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Distribution, origin and evolution of Fasciola japonicum in eastern Asia

Research Project

Project/Area Number 18405035
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section海外学術
Research Field Basic veterinary science/Basic zootechnical science
Research InstitutionIwate University

Principal Investigator

ITAGAKI Tadashi  Iwate University, 農学部, 教授 (80203074)

Co-Investigator(Kenkyū-buntansha) SHIBAHARA Toshiyuki  千葉科学大学, 薬学部, 教授 (70116937)
AOKI Mikiko  岩手大学, 農学部, 助教 (20302060)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥10,100,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2007: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2006: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsFasciola / Asia / distribution / origin / evolution / 肝蛭 / 中国 / 単為生殖 / 両性生殖 / ITS1 / ND1 / ウシ / 分布 / 東アジア / 黄牛 / ヤク / 単為生殖型 / 両性生殖型
Research Abstract

Parthenogenic Fasciola species have been known in Japan and Korea. The present study showed that parthenogenic Fasciola sp. also distributed in Vietnam and mainland China, suggesting occurrence throughout Asian countries. Molecular and phylogenical studies based on nuclear ribosomal DNA (ITS1) and mitochondrial DNA (NDI gene) suggested that parthenogenic Fasciola forms came into existence by resulting from interspecific hybridyzation between F.hepatica and F.gigantica and following backcross with the two species, and that they acquired the ability of parthenogenesis. New born parthenogenic Fasciola forms spread out with final hosts such as domestic cattle into neighboring counties as Korea and Japan in the east and Vietnam in the south.

Report

(6 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (41 results)

All 2010 2009 2008 2007 2006

All Journal Article (16 results) (of which Peer Reviewed: 14 results) Presentation (18 results) Book (7 results)

  • [Journal Article] An Occurrence of Fungal Airsacculitis Associated with Severe Helminthiasis in a Black-eared Kite (Milvus migrans lineatus)2010

    • Author(s)
      Yoshihiko Sato, Tadashi Itagaki
    • Journal Title

      Avian Disease (in press)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Discrimination among the ITS1 types of Fasciola spp. based on PCR-RFLP method2010

    • Author(s)
      Madoka Ichikawa, Tadashi Itagaki
    • Journal Title

      Parasitology Research 106

      Pages: 757-761

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Discrimination among the ITS1 types of Fasciola spp.based on PCR-RFLP method2010

    • Author(s)
      Ichikawa, M., Itagaki, T.
    • Journal Title

      Parasitology Research 106

      Pages: 757-761

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An Occurrence of Fungal Airsacculitis Associated with Severe Helminth Infestiation in a Black-eared Kite(Milvus migrans lineatus)2010

    • Author(s)
      Sato, Y., Itagaki, T.
    • Journal Title

      Avian Diseases (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occurrence of spermic diploid and aspermic triploid forms of Fasciola in Vietnam and their molecular characterization based on nuclear and mitochondrial DNA2009

    • Author(s)
      Tadashi Itagaki, Keisuke Sakaguchi, Kunio Terasaki, Osamu Sasaki, Shinobu Yoshihara, Truong Van Dung
    • Journal Title

      Parasitology International 58

      Pages: 81-85

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of Fasciola hepatica, F. gigantica and aspermic Fasciola sp. in China based on nuclear and mitochondrial DNA2009

    • Author(s)
      Mao Peng, Mie Ichinomiya, Maiko Ohtori, Madoka Ichikawa, Toshiyuki Shibahara, Tadashi Itagaki
    • Journal Title

      Parasitology Research 105

      Pages: 809-815

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of Fasciola hepatica, Fasciola gigantica, and aspermic Fasciola sp.in China based on nuclear and ribosomal DNA.2009

    • Author(s)
      Peng, M., et al.
    • Journal Title

      Parasitology Research 105

      Pages: 809-815

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occurrence of spermic diploid and aspermic triploid forms of Fasciola in Vietnam and their molecular characterization based on nuclear and mitochondrial DNA2009

    • Author(s)
      Tadashi Itagaki, Keisuke Sakaguchi, Kunio Terasaki, Osamu Sasaki, Shinobu Yoshihara, Truong Van Dung
    • Journal Title

      Parasitol.Int 58

      Pages: 81-85

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Molecular characterization of Fasciola hepatica, F.gigantica and aspermic Fasciola sp.in China based on nuclear and mitochondrial DNA2009

    • Author(s)
      Mao Peng, Mie Ichinomiya, Maiko Ohtori, Madoka Ichikawa, Toshiyuki Shibahara, Tadashi Itagaki
    • Journal Title

      Parasitol Res (In press)

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 犬の Strongyloides sp. 感染症例に対するフェバンテル配合剤の治療効果2008

    • Author(s)
      伊藤直之, 村岡登, 河又淳, 青木美樹子, 板垣匡
    • Journal Title

      日本獣医師会誌 61

      Pages: 453-458

    • NAID

      10025574195

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 犬のStrongyloides sp.感染症例に対するフェバンテル配合剤の治療効果2008

    • Author(s)
      伊藤直之, 村岡登, 川又淳, 青木美樹子, 板垣匡
    • Journal Title

      日本獣医師会雑誌 61

      Pages: 453-458

    • NAID

      10025574195

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Occurrence of spermic diploid and aspermic triploid forms of Fasciola in Vietnam and their molecular characterzation based on nuclear and ribosomal DNA2008

    • Author(s)
      Itagaki, et.al.
    • Journal Title

      Parasitology International 58

      Pages: 81-85

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 犬のStrongyloides sp. 感染症例に対するフェバンテル配合剤の治療効果2008

    • Author(s)
      伊藤直之, ら
    • Journal Title

      日本獣医師会雑誌 61

      Pages: 453-458

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 飼育イヌの Giardia intestinalis 感染状況と分離株の遺伝子型2007

    • Author(s)
      伊藤直之, 板垣匡
    • Journal Title

      獣医寄生虫学会誌 5(2)

      Pages: 17-25

    • NAID

      120005522951

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 飼育イヌのGiardia intestinalis感染状況と分離株の遺伝子型.2007

    • Author(s)
      伊縢直之, 板垣 匡
    • Journal Title

      獣医寄生虫学会誌 5(2)

      Pages: 17-25

    • NAID

      120005522951

    • Related Report
      2006 Annual Research Report
  • [Journal Article] セラメクチンによるイヌセンコウヒセンタニ感染症例の治療.2006

    • Author(s)
      村岡 登, 伊藤直之, 青木美樹子, 板垣 匡
    • Journal Title

      日獣会誌 59

      Pages: 131-133

    • Related Report
      2006 Annual Research Report
  • [Presentation] 牛の寄生虫病:最近の基礎研究から2010

    • Author(s)
      板垣匡
    • Organizer
      日本獣医内科アカデミー日本獣医臨床病理学会2010年大会
    • Place of Presentation
      東京都新宿区京王プラザホテル
    • Year and Date
      2010-02-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] ザンビア共和国のウシおよびレチュエより得られたSetaria属線虫について2009

    • Author(s)
      田村愛子, ら
    • Organizer
      日本寄生虫学会・日本衛生動物学会北日本支部合同大会
    • Place of Presentation
      帯広市帯広畜産大学原虫病研究センター
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本産肝蛭の精子形成能およびDNA型の解析2009

    • Author(s)
      市川まどか, ら
    • Organizer
      日本寄生虫学会・日本衛生動物学会北日本支部合同大会
    • Place of Presentation
      帯広市帯広畜産大学原虫病研究センター
    • Year and Date
      2009-10-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウシにおけるGiardia intestinalis、Enterocytozoon bieneusiとEncephalitozoon intestinalisの分子学的疫学調査2009

    • Author(s)
      倉内ゆき, ら
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      鳥取市とりぎん文化会館
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] ウシにおけるEimeria属のオーシストの検出状況2009

    • Author(s)
      川西泰平, ら
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      鳥取市とりぎん文化会館
    • Year and Date
      2009-09-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中国産肝蛭の生殖型およびDNA型による特徴づけ : 長春市由来虫体について2009

    • Author(s)
      市川まどか, 柴原壽行, ペンモー, 板垣匡
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      とりぎん文化会館、鳥取県
    • Year and Date
      2009-09-25
    • Related Report
      2009 Final Research Report
  • [Presentation] 中国産肝蛭の生殖型およびDNA型による特徴づけ:長春市由来虫体について2009

    • Author(s)
      市川まどか, ら
    • Organizer
      第148回日本獣医学会学術集会
    • Place of Presentation
      鳥取市とりぎん文化会館
    • Year and Date
      2009-09-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Hybridyzation experiments indicate incomplete isolating mechanism between Fasciola hepatica and F. gigantica2009

    • Author(s)
      Tadashi Itagaki, Mie Ichinomiya, Kouichi Fukuda, Seigo Fusyuku, Carlos Carmona
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      コンベンションセンター, Calgary, Canada
    • Year and Date
      2009-08-11
    • Related Report
      2009 Final Research Report
  • [Presentation] Is the origin of parthenogenic Fasciola sp. in China? : A study of DNA types and morphology in Chineses Fasciola specimens2009

    • Author(s)
      Madoka Ichikawa, Mao Peng, Mie Ichinomiya, Maiko Ohtori, Toshiyuki Shibahara, Tadashi Itagaki
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      コンベンションセンター, Calgary, Canada
    • Year and Date
      2009-08-11
    • Related Report
      2009 Final Research Report
  • [Presentation] Hybridyzation experiments indicate incomplete isolating mechanism between Fasciola hepatica and F.gigantica.2009

    • Author(s)
      Itagaki, T., et al.
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      カナダ・カルガリー市コンベンションセンター
    • Year and Date
      2009-08-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular characterization of Dicrocoelium dendriticum and D.chinens is obtained from Japanese serow(Capricornis crispus)and sika deer(Cervus nippon)in Iwate, Japan2009

    • Author(s)
      Ohtori, M., et al.
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      カナダ・カルガリー市コンベンションセンター
    • Year and Date
      2009-08-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Is the origin of parthenogenic Fasciola sp.in China? : A study of DNA types and morphology in Chineses Fasciola specimens.2009

    • Author(s)
      Ichikawa, M., et al.
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      カナダ・カルガリー市コンベンションセンター
    • Year and Date
      2009-08-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] Prevalence and infectivity to experimental rodents of Trichinella sp.obtained from Japanese black bears in Iwate Prefecture, Japan2009

    • Author(s)
      Itagaki, T., et al.
    • Organizer
      World Association for the Advancement of Veterinary Parasitology
    • Place of Presentation
      カナダ・カルガリー市コンベンションセンター
    • Year and Date
      2009-08-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] PCR-RFLP法による Fasciola 属のITS1型の識別2009

    • Author(s)
      市川まどか, 板垣匡
    • Organizer
      第147回日本獣医学会学術集会
    • Place of Presentation
      栃木県総合文化センター
    • Year and Date
      2009-04-03
    • Related Report
      2009 Final Research Report
  • [Presentation] PCR-RFLP法によるFasciola属のITS1型の識別2009

    • Author(s)
      市川まどか、板垣匡
    • Organizer
      第147回日本獣医学会学術集会
    • Place of Presentation
      宇都宮市栃木県総合文化センター
    • Year and Date
      2009-04-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Fasciola hepaticaとF. giganticaの実験的な雑種F1形成2008

    • Author(s)
      板垣匡, ら
    • Organizer
      第77回日本寄生虫学会
    • Place of Presentation
      長崎市
    • Year and Date
      2008-04-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] 単為生殖型肝蛭の起源は中国か?中国産肝蛭の形態およびDNA型からみた考察2008

    • Author(s)
      市川まどか, 板垣匡, 柴原壽行, ペンモー
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎県
    • Related Report
      2009 Final Research Report
  • [Presentation] 中国産肝蛭における形態学及び分子遺伝学的解析2007

    • Author(s)
      彭毛、一之宮 美恵、鳳 麻衣子、柴原壽行、玄学南、杉本千尋、板垣 匡
    • Organizer
      第144回日本獣医学会学術集会
    • Place of Presentation
      江別市 酪農学園大学
    • Year and Date
      2007-09-02
    • Related Report
      2007 Annual Research Report
  • [Book] 動物病理学各論(日本獣医病理学会編)2010

    • Author(s)
      板垣匡(分担執筆)
    • Related Report
      2009 Final Research Report
  • [Book] 動物病理学各論第2版(日本獣医病理学会編)2010

    • Author(s)
      板垣匡, ら
    • Total Pages
      502
    • Publisher
      文永堂出版
    • Related Report
      2009 Annual Research Report
  • [Book] 獣医衛生動物学2009

    • Author(s)
      板垣匡(分担執筆)
    • Publisher
      講談社
    • Related Report
      2009 Final Research Report
  • [Book] 図説獣医衛生動物学2009

    • Author(s)
      今井壮一、藤崎幸蔵、板垣匡、森田達志
    • Total Pages
      325
    • Publisher
      講談社
    • Related Report
      2009 Annual Research Report
  • [Book] 最新家畜寄生虫病学 (今井壮一, 板垣匡, 藤崎幸蔵編)2007

    • Author(s)
      板垣匡(分担編集、分担執筆)
    • Publisher
      朝倉書店
    • Related Report
      2009 Final Research Report
  • [Book] 新獣医学辞典(新獣医学辞典編集委員会偏)2007

    • Author(s)
      板垣匡(分担執筆)
    • Related Report
      2009 Final Research Report
  • [Book] 最新家畜寄生虫病学2007

    • Author(s)
      今井壮一、板垣 匡、藤崎幸蔵編
    • Total Pages
      324
    • Publisher
      朝倉書店
    • Related Report
      2007 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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