| Project/Area Number |
17K12289
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Lifelong developmental nursing
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| Research Institution | Tottori University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
鈴木 康江 鳥取大学, 医学部, 教授 (10346348)
原田 崇 鳥取大学, 医学部, 講師 (00437550)
大谷 多賀子 鳥取大学, 医学部, 助教 (20710031)
大島 麻美 鳥取大学, 医学部, 助教 (90758161)
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| Project Period (FY) |
2017-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2020: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | 腟内細菌叢 / 食物摂取 / プロバイオティクス / ビタミンD / 妊婦 / 食習慣 / 妊婦の生活習慣 / 早産予防 / 妊娠期の生活習慣 / 生活習慣 / 周産期看護 |
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| Outline of Final Research Achievements |
The study was planned to investigate the association between lifestyle habits during pregnancy and vaginal and intestinal microbiota and pregnancy outcomes, followed by the development and evaluation of a health education program to promote lifestyle habits that can prevent preterm delivery. However, the study was interrupted due to the COVID-19 epidemic. This made it difficult to accomplish the original objectives within the research period. Therefore, we decided to accomplish some of the research objectives. A literature review was conducted on lifestyle habits that affect the vaginal microflora of pregnant women. The literature review focused specifically on "food intake and vaginal microflora during pregnancy". The results suggested that certain probiotics and vitamin D intake were suggested as foods that have a positive effect on the vaginal microflora.
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| Academic Significance and Societal Importance of the Research Achievements |
妊婦の細菌性腟症は早産リスクとなる。妊婦の腟内細菌叢を整えることが早産予防につながると考えられる。我々の先行研究では、妊娠初期の腟内細菌叢と食習慣（大豆発酵食品、キノコ類等）に関連があった。また、妊婦の腟内細菌叢は腸内細菌叢と関連することも示唆されている。食生活は腸内細菌叢にも影響する。本研究は、腟内細菌叢の正常化に特定のプロバイオティクスやビタミンDが寄与する可能性があることを明らかにした。この結果は、妊婦の食生活に関する健康教育に活用できる。
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