Development of an effective arteriosclerosis prevention exercise programme based on the synchronization between cardiac and locomotor rhythms

• Project/Area Number: 17K13226
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science
• Research Institution: International University of Health and Welfare
• Principal Investigator: Takeuchi Shinta 国際医療福祉大学, 成田保健医療学部, 講師 (10599898)
• Project Period (FY): 2017-04-01 – 2022-03-31
• Project Status: Completed (Fiscal Year 2021)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2017: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 心拍数 / 歩行 / 酸素摂取量 / 同期現象 / 虚血性心疾患 / 運動療法 / 動脈硬化 / 心拍リズム / 運動リズム

Outline of Final Research Achievements

The present study investigated the mechanisms and characteristics of the occurrence of Cardiac-Locomotor Synchronisation (CLS) with the aim of investigating the adaptation and safety of exercise programmes based on the phenomenon of CLS. The results showed that CLS was more likely to occur in young healthy subjects with low physical fitness and those who had no exercise habits. It was also found to be more likely to occur in the elderly than in the young and in patients with ischaemic heart disease compared with healthy subjects of the same age. These results suggest that the occurrence of CLS is related to the exercise tolerance of the subjects, as well as to respiratory sinus arrhythmias and reduced arterial baroreflex sensitivity.

Academic Significance and Societal Importance of the Research Achievements

本研究では心拍－運動リズム間の同期現象（Cardiac-Locomotor Synchronization：CLS）に関する発生機序や発生特性の解明に取り組み、低体力者や高齢者、循環器疾患患者などの運動継続が困難となりやすい対象者ではCLSが発生しやすい可能性を示した。CLSが発生している際には骨格筋への血液供給が最適化されることや、心臓仕事量が軽減されることが報告されている。そのため、本研究で明らかになったCLSの発生特性は、CLSが運動の維持をサポートするための生体の反応であることを裏付けると考えられ、医療や健康増進分野での研究へと繋がる発展性を示すことに貢献したと考えられる。

Research Products

• [Journal Article] Validity of anaerobic threshold measured in resistance exercise (2022)
  • Author(s): Masuda Takayuki、Takeuchi Shinta、Kubo Yusuke、Nishida Yusuke
  • Journal Title: Journal of Physical Therapy Science Volume: 34 Issue: 3 Pages: 199-203
  • DOI: 10.1589/jpts.34.199
  • ISSN: 0915-5287, 2187-5626
  • Peer Reviewed / Open Access
• [Journal Article] Influences of exercise capacity on cardiolocomotor coupling during walking in young people. (2018)
  • Author(s): Shinta Takeuchi, Yurina Yokoyama, Yusuke Nishida
  • Journal Title: International Journal of Sport, Exercise and Health Research Volume: 印刷中 Issue: 1 Pages: 83-87
  • DOI: 10.31254/sportmed.2102
  • Peer Reviewed / Open Access
• [Presentation] 心拍-運動リズム間における同期現象の理学療法応用 (2020)
  • Author(s): 竹内真太
  • Organizer: 第25回日本基礎理学療法学会学術大会
• [Presentation] 虚血性心疾患発症に伴う循環器の機能低下は心拍－運動リズム間における同調現象の発生を強める (2017)
  • Author(s): 竹内真太、西田裕介
  • Organizer: 第52回日本理学療法学術大会