• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Biomedical application of steam-air micromist jet spray with disinfectants

Research Project

Project/Area Number 17K19861
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Society medicine, Nursing, and related fields
Research InstitutionNational Defense Medical College

Principal Investigator

Ishihara Masayuki  防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 防衛医学研究センター 医療工学研究部門, 教授 (10508500)

Co-Investigator(Kenkyū-buntansha) 中村 伸吾  防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 防衛医学研究センター 医療工学研究部門, 講師 (00505323)
藤田 真敬  防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 防衛医学研究センター 異常環境衛生研究部門, 教授 (20525927)
加來 浩器  防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 防衛医学研究センター 広域感染症学・制御研究部門, 教授 (40431499)
Project Period (FY) 2017-06-30 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2018: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywords洗浄技術 / ミストジェット噴射洗浄器 / 殺菌剤 / 貝殻焼成生石灰 / 除染技術 / 水蒸気マイクロミストジェット噴射洗浄器 / 帆立貝殻由来生石灰 / 洗浄 / 除染 / 病原微生物 / 有害化学物質 / 次亜塩素酸 / ホタテ貝殻由来生石灰 / 消毒 / 感染症防護 / 環境衛生 / 除染洗浄
Outline of Final Research Achievements

Application of a high-velocity steam-air micromist jet spray (HVS-AMJS) with disinfectants for cleansing the skin is proposed. Low-pressure steam is mixed with compressed air in a nozzle and then sprayed onto a surface of skin or material located approximately 22 cm from the nozzle. The temperature on the sprayed surface was controlled between 40ºC and 43 ºC. The HVS-AMJS with tap water effectively removed normal bacterial flora from contaminated wooden pieces, pig skin pieces, and pig skin wounds. Furthermore, the cleansing efficacy increased by advanced-treating with heated bio-shell calcium oxide powder (BiSCaO), hypochlorous acid, sodium hypochlorite, povidone iodine, or chlorhexidine gluconate. Especially, the HVS-AMJS combined with BiSCaO had higher bactericidal activity than when combined with other disinfectants. This study suggests that application of the HVS-AMJS with disinfectants, especially BiSCaO, may be useful for skin cleansing and environmental hygiene.

Academic Significance and Societal Importance of the Research Achievements

消臭効果を有し、各種ウィルス、病原菌、真菌を瞬時に不活性化及び殺菌することが知られているホタテ貝殻由来生石灰(BiSCaO)懸濁水を汎用除染、消毒剤としての用途の他、動物の壊疽や褥瘡を含む化膿性・難治性創傷の洗浄・治療法としての高速水蒸気ミストジェット噴射洗浄への併用・適用が可能となった。本研究での洗浄・消毒手段は、物理的消毒と化学的除去を併せ持った除染方法となり、既存の方法では達成が難しかった対象部位に強固に付着した微生物、バイオフィルム、デンタルプラーク、或いはエンドトキシンや各種有毒物質の除去が可能となると期待される。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (10 results)

All 2019 2018 2017

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (4 results)

  • [Journal Article] Comparison of various disinfectsnts on bactericidal acitivity under organic matter contaminated environments.2019

    • Author(s)
      Sato Y, Ishihara M, Fukuda K, Nakamura S, Murakami Y, Fujita M, Yokoe H.
    • Journal Title

      BioControl Science

      Volume: In press

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Disinfection of pseudomonas-infected wounds in diabetic db/db mice by weakly acidic hypochlorous acid.2018

    • Author(s)
      Kuwabara M, Ishihara M, Fukuda K, Nakamura S, Murakami K, Sato Y, Yokoe H, Kiyosawa T.
    • Journal Title

      Wound Medicine

      Volume: 23 Pages: 1-5

    • DOI

      10.1016/j.wndm.2018.09.001

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Behavior of Nitrate-Nitrogen and Nitrite-Nitrogen in Drinking Water2018

    • Author(s)
      Sato Y, Ishihara M, Fukuda K, Nakamura S, Murakami Y, Fujita M, Yokoe H.
    • Journal Title

      Biocontrol Science

      Volume: 23 Issue: 3 Pages: 139-143

    • DOI

      10.4265/bio.23.139

    • NAID

      130007485548

    • ISSN
      1342-4815, 1884-0205
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Behavior of Nitrate-Nitrogen and Nitrite-Nitrogen in Drinking Water2018

    • Author(s)
      Sato Y, Ishihara M, Fukuda K, Nakamura S, Murakami K, Fujita M, Yokoe H.
    • Journal Title

      Biocontrol Research In press

      Volume: 印刷中

    • NAID

      130007485548

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Stability of Weakly Acidic Hypochlorous Acid Solution with Microbicidal Activity2017

    • Author(s)
      Ishihara Masayuki、Murakami Kaoru、Fukuda Koichi、Nakamura Shingo、Kuwabara Masahiro、Hattori Hidemi、Fujita Masanori、Kiyosawa Tomoharu、Yokoe Hidetaka
    • Journal Title

      Biocontrol Science

      Volume: 22 Issue: 4 Pages: 223-227

    • DOI

      10.4265/bio.22.223

    • NAID

      130006285032

    • ISSN
      1342-4815, 1884-0205
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cleansing technique using high-velocity steam?air micromist jet spray2017

    • Author(s)
      Fukuda Koichi、Ishihara Masayuki、Murakami Kaoru、Nakamura Shingo、Sato Yoko、Kuwabara Masahiro、Fujita Masanori、Kiyosawa Tomoharu、Yokoe Hidetaka
    • Journal Title

      Journal of Medical Engineering & Technology

      Volume: 41 Issue: 7 Pages: 522-528

    • DOI

      10.1080/03091902.2017.1364309

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 様々な消毒剤の殺菌活性比較2018

    • Author(s)
      佐藤洋子、中村伸吾、高山智宏、後藤寿美代、安藤尚子、福田孝一、藤田真敬、石原雅之
    • Organizer
      日本防菌防黴学会 第45回年次大会  (東京、船堀)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 銀ナノ粒子含有複合材料による殺微生物・ウイルス不活化効果2017

    • Author(s)
      中村伸吾、佐藤洋子、石原雅之
    • Organizer
      日本防菌・防黴学会、第44回年次大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 大腸菌群および一般生菌の増殖と光照射による飲料水中の亜硝酸態窒素の挙動分析2017

    • Author(s)
      佐藤洋子、中村伸吾、石原雅之
    • Organizer
      日本防菌・防黴学会、第44回年次大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 水蒸気・空気混相マイクロミストジェット噴射による洗浄―その医療・獣医療応用への基礎的研究2017

    • Author(s)
      福田孝一、中村伸吾、石原雅之
    • Organizer
      日本防菌・防黴学会、第44回年次大会
    • Related Report
      2017 Research-status Report

URL: 

Published: 2017-07-21   Modified: 2020-03-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi