Development of neurofeedback training to promote motor function recovery of paralyzed upper limbs in stroke patients

• Project/Area Number: 17K13078
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Kyoto Tachibana University
• Principal Investigator: Nakano Hideki 京都橘大学, 健康科学部, 准教授 (60605559)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: 脳卒中 / リハビリテーション / 理学療法 / ニューロフィードバック / 運動イメージ / 脳波 / 運動制御 / 運動学習 / ニューロリハビリテーション / 聴覚 / 神経科学

Outline of Final Research Achievements

This study aimed to investigate the effect of auditory neurofeedback training with motor imagery on upper extremity function and motor imagery ability in a stroke patient. The participant performed auditory neurofeedback training with motor imagery in addition to standard rehabilitation during the intervention period. The scores of upper extremity function and motor imagery ability improved after the intervention. This study suggests that auditory neurofeedback training with motor imagery contributes to improving upper extremity function and motor imagery ability in stroke patients.

Academic Significance and Societal Importance of the Research Achievements

本研究により，運動イメージを用いた聴覚ニューロフィードバックトレーニングは，脳卒中患者の麻痺側上肢機能と運動イメージ能力の改善に貢献することが示唆された．本研究成果は，脳卒中後のリハビリテーション，特に随意運動が困難な脳卒中患者の麻痺側上肢機能ならびに運動イメージ能力を改善させるツールとして広く臨床応用できると考える．

Research Products

• [Journal Article] Treatment of Medial Medullary Infarction Using a Novel iNems Training: A Case Report and Literature Review (2019)
  • Author(s): Kodama T, Katayama O, Nakano H, Ueda T, Murata S
  • Journal Title: Clinical EEG and Neuroscience Volume: 印刷中 Issue: 6 Pages: 429-435
  • DOI: 10.1177/1550059419840246
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effect of Auditory Neurofeedback Training on Upper Extremity Function and Motor Imagery Ability in a Stroke Patient: A Single Case Study (2018)
  • Author(s): Nakano Hideki、Kodama Takayuki、Murata Shin、Nakamoto Takayuki、Fujihara Takaaki、Ito Yoshiharu
  • Journal Title: International Journal of Clinical Research & Trials Volume: 3 Issue: 2 Pages: 1-5
  • DOI: 10.15344/2456-8007/2018/126
  • Peer Reviewed / Open Access
• [Journal Article] Reliability and Validity of the Japanese Version of the Kinesthetic and Visual Imagery Questionnaire (KVIQ) (2018)
  • Author(s): Nakano H, Kodama T, Ukai K, Kawahara S, Horikawa S, Murata S
  • Journal Title: Brain Sciences Volume: 8(5) Issue: 5 Pages: 1-7
  • DOI: 10.3390/brainsci8050079
  • Peer Reviewed / Open Access
• [Journal Article] The association between brain activity and motor imagery during motor illusion induction by vibratory stimulation (2017)
  • Author(s): Kodama T, Nakano H, Katayama O, Murata S
  • Journal Title: Restorative Neurology and Neuroscience Volume: 35(6) Issue: 6 Pages: 683-692
  • DOI: 10.3233/rnn-170771
  • Peer Reviewed / Open Access
• [Book] Rehabilitation Strategies and Key Related Mechanisms Involved in Stroke Recovery. New Insight into Cerebrovascular Diseases: An Updated Comprehensive Review (2020)
  • Author(s): Nakano H
  • Publisher: IntechOpen
• [Book] Strategies and Underlying Brain Mechanisms of Motor Learning. Motor Learning: A Review and Directions for Research (2017)
  • Author(s): Nakano H, Kodama T
  • Total Pages: 128
  • Publisher: Nova Science Publishers
  • ISBN: 9781536125047
• [Book] Understanding Neural Mechanisms of Action Observation for Human Motor Skill Acquisition. Electroencephalography (2017)
  • Author(s): Nakano H, Kodama T
  • Publisher: InTech
  • ISBN: 9789535136385
• [Book] Motor Imagery and Action Observation as Effective Tools for Physical Therapy. Neurological Physical Therapy (2017)
  • Author(s): Nakano H, Kodama T
  • Publisher: InTech
  • ISBN: 9789535131144
• [Book] Neuroscience-Based Rehabilitation for Stroke Patients. Neurological Physical Therapy (2017)
  • Author(s): Kodama T, Nakano H
  • Publisher: InTech
  • ISBN: 9789535131144
• [Remarks] 京都橘大学ニューロリハビリテーション研究室
  • URL: https://www.nakano-neuroreha.com/