Role of embryonic muscle as hematopoietic niche
| Project/Area Number |
17K19530
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical structure and function and related fields
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| Research Institution | Kyushu University |
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Principal Investigator |
Sugiyama Daisuke 九州大学, 先端融合医療創成センター, 教授 (00426652)
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| Project Period (FY) |
2017-06-30 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 造血ニッチ / 造血幹細胞 / 胎生期造血細胞 / ニッチ / 筋肉 / 肥満細胞 / 胎仔筋組織 |
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| Outline of Final Research Achievements |
Hematopoietic stem and progenitor cells (HPSCs) are regulated and maintained by microenvironment and are thought to expand in fetal liver and spleen, and then move to bone marrow before birth. On the other hand, we found that c-kit+ HSPCs exist in muscle tissue (Tanaka et al., PLoS One, 2015).
Hereinafter, it will not be disclosed for a certain period of time due to patent applications.
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| Academic Significance and Societal Importance of the Research Achievements |
特許出願の関係上一定期間非公開とする。
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Report
(2 results)
Research Products
(1 results)
