| Project/Area Number |
17K15864
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical and hospital managemen
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| Research Institution | Kansai Medical University |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | POT法 / MRSA / 院内感染対策 / 医療関連感染症 / 分子疫学検査 / 医療関連感染対策 / 院内感染管理 |
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| Outline of Final Research Achievements |
Using the POT method, which is a molecular epidemiological test, the current status of MRSA nosocomial infections at three critical care centers was tested and verified. Each inspection was conducted in 2019. Although the number of MRSA detections and the condition of nosocomial infections at each critical care center were different, it was proved that there were nosocomial infections. In a study by medical staff, a certain number of MRSA carriers were confirmed, but MRSA of a genotype common to patients was not detected. This study is a limited period of one year, and we would like to lead to further verification and future measures by following up MRSA in the hospital in the long term.
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| Academic Significance and Societal Importance of the Research Achievements |
MRSA感染は様々な感染症の中でも、医療従事者の手などを介して感染が拡大し、検出率の高いことから、院内感染対の重要な指標である。今回我々は複数の救命センターにおけるMRSA感染の現状を明らかにし、医療従事者が保菌するMRSAが院内感染に与える影響を検証した。救命センターにおいて数の違いはあるものの全てのセンターで院内感染が存在することが分かった。また、患者と医療従事者から検出されたMRSAに共通する遺伝子型は認められず、患者―医療従事者間での感染は証明できなかったが、医療従事者の保菌するMRSAが院内感染に関与していることを否定しきれてはいない。本研究・内容は引き続き検証していく必要がある。
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