| Co-Investigator(Kenkyū-buntansha) |
西村 幸男 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, プロジェクトリーダー (20390693)
谷 直樹 大阪大学, 大学院医学系研究科, 助教 (20598370)
押野 悟 大阪大学, 大学院医学系研究科, 准教授 (40403050)
柳澤 琢史 大阪大学, 高等共創研究院, 教授 (90533802)
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| Budget Amount *help |
¥33,930,000 (Direct Cost: ¥26,100,000、Indirect Cost: ¥7,830,000)
Fiscal Year 2022: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2021: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2020: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2019: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2018: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
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| Outline of Final Research Achievements |
The purpose of this study was to analyze and extract features in brain activity in spinal cord injury using neurophysiological methods to contribute to the recovery of neurological function in spinal cord injury (SCI) patients. To this end, primate SCI models were created as acute phase models. In addition, we recruited patients with SCI in the chronic phase and extracted physiological characteristics using invasive magnetoencephalography. As a result, changes in power in the γ-band and changes in phase amplitude coupling between phase in the β-band and power in the γ-band were observed in these patients after chronic spinal cord injury. These were also found to be changing during the recovery process in the acute SCI phase primate model. The physiological features obtained could be used as an indicator of neurofeedback to promote functional recovery.
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