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Elucidation of the molecular basis of immune response in plants

Research Project

Project/Area Number 17K15141
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Plant molecular biology/Plant physiology
Research InstitutionNara Institute of Science and Technology

Principal Investigator

TAKAHASHI Naoki  奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 (40553623)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords病原菌 / シロイヌナズナ / 植物免疫 / シグナル伝達 / DNA損傷 / 免疫 / 植物 / 防御応答 / 発現制御
Outline of Final Research Achievements

Understanding the mechanism of defense response against pathogen challenge not only leads to elucidation of the molecular basis of immune response of plants, but also leads to the production of disease-resistant crops. However, it has not been clarified that what molecular mechanism is stimulated in response to pathogen challenge. Our studies suggested that the SOG1 transcription factor, which plays a central role in the DNA damage response of plants, plays a crucial role in the defense response to pathogens.

Academic Significance and Societal Importance of the Research Achievements

植物は細菌、糸状菌、ウイルスなどさまざまな病原体の脅威に常にさらされている。本研究は、病原菌感染による植物の制御機構を理解することで、病原菌感染に対する植物特異的な応答機構を明らかにし、植物独自の環境応答統御システムを分子レベルで解明する点に意義を持つ。さらに、病原菌感染に対する植物の防御応答機構を自在に制御することで、耐病性技術や新しい植物生産技術の開発へ大きく貢献することが期待される。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (11 results)

All 2019 2018 2017

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (7 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Gap 2 phase: making the fundamental decision to divide or not2019

    • Author(s)
      Umeda Masaaki、Aki Shiori S、Takahashi Naoki
    • Journal Title

      Current Opinion in Plant Biology

      Volume: 51 Pages: 1-6

    • DOI

      10.1016/j.pbi.2019.03.001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis2019

    • Author(s)
      Takahashi Naoki、Ogita Nobuo、Takahashi Tomonobu、Taniguchi Shoji、Tanaka Maho、Seki Motoaki、Umeda Masaaki
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.43944

    • NAID

      120006619181

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identifying the target genes of SUPPRESSOR OF GAMMA RESPONSE 1, a master transcription factor controlling DNA damage response in Arabidopsis.2018

    • Author(s)
      Ogita N, Okushima Y, Tokizawa M, Yamamoto YY, Tanaka M, Seki M, Makita Y, Matsui M, Okamoto-Yoshiyama K, Sakamoto T, Kurata T, Hiruma K, Saijo Y, Takahashi N, Umeda M.
    • Journal Title

      The Plant Journal

      Volume: - Issue: 3 Pages: 439-453

    • DOI

      10.1111/tpj.13866

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage2017

    • Author(s)
      Chen Poyu、Takatsuka Hirotomo、Takahashi Naoki、Kurata Rie、Fukao Yoichiro、Kobayashi Kosuke、Ito Masaki、Umeda Masaaki
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 635-635

    • DOI

      10.1038/s41467-017-00676-4

    • NAID

      120006354238

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] ストレスに応答した細胞周期停止の制御機構の解明2019

    • Author(s)
      高橋直紀、荻田伸夫、高橋知伸、谷口昌司、梅田正明
    • Organizer
      第60回日本植物生理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ストレスに応答した細胞周期停止におけるANAC044およびANAC085の役割の解析2019

    • Author(s)
      高橋知伸、荻田伸夫、谷口昌司、高橋直紀、梅田正明
    • Organizer
      第60回日本植物生理学会年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 植物のストレスに応答した細胞周期停止の分子機構2018

    • Author(s)
      高橋直紀、荻田伸夫、梅田正明
    • Organizer
      日本遺伝学会第90回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] DNA damage activates two distinct signaling pathways controlling DNA repair and cell cycle arrest2018

    • Author(s)
      Naoki Takahashi, Nobuo Ogita, Masaaki Umeda
    • Organizer
      Plant Genome Stability and Change 2018
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Molecular analyses of CFI 25 in plant 3’-UTR length determination2018

    • Author(s)
      Xiaojuan Zhang, Naoki Takahashi, Masaaki Umeda, Marta Garcia-Leon, Vicente Rubio, Mika Nomoto, Yasuomi Tada, Tsuyoshi Furumoto, Takashi Aoyama, Tom Tsuge
    • Organizer
      日本光生物学協会 第20回年会
    • Related Report
      2018 Annual Research Report
  • [Presentation] ANAC044およびANAC085はDNA損傷による細胞周期の停止に重要な役割を果たす2018

    • Author(s)
      高橋直紀、荻田伸夫、高橋知伸、谷口昌司、梅田正明
    • Organizer
      第59回日本植物生理学会年会
    • Related Report
      2017 Research-status Report
  • [Presentation] DNA damage activates two distinct signaling pathways controlling DNA repair and cell cycle arrest2018

    • Author(s)
      Naoki Takahashi, Nobuo Ogita, Masaaki Umeda
    • Organizer
      Plant Genome Stability and Change
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2020-03-30  

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