A study on the usefulness of intestinal blood flow measurement by ultrasonic Doppler examination in pediatric gastrointestinal disorders

• Project/Area Number: 17K18108
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Pediatrics; Radiation science
• Research Institution: Juntendo University
• Principal Investigator: Jimbo Keisuke 順天堂大学, 医学部, 助教 (80772350)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 腹部超音波検査 / ドップラー検査 / 腸管血流 / vessel density / vascular index / 小児 / 消化器疾患 / power doppler / SMI / Vascular Index

Outline of Final Research Achievements

(1) Using a Doppler test in combination with abdominal ultrasonography, the quantified value (vessel density) of intestinal blood flow is more useful for diagnosing non-IgE-dependent infantile gastrointestinal allergy than other serological tests.
(2) It was suggested that quantifying intestinal blood flow signals by abdominal ultrasonography may be useful in predicting the severity of Kawasaki's disease.

Academic Significance and Societal Importance of the Research Achievements

腹部超音波監査は侵襲がなく、放射線被ばくを伴わない検査ツールであり、今回の検討は、小児消化器疾患の診療における超音波検査の役割を、より重要なものとするきっかけとなり得る。

Research Products

• [Journal Article] Ultrasonographic study of intestinal Doppler blood flow in infantile non-IgE-mediated gastrointestinal food allergy (2019)
  • Author(s): Jimbo K, Ohtsuka Y, Kono T, Arai N, Kyoudo R, Hosoi K, Aoyagi Y, Kudo T, Asai N, Shimizu T
  • Journal Title: Allergology International Volume: 68 Issue: 2 Pages: 199-206
  • DOI: 10.1016/j.alit.2018.08.010
  • NAID: 130007633576
  • ISSN: 1323-8930, 1440-1592
  • Peer Reviewed / Open Access