| Project/Area Number |
17K12017
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Kyushu Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
安細 敏弘 九州歯科大学, 歯学部, 教授 (80244789)
岩崎 正則 九州歯科大学, 歯学部, 准教授 (80584614)
中道 郁夫 九州歯科大学, 歯学部, 准教授 (60419570)
藤澤 律子 九州歯科大学, 歯学部, 助教 (50419587)
井手 均 九州歯科大学, 歯学部, 特別研修員 (10795537)
園木 一男 九州歯科大学, 歯学部, 教授 (50316155)
粟野 秀慈 九州歯科大学, 歯学部, 教授 (20301442)
秋房 住郎 九州歯科大学, 歯学部, 教授 (40295861)
邵 仁浩 九州歯科大学, 歯学部, 教授 (10285463)
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| Project Period (FY) |
2017-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 高齢者 / コホート研究 / 嚥下障害 / 反復唾液嚥下テスト / 肺炎 / 呼吸器感染症 / 死亡 |
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| Outline of Final Research Achievements |
In 1998，827 80-year-01d residents of Fukuoka Prefecture participated the dental and medical examination, which included the repetitive saliva swallowing test (RSST). The RSST is a safe and simple screening method for the swallowing function and evaluates how many times people can swallow in 30 seconds. Less than 3 cycles is considered as abnormal. We followed up 822, who completed the RSST, and investigated the association between dysphagia and mortality rate from pneumonia. For 12 years 504 died. Eighty-one died of pneumonia. Kaplan-Meier method showed the mortality rate from pneumonia was significantly higher in the subjects with dysphagia compared to the subjects without dysphagia (p<0.05)．In Cox proportional hazard model，dysphagia is a significant and independent risk factor for death of respiratory disease（hazard ratio 1.6）. The mortality rate from pneumonia was significantly higher in the subjects with dysphagia evaluated by RSST.
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| Academic Significance and Societal Importance of the Research Achievements |
嚥下機能検査としては、様々あるが、侵襲的なものが多い。非侵襲的な嚥下機能スクリーニング検査として、反復唾液嚥下テスト（RSST）がある（Kubota T et al, General Rehabilitaiton, 1982）。反復唾液嚥下テストが、肺炎の発症あるいは死亡を予測するかの検討が行われているが、多くは脳卒中患者や施設入所者での検討である。
本研究は、福岡県8020追跡コホートを用いて、反復唾液嚥下テストで評価した嚥下障害と死亡との関連を検討し、肺炎の死亡の予測因子としての反復唾液嚥下テストの意義を示した。
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