• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The identification of the cause site of pediatric OSAS by the three-dimensional sleep breath model built using new technology

Research Project

Project/Area Number 17K11965
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthodontics/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

Iwasaki Tomonori  鹿児島大学, 医歯学域歯学系, 准教授 (10264433)

Co-Investigator(Kenkyū-buntansha) 山崎 要一  鹿児島大学, 医歯学域歯学系, 教授 (30200645)
原田 みずえ  鹿児島大学, 医歯学域医学系, 助教 (20585103)
原 浩貴  川崎医科大学, 医学部, 教授 (90274167)
大井 一浩  金沢大学, 附属病院, 講師 (90451450)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords小児OSA / 原因部位 / 流体解析 / 3次元モデル / OSA / 小児 / 小児OSAS / 睡眠呼吸モデル / 小児OSAS
Outline of Final Research Achievements

The good treatment result is not obtained without the treatment that accepted cause site being chosen because there is not the precise identification method of the obstruction site in pediatric obstructive sleep apnoea (OSA) resulting from upper airway obstruction.As for this study, a resistance level of the ① nasal airway fluid simulation established the construction method of the upper airway model that the living body who was similar to a resistance level of the nasal airway ventilation degree testing was near to establish a specific method of the cause site of pediatric OSA.(2) Established the manufacture method of the pharyngeal airway transformation predictive model at apnea sleeping from a pharyngeal airway model at awakening, and suggested a specific method of the cause site.

Academic Significance and Societal Importance of the Research Achievements

OSAの治療には通気障害部位に応じた治療方法の選択が重要になってくるものの、上気道の形態が複雑なため、正確な原因部位の特定は困難だった。そのため、原因部位に応じた適切な治療方法が選択されておらず、治療の第一選択となるアデノイド切除・口蓋扁桃摘出術の治癒率は60%前後と低く精度の高い通気障害部位の特定法の開発が待ち望まれていた。しかし、本研究で原因部位の特定だけでなく、閉塞部位との鑑別を可能にした。このことは本来原因部位でないものの、閉塞を認めたため切除対象となっていた部位を明らかにし、真の原因部位のみを検出することで、最小限の侵襲で最大限の治療成績の獲得が期待できる画期的な方法を開発した。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (21 results)

All 2019 2018 2017 Other

All Int'l Joint Research (4 results) Journal Article (9 results) (of which Peer Reviewed: 9 results,  Open Access: 5 results) Presentation (7 results) (of which Int'l Joint Research: 1 results,  Invited: 4 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Int'l Joint Research] シドニー大学(オーストラリア)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] スタンフォード大学/カリフォルニア大学ロサンゼルス校/カリフォルニア大学サンフランシスコ校(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Stanford Univ,/UCSF/UCLA(米国)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] Stanford University/UCSF(米国)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Evaluation of the effect of oral-appliance treatment on upper-airway ventilation conditions in obstructive sleep apnea using computational fluid dynamics2019

    • Author(s)
      Suga H, Iwasaki T, Mishima K, Nakano H, Ueyama Y, Yamasaki Y.
    • Journal Title

      Cranio

      Volume: 印刷中 Issue: 3 Pages: 1-9

    • DOI

      10.1080/08869634.2019.1596554

    • NAID

      120006980535

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Rapid maxillary expansion effects of nasal airway in children with cleft lip and palate using computational fluid dynamics2019

    • Author(s)
      Iwasaki Tomonori、Yanagisawa‐Minami Ayaka、Suga Hokuto、Shirazawa Yoshito、Tsujii Toshiya、Yamamoto Yuushi、Ban Yuusuke、Sato‐Hashiguchi Makiko、Sato Hideo、Kanomi Ryuzo、Yamasaki Youichi
    • Journal Title

      Orthodontics & Craniofacial Research

      Volume: - Issue: 3 Pages: 201-207

    • DOI

      10.1111/ocr.12311

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Upper airway in children with unilateral cleft lip and palate evaluated with computational fluid dynamics2019

    • Author(s)
      Iwasaki Tomonori、Suga Hokuto、Minami-Yanagisawa Ayaka、Hashiguchi-Sato Makiko、Sato Hideo、Yamamoto Yuushi、Shirazawa Yoshito、Tsujii Toshiya、Kanomi Ryuzo、Yamasaki Youichi
    • Journal Title

      American Journal of Orthodontics and Dentofacial Orthopedics

      Volume: 156 Issue: 2 Pages: 257-265

    • DOI

      10.1016/j.ajodo.2018.09.013

    • NAID

      120006979185

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Upper airway evaluation of children with unilateral cleft lip and palate using computational fluid dynamics2019

    • Author(s)
      Tomonori Iwasaki, Hokuto Suga, Ayaka Minami-Yanagisawa, Makiko Hashiguchi-Sato, Hideo sato, Yuushi yamamoto, Yoshito Shirazawa, Toshiya Tsujii, Ryuzo Kanomi, Youichi Yamasaki
    • Journal Title

      American Journal of Orthodontics & Dentofacial Orthopedics

      Volume: ー

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationships among tongue volume, hyoid position, airway volume and maxillofacial form in paediatric patients with Class-I, Class-II and Class-III malocclusions2018

    • Author(s)
      Iwasaki Tomonori、Suga Hokuto、Yanagisawa-Minami Ayaka、Sato Hideo、Sato-Hashiguchi Makiko、Shirazawa Yoshito、Tsujii Toshiya、Yamamoto Yuushi、Kanomi Ryuzo、Yamasaki Youichi
    • Journal Title

      Orthodontics & Craniofacial Research

      Volume: 22 Issue: 1 Pages: 9-15

    • DOI

      10.1111/ocr.12251

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaluation of the pharyngeal airway using computational fluid dynamics in patients with acromegaly2018

    • Author(s)
      Mukaihara Keika、Hasegawa-Moriyama Maiko、Iwasaki Tomonori、Yamasaki Youichi、Kanmura Yuichi
    • Journal Title

      Laryngoscope Investigative Otolaryngology

      Volume: 1 Issue: 2 Pages: 1-6

    • DOI

      10.1002/lio2.151

    • NAID

      120006980525

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Relationships between nasal resistance, adenoids, tonsils, and tongue posture and maxillofacial form in Class II and Class III children.2017

    • Author(s)
      Iwasaki T, Sato H, Suga H, Takemoto Y, Inada E, Saito I, Kakuno E, Kanomi R, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics & Dentofacial Orthopedics.

      Volume: 151 Issue: 5 Pages: 929-40

    • DOI

      10.1016/j.ajodo.2016.10.027

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of Herbst appliance on pharyngeal airway ventilation conditions evaluated using computational fluid dynamics.2017

    • Author(s)
      Iwasaki T, Sato H, Suga H, Minami A, Yamamoto Y, Takemoto Y, Inada E, Saitoh I, Kakuno E, Kanomi R, Yamasaki Y
    • Journal Title

      The Angle Orthodontist.

      Volume: 87 Issue: 3 Pages: 397-403

    • DOI

      10.2319/080616-603.1

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of pharyngeal airway respiration pressure on Class II mandibular retrusion in children: a computational fluid dynamics study of inspiration and expiration2017

    • Author(s)
      Iwasaki T, Sato H, Suga H, Takemoto Y, Inada E, Saito I, Kakuno E, Kanomi R, Yamasaki Y
    • Journal Title

      Orthodontics & Craniofacial Research

      Volume: 20 Issue: 2 Pages: 95-101

    • DOI

      10.1111/ocr.12145

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 上気道流体シミュレーションを用いた口唇口蓋裂児の鼻腔の上顎急速拡大効果2019

    • Author(s)
      岩崎 智憲, 菅 北斗, 柳澤 彩佳, 白澤 良執, 辻井 利弥, 橋口 真紀子, 武元 嘉彦, 嘉ノ海 龍三, 山崎 要一
    • Organizer
      日本小児歯科学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] OSA数値流体力学解析up-todate 上気道流体シミュレーションによるOSA原因部位の特定と閉塞部位との鑑別診断2019

    • Author(s)
      岩﨑智憲
    • Organizer
      日本睡眠学会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 上気道流体シミュレーションを用いた小児OSASの原因部位特定方法の検討2019

    • Author(s)
      柳澤 彩佳, 岩崎 智憲, 杉山 剛, 佐藤 秀夫, 菅 北斗, 山本 祐士, 橋口 真紀子, 杉田 完爾, 山崎 要一
    • Organizer
      日本睡眠学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 上気道流体力学上気道流体力学解析を用いた口腔内装置の治療効果と通気障害部位に基づく適応の判定解析を用いた口腔内装置の治療効果と通気障害部位に基づく適応の判定2019

    • Author(s)
      菅 北斗, 岩崎 智憲, 三島 克章, 中野 旬之, 上山 吉哉, 山崎 要一
    • Organizer
      日本睡眠学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Indication of the Dental Treatment for Pediatric OSAS using Computer Fluid Dynamics2018

    • Author(s)
      Tomonri Iwasaki
    • Organizer
      21st General Assembly, 41th Annual Scientific Meeting and Dental Exhibition
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 上気道流体シミュレーションを用いた 小児OSAの原因部位特定について2018

    • Author(s)
      岩崎智憲
    • Organizer
      日本睡眠歯科学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 流体解析を用いた小児 OSAS の原因部位特定2018

    • Author(s)
      岩崎智憲
    • Organizer
      成育歯科医療研究会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Patent(Industrial Property Rights)] AIRWAY VENTILATION STATE CALIBRATION SYSTEM AND SYSTEM FOR PREDICTING AIRWAY DEFORMATION DURING SLEEP2019

    • Inventor(s)
      岩崎智憲
    • Industrial Property Rights Holder
      岩崎智憲
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Related Report
      2019 Annual Research Report
    • Overseas

URL: 

Published: 2017-04-28   Modified: 2022-02-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi