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Development of new evaluation method for inhaled medicines adherence and construction of compliance system

Research Project

Project/Area Number 17K15753
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical sociology
Research InstitutionKurume University

Principal Investigator

Imamura Youhei  久留米大学, 医学部, 助教 (10529324)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords吸入アドヒアランス / 気管支喘息 / 慢性閉塞性肺疾患 / 内服アドヒアランス / COPD / 高齢者
Outline of Final Research Achievements

Inhaled medicines plays a central role in the treatment of bronchial asthma (asthma) and chronic obstructive pulmonary disease (COPD). However, inhalation medicines differs from oral medicines, and there are many different devices, and it is nessesary to understanding of their handling, techniques and dosages. The complexity of inhaled medicines leads to reduced adherence, and then which may lead to reduced levels of disease control and wasted medical costs.
This study will elucidate the reality of inhaled medicines adherence in patients with asthma and COPD. And we aim to build a system to enlighten inhaled medicines.

Academic Significance and Societal Importance of the Research Achievements

日本人のCOPDとぜん息患者の吸入薬アドヒアランスに対する障壁をASK-20質問表を用いて検討した。その結果、経口薬に対して吸入薬の独立したアドヒアランスバリアは、同じ吸入薬を使用するCOPDとぜん息患者ではそのアドヒアランスに対する障壁の内容が異なった。今回のこれらの結果は、吸入薬アドヒアランスにおける障害因子の特定化や患者の個別教育に役立つと考えられた。本システムの構築がなされれば、吸入薬アドヒアランスの更なる向上が望め、医療費の無駄を削減できると考えている。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (4 results)

All 2019 2018 2017

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Funded Workshop (1 results)

  • [Journal Article] Differences in Adherence Barriers to Inhaled Medicines between Japanese Patients with Chronic Obstructive Pulmonary Disease and Asthma Evaluated using the "Adherence Starts with Knowledge 20" (ASK-20) Questionnaire2019

    • Author(s)
      Toyama Takayuki、Kawayama Tomotaka、Kinoshita Takashi、Imamura Yohei、Yoshida Makoto、Takahashi Koichiro、Fujii Kazuhiko、Higashimoto Ikkou、Hoshino Tomoaki
    • Journal Title

      Internal Medicine

      Volume: 58 Issue: 2 Pages: 175-185

    • DOI

      10.2169/internalmedicine.0488-17

    • NAID

      130007579753

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-01-15
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Adherence barriers to inhaled medicines in Japanese older patients with asthma evaluated using the “Adherence Starts with Knowledge 20” (ASK-20) questionnaire2018

    • Author(s)
      Sasaki Jun、Kawayama Tomotaka、Yoshida Makoto、Takahashi Koichiro、Fujii Kazuhiko、Machida Kentaro、Kinoshita Takashi、Hoshino Tomoaki、and the Kyushu Asthma Seminar Investigators
    • Journal Title

      Journal of Asthma

      Volume: 56 Issue: 6 Pages: 632-641

    • DOI

      10.1080/02770903.2018.1484132

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Poor pharmacological adherence to inhaled medicines compared with oral medicines in Japanese patients with asthma and chronic obstructive pulmonary disease2017

    • Author(s)
      Imamura Y, Kawayama T, Kinoshita T, Sakazaki Y, Yoshida M, Takahashi K, Fujii K, Ando M, Hoshino T, Iwanaga T, Kohrogi H; Kyushu Asthma Seminar Investigators.
    • Journal Title

      Allergology International

      Volume: 66 Issue: 3 Pages: 482-484

    • DOI

      10.1016/j.alit.2016.10.008

    • NAID

      130005858878

    • ISSN
      1323-8930, 1440-1592
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Funded Workshop] ERS International Congress 20182018

    • Related Report
      2018 Annual Research Report

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Published: 2017-04-28   Modified: 2020-03-30  

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