Role of embryonic muscle as hematopoietic niche

Research Project

Project/Area Number	17K19530
Research Category	Grant-in-Aid for Challenging Research (Exploratory)
Allocation Type	Multi-year Fund
Research Field	Biomedical structure and function and related fields
Research Institution	Kyushu University
Principal Investigator	Sugiyama Daisuke 九州大学, 先端融合医療創成センター, 教授 (00426652)
Project Period (FY)	2017-06-30 – 2019-03-31
Project Status	Completed (Fiscal Year 2018)
Budget Amount *help	¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000) Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000) Fiscal Year 2017: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywords	造血ニッチ / 造血幹細胞 / 胎生期造血細胞 / ニッチ / 筋肉 / 肥満細胞 / 胎仔筋組織
Outline of Final Research Achievements	Hematopoietic stem and progenitor cells (HPSCs) are regulated and maintained by microenvironment and are thought to expand in fetal liver and spleen, and then move to bone marrow before birth. On the other hand, we found that c-kit+ HSPCs exist in muscle tissue (Tanaka et al., PLoS One, 2015). Hereinafter, it will not be disclosed for a certain period of time due to patent applications.
Academic Significance and Societal Importance of the Research Achievements	特許出願の関係上一定期間非公開とする。

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(2 results)