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Molecular mechanism underlying metameric morphogenesis

Research Project

Project/Area Number 18107006
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Developmental biology
Research Institution大学共同利用機関法人自然科学研究機構(岡崎共通研究施設) (2010)
National Institutes of Natural Sciences Okazaki Research Facilities (2006-2009)

Principal Investigator

TAKADA Shinji  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 教授 (60206753)

Co-Investigator(Kenkyū-buntansha) KOSHIDA Sumito  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 (40342638)
OHKUBO Tadashi  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 (10450719)
Co-Investigator(Renkei-kenkyūsha) YABE Taijiro  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教 (30470074)
AKANUMA Takashi  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 研究員 (50450721)
KAWAMURA Akinori  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 学振特別研究員 (10466691)
TAKADA Ritsuko  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 研究員 (40450720)
Research Collaborator UTSUMI Hideko  基礎生物学研究所, 分子発生学研究部門, 技術職員
CHEN Quihong  大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 研究員
TAKAHASHI Jun  総合研究大学院大学, 大学院生
TSUNOKUNI Hiroyuki  総合研究大学院大学, 大学院生
WANGLAR Chimwar  総合研究大学院大学, 大学院生
Project Period (FY) 2006 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥111,020,000 (Direct Cost: ¥85,400,000、Indirect Cost: ¥25,620,000)
Fiscal Year 2010: ¥21,710,000 (Direct Cost: ¥16,700,000、Indirect Cost: ¥5,010,000)
Fiscal Year 2009: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000)
Fiscal Year 2008: ¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2007: ¥21,710,000 (Direct Cost: ¥16,700,000、Indirect Cost: ¥5,010,000)
Fiscal Year 2006: ¥24,440,000 (Direct Cost: ¥18,800,000、Indirect Cost: ¥5,640,000)
Keywords発生・分化 / 細胞・組織 / 遺伝子 / 発現制御 / シグナル伝達 / 体節 / 転写調節 / 形態形成 / 咽頭弓 / 発生 / 脊椎動物 / 転写制御 / 変異体 / ノックアウト
Research Abstract

To understand the molecular mechanism underlying the development of metameric structures, we identified several genes required for somite segmentation. One of these genes, Ripply1, represses the function of T-box transcription factors through several ways, resulting in proper positioning of the segmentation boundary. Furthermore, the interaction between Ripply and T-box factors also appears to be required for the segmentation of another metameric structure, the pharyngeal arch, suggesting that a common machinery is involved in segmentation of different tissues.

Report

(6 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (58 results)

All 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article (29 results) (of which Peer Reviewed: 23 results) Presentation (23 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice2011

    • Author(s)
      Okubo, T., Kawamura, A., Takahashi, J., Yagi, H., Morishima, M., Matsuoka, R., & Takada, S.
    • Journal Title

      Development

      Volume: 138 Pages: 339-348

    • Related Report
      2010 Annual Research Report 2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite2010

    • Author(s)
      Takahashi J., Ohbayashi A., Oginuma M., Saito D., Mochizuki A., Saga Y., & Takada S.
    • Journal Title

      Dev. Biol

      Volume: 342 Pages: 134-145

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Planar polarization of node cells determines the rotational axis of node cilia2010

    • Author(s)
      Hashimoto, H., Shinohara, K., Wang, J., Ikeuchi. S., Yoshiba, S., Meno, C., Nonaka, S., Takada, S., Hatta, K., Wynshaw-boris, A., & Hamada, H.
    • Journal Title

      Nat Cell Biol

      Volume: 12 Pages: 170-176

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor(Cfr) and delta-like protein(Dlk)2010

    • Author(s)
      Miyaoka, Y., Tanaka, M., Imamura, T., Takada, S., & Miyajima, A.
    • Journal Title

      Development

      Volume: 137 Pages: 159-167

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite2010

    • Author(s)
      Takahashi J., 他(7名中7番目)
    • Journal Title

      Dev.Biol.

      Volume: 342 Pages: 134-145

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating dishevelled polymerization2010

    • Author(s)
      Nishita M, 他(10名中8番目)
    • Journal Title

      Mol Cell Biol.

      Volume: 30 Pages: 3610-3619

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Planar polarization of node cells determines the rotational axis of nodecilia2010

    • Author(s)
      Hashimoto, H., 11名中8番目
    • Journal Title

      Nat.Cell Biol.

      Volume: 12 Pages: 170-176

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor (Cfr) and delta-like protein (Dlk)2010

    • Author(s)
      Miyaoka Y., 他(5名中4番目)
    • Journal Title

      Development

      Volume: 137 Pages: 159-167

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Motor neurons with axial muscle projections specified by Wnt4/5 signaling2009

    • Author(s)
      Agalliu D, Takada S, Agalliu I, McMahon AP, Jessell TM.
    • Journal Title

      Neuron 61

      Pages: 708-720

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators2008

    • Author(s)
      Kawamura, A., Koshida, S., & Takada, S.
    • Journal Title

      Mol. Cell Biol

      Volume: 28 Pages: 3236-3244

    • NAID

      120006385748

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Wnt canonical pathway restricts graded Shh/Gli patterning activity through the regulation of Gli3 expression2008

    • Author(s)
      Alvarez-Medina, R., Cayuso, J., Okubo, T., Takada, S., & Marti, E.
    • Journal Title

      Development

      Volume: 135 Pages: 237-247

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activator-to-repressor conversion of T-boxtranscription factors by the Ripply family ofGroucho/TLE-associated mediators2008

    • Author(s)
      Kawamura, A., Koshida, S., & Takada, S.
    • Journal Title

      Mol. Cell Biol 28

      Pages: 3236-3244

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Activator-to-repressor conversion of T-box transcription factors by the Ripply family of Groucho/TLE-associated mediators2008

    • Author(s)
      Kawamura, A., Koshida, S., Takada, S.
    • Journal Title

      Mol Cell Biol. 28

      Pages: 3236-3244

    • NAID

      120006385748

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stabilized {beta}-Catenin Functions through TCF/LEF Proteins and the Notch/RBP-J{kappa} Complex To Promote Proliferation and Suppress Differentiation of Neural Precursor Cells2008

    • Author(s)
      Shimizu T, Kagawa T, Inoue T, Nonaka A, Takada S, A buratani H, Taga T.
    • Journal Title

      Mol Cell Biol. 28

      Pages: 7427-7441

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Wnt canonical pathway restricts graded Shh/Gli patterning activity throug h the regulation of Gli3 expression2008

    • Author(s)
      Alvarez-Medina, R., Cayuso, J., O kubo, T., Takada, S., & Marti, E
    • Journal Title

      Development 135

      Pages: 237-247

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Paf1 complex homologes are required for Notch-regulated transcription during somite segmentation2007

    • Author(s)
      Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., & Takada, S.
    • Journal Title

      EMBO Rep

      Volume: 8 Pages: 858-863

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Paf1 complexhomologes are required for Notch-regulated transcription during somite segmentation2007

    • Author(s)
      Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., Takada, S.
    • Journal Title

      EMBO Rep 8

      Pages: 858-863

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Paf1 complex homologes are required for Notch-regulated transcription du ring somite segmentation2007

    • Author(s)
      Akanuma, T., Koshida, S., Kawamura, A., Kishimoto, Y., & Takada, S.
    • Journal Title

      EMBO Rep 8

      Pages: 858-863

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation2007

    • Author(s)
      Takada, I., 他 19人中15番目
    • Journal Title

      Nat.Cell Biol 9

      Pages: 1273-1285

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impairment of the ubiquitin-proteasome system by cellular FLIP2007

    • Author(s)
      Ishioka, T., 他 10人中5番目
    • Journal Title

      Genes Cells 12

      Pages: 735-744

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monounsaturated fatty acid modification of Wnt proteins : Its role in Wnt secretion2006

    • Author(s)
      Takada, R., Satomi, Y., Kurata, T., Ueno, N., Norioka, S., Kondoh, H., Takao, T., & Takada, S.
    • Journal Title

      Dev. Cell

      Volume: 11 Pages: 791-801

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse2006

    • Author(s)
      Yamaguchi, Y., Yonemura, S., & Takada, S.
    • Journal Title

      Development

      Volume: 133 Pages: 4737-4748

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Monounsaturated fatty acid modification of Wnt proteins : Its role in Wnt secretion.2006

    • Author(s)
      Takada, R., Satomi, Y., Kurata, T., Ueno, N., Norika, S., Kondoh, H., Takao, T., Takada,S.
    • Journal Title

      Dev.Cell 11

      Pages: 791-801

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced dell migration2006

    • Author(s)
      Nishita, M., Yoo, S.K, Nomachi, A., Kani, S., Sougawa, N., Ohta, Y., Takada, S., Kikuchi, A., Minami,Y
    • Journal Title

      J.Cell Biol. 175

      Pages: 552-562

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.2006

    • Author(s)
      Horiuchi, K., Umetani, M., Minami, T., Okayama, H., Takada, S., Yamamoto, M., Aburatani, H., Reid, P.C., Housman, D.E, Hamakubo, T., Kodama,T.
    • Journal Title

      Proc Natl Acad Sci USA. 103

      Pages: 17278-17283

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Grainyhead-related transcription factor is required for duct maturation in the salivary gland and the kidney of the mouse.2006

    • Author(s)
      Yamaguchi Y., Yonemura, S., Takada, S.
    • Journal Title

      Development 133

      Pages: 4737-4748

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Determinative role of Wnt signals in dorsal iris-derived lens regeneration in newt eye.2006

    • Author(s)
      Hayashi, T., Mizuno, N., Takada, R., Takada, S., Kondoh,H.
    • Journal Title

      Mech Dev. 123

      Pages: 793-800

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin.2006

    • Author(s)
      Inoue T, Kagawa T, Fukushima M, Shimizu T, Yoshinaga Y, Takada S, Tanihara H, Taga T
    • Journal Title

      Stem Cells. 24

      Pages: 95-104

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Deficiency of Porcupine, an O-acyltransferase gene, impairs convergent extension during gastrulation in zebrafish embryos and does not affect equivalently the trafficking of different Wnt proteins

    • Author(s)
      Chen, Q, 他(3名中3番目)
    • Journal Title

      J.Cell Sci.

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Jagged/Notch is required for epithelial organization and maintenance of assembled fibronectin during pharyngeal morphogenesis, in Exiting Biologies : Biology at the interface2011

    • Author(s)
      Takada S
    • Place of Presentation
      RIKEN CDB, Kobe
    • Year and Date
      2011-09-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Jagged/Notch is required for epithelial organization and maintenance of assembled fibronectin during pharyngeal morphogenesis2011

    • Author(s)
      Shinji Takada
    • Organizer
      Cell Symposium, Exciting Biologies: Biology at the interface
    • Place of Presentation
      理研CDB(兵庫県)
    • Year and Date
      2011-09-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] ゼブラフィッシュの咽頭嚢形成における上皮組織の再組織化2011

    • Author(s)
      高田慎治
    • Organizer
      第84回日本生化学会(シンポジウム)
    • Place of Presentation
      京都国際会館(京都府)
    • Year and Date
      2011-09-22
    • Related Report
      2010 Final Research Report
  • [Presentation] ゼブラフィッシュの咽頭嚢形成における上皮組織の再組織化2011

    • Author(s)
      高田慎治
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都国際会館(京都府)
    • Year and Date
      2011-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Jagged/Notch regulates epithelial morphogenesis during the development of pharyngeal pouch2011

    • Author(s)
      Takada S
    • Organizer
      The 5th Asia-Oceania Zebrafish Meeting
    • Place of Presentation
      Beijing
    • Year and Date
      2011-08-27
    • Related Report
      2010 Final Research Report
  • [Presentation] Jagged/Notch regulates epithelial morphogenesis during the development of pharyngeal pouch2011

    • Author(s)
      Shinji Takada
    • Organizer
      The 5th Asia-Oceania Zebrafish Meeting
    • Place of Presentation
      中国、北京市
    • Year and Date
      2011-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Jagged/Notch directs epithelial reorganization and assembly of Fibronectin during pharyngeal pouch morphogenesis2011

    • Author(s)
      Hiroyuki Tsunokuni, Takashi Akanuma, Shinji Takada
    • Organizer
      The 7th European Zebrafish Meeting
    • Place of Presentation
      英国、Edingburgh
    • Year and Date
      2011-07-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] 体節の分節位置を決定するTbx6タンパク質の分解機構2010

    • Author(s)
      高橋潤、矢部泰二郎、高田慎治
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tbx1の抑制因子Ripply3はPax9の転写を抑制し咽頭弓の発生を制御する2010

    • Author(s)
      大久保直, 八木寿人、川村哲規、高橋潤、森島正恵、松岡瑠美子、高田慎治
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2010-12-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 咽頭弓と体節の発生におけるJaggedシグナルとフィブロネクチンの相互作用2010

    • Author(s)
      高田慎治
    • Organizer
      第62回日本細胞生物学会(シンポジウム)
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-05-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 咽頭弓と体節の発生におけるJaggedシグナルとフィブロネクチンの相互作用2010

    • Author(s)
      高田慎治
    • Organizer
      第62回日本細胞生物学会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Tbx-associated transcriptional corepressor Ripply3 is essential for pharyngeal arch development2008

    • Author(s)
      Okubo, T. Kawamura, A., Takahashi, J., Ohbayashi, A., & Takada, S.
    • Organizer
      第31回日本分子生物学会大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2008-12-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Specific lipidation and structure of secreted Wnt proteins2008

    • Author(s)
      Shinji Takada
    • Organizer
      OIST symposium on Gradient and Signalling : from chemotaxis to development
    • Place of Presentation
      沖縄
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Ripply3, a negative regulator of Tbx1, is required for development of caudal pharyngeal arches and their derivatives2008

    • Author(s)
      Takada S
    • Organizer
      Cold Spring Harbor Meeting on Mouse Molecular Genetics
    • Place of Presentation
      Cold Spring Harbor(USA)
    • Year and Date
      2008-10-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Ripply3, a negative regulator ofTbx1, is required for development of caudalpharyngeal arches and their derivatives2008

    • Author(s)
      Takada, S.
    • Organizer
      in Cold Spring Harbor Meeting on MousseMolecular Genetics
    • Place of Presentation
      Cold Spring Harbor, U.S.A.
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Tbx-associatedtranscriptional corepressor, Ripply3, playsessential roles in pharyngeal development2008

    • Author(s)
      Okubo, T. Kawamura, A., Takahashi, J., Ohbayashi, A., Takada, S.
    • Organizer
      inannual meeting of Society for DevelopmentalBiology, Philadelphia
    • Place of Presentation
      Philadelphia
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Roles of Wntless in zebrafish development2008

    • Author(s)
      Qiuhong Chen, Shinji Takada
    • Organizer
      第41回日本発生生物学会大会
    • Place of Presentation
      徳島
    • Related Report
      2008 Annual Research Report
  • [Presentation] Wnt proteins, modified with mono-unsaturated fatty acids, are secreted as self-assembled oligomers from cultured cells2008

    • Author(s)
      Ritsuko Takada, Shinji Takada
    • Organizer
      第60回日本細胞生物学会大会
    • Place of Presentation
      横浜
    • Related Report
      2008 Annual Research Report
  • [Presentation] Transcriptional repression of mesp gene via Groucho/TLE-associated mediator Ripply2007

    • Author(s)
      Takada S
    • Organizer
      Satellite meeting to the 66^<th> Annual Meeting of the Society for Developmental Biology and the First Pan-American Congress in Developmental Biology : Somitogenesis : from models to Therapeutics
    • Place of Presentation
      Cancun(Mexico)
    • Year and Date
      2007-06-16
    • Related Report
      2010 Final Research Report
  • [Presentation] Transcriptional repression ofmesp gene via Groucho/TLE-associatedmediator Ripply2007

    • Author(s)
      Takada, S
    • Organizer
      in Satellite meeting to the66^<th> Annual Meeting of the Society for Developmental Biology and the First Pan-American Congress in Developmental Biology : Somitogenesis : from models to Therapeutics
    • Place of Presentation
      Cancun (Mexico)
    • Year and Date
      2007-06-16
    • Related Report
      2008 Self-evaluation Report
  • [Presentation] Transcriptional repression of mesp gene via Groucho/TLE-associated mediator Ripply2007

    • Author(s)
      Takada, S.
    • Organizer
      the 66th Annual Meeting of the Society for Developmental Biology ans the First Pan-American Congress in Developmental Biology
    • Place of Presentation
      Cancun (Mexico)
    • Year and Date
      2007-06-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] Transcriptional repression of mesp-b gene by Groucho/TLE-associated mediator Ripply12007

    • Author(s)
      Kawamura, A., Koshida, S., & Takada, S.
    • Organizer
      第40回日本発生生物学会, 第59回日本細胞生物学会合同年会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2007-05-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] マウスripply3は咽頭弓内胚葉からの胸腺発生に必須である。2007

    • Author(s)
      大久 保直、川村 哲規、高橋 潤、大林 享子、高田 慎治
    • Organizer
      第30回日本分子生物学会, 第80回日本生化学会合同大会
    • Place of Presentation
      パシフィコ横浜
    • Related Report
      2007 Annual Research Report
  • [Book] 咽頭弓からの胸腺形成と先天性異常の発症機構2012

    • Author(s)
      大久保直、高田慎治
    • Related Report
      2010 Final Research Report
  • [Book] Groucho結合因子Ripply1による分節プログラムの制御2006

    • Author(s)
      川村哲規、越田澄人、高田慎治
    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.nibb.ac.jp/cib2/

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://www.nibb.ac.jp/cib2/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.nibb.ac.jp/cib2/

    • Related Report
      2008 Self-evaluation Report
  • [Remarks]

    • URL

      http://www.nibb.ac.jp/cib2/

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2006-04-01   Modified: 2016-04-21  

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