| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Outline of Final Research Achievements |
Animal studies have shown that leptin, secreted from adipose tissue, contributes to the promotion of bone resorption and suppression of bone formation through activation of the sympathetic nervous system. However, the relationship between leptin and sarcopenia/frailty has not been fully elucidated. We reported that plasma leptin concentrations are associated with radial cortical bone thickness in type 2 diabetic patients, independent of various background factors. These results indicate that leptin is associated with sarcopenia and frailty.
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