Research Project
Grant-in-Aid for Young Scientists (B)
Microneedle arrays with porous structures were applied to wearable sensors of interstitial fluid of skin with various modalities. A fluorescent sensor bearing a boronic acid moiety was integrated into micropores of the microneedles to demonstrate potential for the measurement of glucose concentration. Electroless plating on the micropore surface allowed for the electrochemical sensing of glucose by glucose oxidase.
皮膚組織液中の成分を精密・高感度に定量することで，生体の状態を簡便かつ正確に知ることができるようになる。本研究は，そのための基盤技術の探索を行ったものである。大きな比表面積を有する多孔質マイクロニードル電極の作製に成功し，経皮グルコースセンサの基本設計に目処を付けた。グルコース以外の生体成分の測定にも応用可能性がある。
All 2019 2018 2017 Other
All Journal Article (2 results) (of which Peer Reviewed: 2 results, Open Access: 1 results) Presentation (12 results) (of which Int'l Joint Research: 2 results, Invited: 1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)
Analyst
Volume: 143 Issue: 22 Pages: 5545-5551
10.1039/c8an00979a
RSC Advances
Volume: 8 Issue: 29 Pages: 15985-15990
10.1039/c8ra02655f
http://hirokai.github.io/about/index.ja.html
