Exploration of functions of porphyrin complex-decorated carbon nanotubes and their application to biological gas sensing
| Project/Area Number |
18H01829
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 28030:Nanomaterials-related
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
田畑 博史 大阪大学, 工学研究科, 助教 (00462705)
小松 直樹 京都大学, 人間・環境学研究科, 教授 (30253008)
久保 理 大阪大学, 工学研究科, 准教授 (70370301)
森川 良忠 大阪大学, 工学研究科, 教授 (80358184)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥17,680,000 (Direct Cost: ¥13,600,000、Indirect Cost: ¥4,080,000)
Fiscal Year 2021: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2019: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2018: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
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| Keywords | 半導体単層カーボンナノチューブ / 生体ガスセンサー / ガスバイオロジー / ポルフィリン錯体 / 銅環状化合物 / ナノコンポジット / 金属含有環状化合物 / ダイマー金属ポルフィリン錯体 / 金属ポルフィリン錯体 / モノマー金属ポルフィリン錯体 |
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| Outline of Final Research Achievements |
Metal porphyrin complex decorated carbon nanotubes are promissing sensing materials for the detection of trace amounts of biological gases in exhaled breath, becasuse they can be made highly selective to specific gases by selecting the central metal ions. In this study, we developed sensing materials for highly sensitive and selective detection of NH3. First, SWNTs decorated with Co dimer porphyrin complex acheved a response more than four times larger than those with conventional Co monomar porphyrin. Second, SWNTs surrounded with a Cu nanorectangle, a porlphyin-like molecule, showed a high selectivity for NH3 amoung various biological gases.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究で検知対象に選んだNH3は疾患マーカーの一種であり、腎機能障害患者では呼気中のNH3濃度が増加することが知られています。本研究で作製したCoダイマーポルフィリン錯体担持SWNTセンサーおよびCu環状化合物修飾SWNTセンサーを用いれば、この呼気中のNH3成分を夾雑成分の影響を受けずに高感度に検知することができるようになると期待され、呼気診断用ガスセンサーの小型化につながるものと考えています。
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Report
(5 results)
Research Products
(46 results)
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[Journal Article] Chemical stability of hydrogen boride nanosheets in water2021
Author(s)
Kurt Irvin Rojas, Nguyen Thanh Cuong, Hiroaki Nishino, Ryota Ishibiki, Shin-ichi Ito, Masahiro Miyauchi, Yoshitaka Fujimoto, Satoshi Tominaka, Susumu Okada, Hideo Hosono, Nelson Jr., Arboleda, Takahiro Kondo, Yoshitada Morikawa, Ikutaro Hamada
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Journal Title
Communications Materials 2 (2021) 81. (8 pages)
Volume: 2
Issue: 1
Pages: 1-8
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma2018
Author(s)
T.-F. Li, K. Li, Q. Zhang, C. Wang, Y. Yue, Z. Chen, S.-J. Yuan, X. Liu, Y. Wen, M. Han, N. Komatsu, Y.-H. Xu, L. Zhao,* X. Chen*
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Journal Title
Biomaterials
Volume: 181
Pages: 35-52
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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