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Fluorescence endoscope for visualization of the placental vascular network

Research Project

Project/Area Number 18300178
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionNational Research Institute for Child Health and Development

Principal Investigator

CHIBA Toshio  National Research Institute for Child Health and Development, 臨床研究開発部, 部長 (20171944)

Co-Investigator(Kenkyū-buntansha) ENOSAWA Shin  国立成育医療センター(研究所), 実験外科研究室, 室長 (40232962)
MIWA Mitsuharu  浜松ホトニクス株式会社・中央研究所, 第7研究室, 主任部員 (90393983)
Co-Investigator(Renkei-kenkyūsha) ENOSAWA Shin  国立成育医療センター(研究所), 実験外科研究室, 室長 (40232962)
MIWA Mitsuharu  浜松ホトニクス株式会社・中央研究所, 第7研究室, 主任部員 (90393983)
Project Period (FY) 2006 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥17,990,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2008: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2007: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2006: ¥5,900,000 (Direct Cost: ¥5,900,000)
Keywords検査・診断システム / 内視鏡
Research Abstract

本研究では,臓器内部の血流,特に子宮内胎児手術の代表的な症例である,双胎間輸血症候群(TTTS)の胎盤吻合血管レーザ凝固術において,吻合血管の血流を可視化する蛍光内視鏡システムを開発した.本蛍光内視鏡にて妊娠ウサギの胎盤血流観察を行った結果,通常内視鏡より細かな血管像を確認することが可能であった.将来,この手法を用いることで双胎間の吻合血管の焼き残しなく,より適切な血管焼灼が可能となり,胎児予後の更なる改善が期待される.

Report

(4 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (13 results)

All 2009 2008 2007 2006 Other

All Journal Article (5 results) Presentation (5 results) Book (3 results)

  • [Journal Article] ICG fluorescence endoscope for visualization of the placental vascular network2009

    • Author(s)
      Kanako Harada, Mitsuharu Miwa, Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano, Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sankai
    • Journal Title

      Minimally Invasive therapy and Allied Technologies 18(1)

    • Related Report
      2008 Final Research Report
  • [Journal Article] New fluorescence endoscope for visualization of placental vascular network - feasibility study2007

    • Author(s)
      Kanako Harada, Mitsuharu Miwa, Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano, Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sankai
    • Journal Title

      IFMSS2007 the 26^<th> annual meeting of the International Fetal Medicine and Surgery Society 2007年3月採択(2007年4月 発表)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] 新しい硬性蛍光内視鏡とその胎児手術への応用2006

    • Author(s)
      千葉敏雄・草野満夫・原田香奈子・渡邉慎介・絵野沢伸・福与恒雄・前田英樹・三輪光春・鹿山貴弘・山海直
    • Journal Title

      第19回日本内視鏡外科学会雑誌 11

      Pages: 368-368

    • Related Report
      2008 Final Research Report
  • [Journal Article] 新しい硬性蛍光内視鏡とその胎手術への応用2006

    • Author(s)
      千葉敏雄, 草野靖夫, 原田香奈子, 渡邉慎介, 絵野沢伸, 福与恒雄, 前田英樹, 三輪光春, 鹿山貴弘, 山海直
    • Journal Title

      第19回日本内視鏡外科学会雑誌 Vol.11 No.7

      Pages: 368-368

    • Related Report
      2006 Annual Research Report
  • [Journal Article] ICG fluorescence endoscope for visualization of placental vascular network

    • Author(s)
      Kanako Harada, Mitsuharu Miwa, Tsuneo Fukuyo, Shin Enosawa, Toshio Chiba
    • Journal Title

      Surgical Endoscopy (in press)

    • Related Report
      2006 Annual Research Report
  • [Presentation] New fluorescence endoscope can visualize the detailed placental vascular network -a feasibility study-2007

    • Author(s)
      Akihiko Ishiyama, Hiromasa Yamashita, Kanako Harada, Mitsuharu Miwa , Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano,Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sankai
    • Organizer
      SMIT2007
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-20
    • Related Report
      2008 Final Research Report
  • [Presentation] New fluorescence endoscope can visualize the detailed placental vascular network-a feasibility study-2007

    • Author(s)
      Akihiko Ishiyama, Hiromasa Yamashita, Kanako Harada, MitSllharu Miwa, Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano, Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sanlcai
    • Organizer
      SMIT2007
    • Place of Presentation
      仙台
    • Year and Date
      2007-11-20
    • Related Report
      2007 Annual Research Report
  • [Presentation] TTTS治療における胎盤血管観察のための蛍光内視鏡2007

    • Author(s)
      石山昭彦, 原田香奈子, 三輪光春, 福与恒雄, 山下紘正, 中山智里, 宮本義孝, 千葉敏雄, 草野満夫, 絵野沢伸, 渡辺慎介, 前田英樹, 鹿山貴弘, 山海 直
    • Organizer
      胎児治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-19
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] New fluorescence endoscope for visualization of the placental vascular network - a feasibility study2007

    • Author(s)
      Kanako Harada, Mitsuharu Miwa, Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano, Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sankai
    • Organizer
      IFMSS2007
    • Place of Presentation
      Aruba, USA
    • Year and Date
      2007-05-01
    • Related Report
      2008 Final Research Report
  • [Presentation] New fluorescence endoscope fbr Visualization of the placental vascular network-afeasibility study2007

    • Author(s)
      Kanako Hamda, Mitsuharu Miwa, Tsuneo Fukuyo, Toshio Chiba, Mitsuo Kusano, Shin Enosawa, Shinsuke Watanabe, Hideki Maeda, Takahiro Shikayama, Tadashi Sankai
    • Organizer
      IFMSS2007
    • Place of Presentation
      Aruba, USA
    • Year and Date
      2007-05-01
    • Related Report
      2007 Annual Research Report
  • [Book] ICG蛍光Navigation surgeryのすべて2008

    • Author(s)
      石山昭彦, 千葉敏雄
    • Publisher
      株式会社インターメディカ
    • Related Report
      2008 Final Research Report
  • [Book] 胎児手術への応用、鏡視下手術との融合による新たな低侵襲性手術の展開、ICG蛍光 Navigation surgery のすべて(pp. 376-381)2008

    • Author(s)
      石山昭彦, 千葉敏雄
    • Total Pages
      383
    • Publisher
      株式会社インターメディカ
    • Related Report
      2008 Annual Research Report
  • [Book] 胎児内視鏡と胎盤血管造影、脈管造影-胎児内視鏡と胎盤血管造影、ICG蛍光 Navigation surgery のすべて(pp. 277-286)2008

    • Author(s)
      石山昭彦, 千葉敏雄
    • Total Pages
      383
    • Publisher
      株式会社インターメディカ
    • Related Report
      2008 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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