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Phylogenomic approach to the early evolution of eukaryotes

Research Project

Project/Area Number 18K03820
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 17050:Biogeosciences-related
Research InstitutionUniversity of Tsukuba

Principal Investigator

Ishitani Yoshiyuki  筑波大学, 計算科学研究センター, 研究員 (60772043)

Co-Investigator(Kenkyū-buntansha) 氏家 由利香  高知大学, 教育研究部自然科学系理工学部門, 准教授 (20573041)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords有孔虫 / SAR / 分岐年代推定 / カンブリア紀 / 放散虫 / 大規模遺伝子データ / 真核生物 / 発現遺伝子解析 / 大規模データ
Outline of Final Research Achievements

Early evolution of eukaryotes is basic question not only for the Erath science but also exciting human's curiosity. Such fundamental question has been addressed by fossils, chemical proxies, and earth environmental changes (e.g., oxygen concentration). However, sediments in the early evolution of eukaryotes (possibly back to billions years ago) are limited and the preservation of fossils and organic matter is getting weaker and weaker through earth history. In present study, we tackle this question with molecular clock analysis based on genetic information which can collect large data from recent organisms. In eukaryotes, most organisms are single cell, and single cell eukaryotes spread in diverse group of eukaryotes. In present study, we collect genetic information single cell eukaryotes and fossilized eukaryotes to reveal early evolution of eukaryotes.

Academic Significance and Societal Importance of the Research Achievements

本研究により真核生物全体の大規模分岐年代推定用データセットを作成した。また、分岐年代推定方法の検定を行い、①疑わしい化石記録の検出や②高精度に推定する手法を見出した。このことから、分岐年代推定法がただの推定だけではなく、化石記録の妥当性の検証方法としても応用可能となった。また、今回得られた推定結果を事前確率として用いることで、生物群毎の分岐年代推定を高精度に行え、今後、分岐年代推定が多く行われることが期待される。
今回、得られたSARグループの分岐がカンブリア紀初期の所謂「カンブリア大爆発」の時期であったことは、生物多様化の理解や現生生物型の生態系がいつ整ったかを理解するのに大いに貢献した。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (11 results)

All 2020 2019 2018 Other

All Int'l Joint Research (3 results) Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (5 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Book (2 results)

  • [Int'l Joint Research] カリフォルニア大学(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] カリフォルニア大学(米国)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] カリフォルニア大学(米国)

    • Related Report
      2018 Research-status Report
  • [Journal Article] Nanoparticle-Biological Interactions in a Marine Benthic Foraminifer2019

    • Author(s)
      Ciacci Caterina、Grimmelpont Margot V.、Corsi Ilaria、Bergami Elisa、Curzi Davide、Burini Debora、Bouchet Vincent M. P.、Ambrogini Patrizia、Gobbi Pietro、Ujiie Yurika、Ishitani Yoshiyuki、Coccioni Rodolfo、Bernhard Joan M.、Frontalini Fabrizio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 19441-19441

    • DOI

      10.1038/s41598-019-56037-2

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Time-course analysis of gene expression of the benthic protist during exposed to the toxic heavy-metal.2020

    • Author(s)
      Ishitani, Y., Ujiie, Y., Ciacci, C., Fabrizio, F., Inagaki, Y.
    • Organizer
      JPGU-AGU Joint meeting 2020
    • Related Report
      2020 Annual Research Report
  • [Presentation] 有孔虫Ammonia beccariiのミトコンドリアに局在するDNA分子群.2019

    • Author(s)
      石谷佳之・久米慶太郎・稲垣祐司
    • Organizer
      日本共生生物学会2019年度大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 有孔虫の大規模分岐年代推定2019

    • Author(s)
      石谷佳之・矢崎裕規・氏家由利香・稲垣祐司
    • Organizer
      古生物学会2020年例会
    • Related Report
      2019 Research-status Report
  • [Presentation] 有孔虫の大規模分岐年代推定2019

    • Author(s)
      石谷佳之
    • Organizer
      高知大学海洋コア総合研究センター共同利用共同研究成果発表会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] Phylogenomic approach to the early evolution of Foraminifera.2018

    • Author(s)
      Ishitani, Y., UjiiEe, Y., Yazaki, E., Toyofuku, T., Nagai, Y., Inagaki, Y.
    • Organizer
      Forams 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Book] Paleobiology of the Polycystine Radiolaria2020

    • Author(s)
      Lazarus, D. Suzuki, N., Ishitani, Y., and Takahashi, K.
    • Total Pages
      504
    • Publisher
      Wiley-Blackwell
    • ISBN
      9780470671443
    • Related Report
      2020 Annual Research Report
  • [Book] アメーバのはなし2018

    • Author(s)
      永宗 喜三郎, 島野 智之, 矢吹 彬憲、丸山真一朗、八木田健司、福田康弘、中井裕、伊藤章、小林富美惠、野田悟子、平川泰久、白鳥峻志、廣岡裕吏、雪吹直史、松崎素道、石谷佳之、土屋正史、神川龍馬、中山卓郎、菅裕
    • Total Pages
      139
    • Publisher
      朝倉出版
    • ISBN
      9784254171686
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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