Compensation filter design method for BNCT to achieve optimal dose distribution
| Project/Area Number |
17K17838
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical Physics and Radiological Technology
Quantum beam science
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| Research Institution | Kyoto University |
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Principal Investigator |
Takata Takushi 京都大学, 複合原子力科学研究所, 助教 (60444478)
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| Project Period (FY) |
2017-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Keywords | BNCT / 治療計画 / 補償フィルター / ボーラス / 最適化 / 3Dプリンタ / 粒子線治療学 / 量子ビーム医療応用 |
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| Outline of Final Research Achievements |
In Boron Neutron Capture Therapy (BNCT), compensation filters are sometimes used to enhance the dose distribution near the neutron incident surface. This study suggests a technique for creating the shape of a compensation filter to achieve the most effective dose distribution. This approach shows that using a filter with an optimized shape can maximize the dose to the tumor target while minimizing the dose to healthy tissues.
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| Academic Significance and Societal Importance of the Research Achievements |
BNCTの臨床照射では、従来、矩形や円形といった単純な形状の補償フィルターが用いられおり、その厚さや体表面への配置は経験に基づいて決定されている。本研究で確立した補償フィルターの形状最適化を臨床適用することで、個々の症例毎に最適化された治療照射が可能となる。本研究の成果は、治療効果を最大限に発揮し、かつ、より安全性の高いBNCTの実現に繋がるものと考える。
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Report
(7 results)
Research Products
(17 results)
