patients had lower chronotropic response than those of healthy subjects, and a negative correlation with the frailty score was observed. In conclusion, our data suggested that the chronotropic response could be easily obtained in daily life and that it could be a new flail evaluation method.
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| Academic Significance and Societal Importance of the Research Achievements |
高齢化に伴い心臓病患者が増加しているが、これは社会的にも医療経済的にも大きな問題である。運動療法は心臓病の予防と病態の進行抑制に有効であるが、個々の心拍応答特性に見合った運動処方を行うには高度な検査が必要である。本研究ではウェアラブルモニターを用いて、日常生活下の心拍応答特性算出アルゴリズムを開発した。心臓病患者の心拍応答特性は約7000人の健常人より求められた基準範囲より低下しており、さらに、心拍応答特性はフレイル評価値と負の相関が認められた。本研究によりウェアラブルモニターを貼付することでフレイル評価と心拍応答特性の算出ができ、これに基づく運動処方が行える可能性がある。
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Report
(4 results)
Research Products
(30 results)
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[Journal Article] Clinical experience of idarucizumab use in cases of cardiac tamponade under uninterrupted anticoagulation of dabigatran during catheter ablation of atrial fibrillation.2019
Author(s)
Okishige K, amauchi Y, Hanaki Y, Inoue K, Tanaka N, Yamaji H, Murakami T, Manita M, Tabata K, Ooie T, Tatsukawa Y, Sakai H, Yamaki M, Murakami M, Takada T, Osaka Y, Ono Y, Handa K, Sugiyama K, Yoshizawa T, Fukaya H, Tashiro H, Takase S, Harada M, Watanabe E, Yamane T, Yamashita S, Aonuma K,
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Journal Title
J Thromb Thrombolysis
Volume: 47
Issue: 4
Pages: 487-494
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Prognostic Value of Combination of Plasma D-Dimer Concentration and Estimated Glomerular Filtration Rate in Predicting Long-Term Mortality of Patients With Stable Coronary Artery Disease2017
Author(s)
Naruse H, Ishii J, Takahashi H, Kitagawa F, Okuyama R, Kawai H, Muramatsu T, Harada M, Yamada A, Motoyama S, Matsui S, Hayashi M, Sarai M, Watanabe E, Izawa H, Ozaki Y.
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Journal Title
Circulation Journal
Volume: 81
Issue: 10
Pages: 1506-1513
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Open Access
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[Book] はじまりは心房細動2017
Author(s)
奥山 裕司、渡邉 英一
Total Pages
151
Publisher
ライフメディコム
ISBN
9784898132845
Related Report
