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Development of Fracture Avoidance AI Navigation ANZEN: From Diagnostics to Clinical Trials

Research Project

Project/Area Number 18K04179
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 21030:Measurement engineering-related
Research InstitutionKitasato University

Principal Investigator

Sakai Rina  北里大学, 医療衛生学部, 准教授 (10383647)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2021: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywords人工股関節全置換術 / 術中骨折 / 人工股関節置換術 / 人工股関節 / 周波数 / Total hip Arthloplasty / ハンマリング / ハンマリング音 / 周波数解析 / 医療機器
Outline of Final Research Achievements

We developed a THA support system that uses hammering sound to predict fractures during hip arthroplasty. The portability and ease of operation are important factors for medical staff when using the system. Therefore, we aimed to make the system compact and portable, and developed software to simplify its operation. A stick PC was adopted as the hardware and connected to the AI display. We succeeded in making the system much smaller than the originally envisioned tablet PC device. The system can be designed to alert the surgeon with a sound when the stem is fixed so that the surgeon can concentrate on the surgical field.

Academic Significance and Societal Importance of the Research Achievements

研究成果の意義は医療経済的観点からその有益性をもって社会に還元することにある.本課題において骨折予防法を確立した暁には,骨折した症例と比べ入院期間は1/6に短縮される(標準的入院期間:2-3週間,骨折を合併した場合の入院期間:2-3ヵ月).すなわち患者の生活の質を短期に改善できる点において,患者に対する臨床上の効果が著しい.人工股関節置換術の平均的入院費用は50万円(3割負担)であるのに対し,骨折を合併した場合の入院費用は300万円(3割負担)となる.すなわち本技術により医療費を大幅に削減できる可能性があり,経済的観点から大きな社会貢献につながる.

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (20 results)

All 2023 2022 2021 2020 2019 2018

All Journal Article (10 results) (of which Peer Reviewed: 10 results,  Open Access: 9 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Development of total hip arthroplasty support system for predicting intraoperative fractures by the frequency of hammering sound.2022

    • Author(s)
      Sakai R, Uchiyama K, Nishizawa S, Mizuhashi T, Yamamoto T, Yoshida K, Fukushima K, Takahira N,Ujihira M.
    • Journal Title

      Journal of Scientific & Technical Research

      Volume: 44(4) Issue: 4 Pages: 35685-35690

    • DOI

      10.26717/bjstr.2022.44.007081

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Selection of hammering sound collection devices for the development of total hip arthroplasty support systems.2022

    • Author(s)
      Sakai R, Uchiyama K, Nishizawa S, Mizuhashi T, Yamamoto T, Yoshida K, Fukushima K, Takahira N, Ujihira M.
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 15(7) Issue: 07 Pages: 179-186

    • DOI

      10.4236/jbise.2022.157016

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optimal clamping force of ultra high molecular weight polyethylene cable is 15 kgf.2022

    • Author(s)
      Sakai R, Yada T, Uchiyama K, Yoshida K, Yamamoto T, Ujihira M.
    • Journal Title

      Journal of Scientific & Technical Research

      Volume: 43(3) Issue: 3 Pages: 34585-34591

    • DOI

      10.26717/bjstr.2022.43.006904

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Investigation of hammering sound frequency during total hip arthroplasty to prevent intraoperative fracture.2021

    • Author(s)
      Sakai R, Kitazato T, Uchiyama K, Yoshida K, Yamamoto T, Takahira N, Ujihira M.
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 14(10) Issue: 10 Pages: 339-345

    • DOI

      10.4236/jbise.2021.1410029

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The contact pressure of ultra-high-molecular-weight polyethylene cables is twice as high as that of titanium cables.2021

    • Author(s)
      Sakai R, Yada T, Uchiyama K, Yoshida K, Ujihira M.
    • Journal Title

      Journal of Arthroscopy and Joint Surgery

      Volume: 8(3) Issue: 3 Pages: 276-281

    • DOI

      10.1016/j.jajs.2021.04.008

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hammering sound frequency analysis to fix an acetabular cup during total hip arthroplasty: Clinical trials and biomechanical studies.2021

    • Author(s)
      Sakai R, Uchiyama K., Kensuke F., Takahira N., Yoshida K, Ujihira M
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 14(1) Issue: 01 Pages: 14-20

    • DOI

      10.4236/jbise.2021.141003

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prediction of intraoperative fracture by hammering sound frequency analysis and stress estimation during total hip arthroplasty.2020

    • Author(s)
      Sakai R, Yamamoto T, Uchiyama K., Takahira N., Kakeshita M., Otsu Y, Yoshida K, Ujihira M.
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 13(6) Issue: 06 Pages: 113-119

    • DOI

      10.4236/jbise.2020.136011

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Usefulness of hammering sound frequency analysis as an evaluation method for the prevention of trouble during hip replacement.2020

    • Author(s)
      Sakai R, K. Uchiyama, N. Takahira, Kakeshita M , Otsu Y, Yoshida K, Ujihira M.
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 13(5) Issue: 05 Pages: 74-80

    • DOI

      10.4236/jbise.2020.135007

    • Related Report
      2020 Research-status Report 2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 人工股関節置換術におけるハンマリング音の周波数解析と大腿骨の応力の推定.2020

    • Author(s)
      酒井利奈,北里樹生,内山勝文,吉田和弘,高平尚伸,氏平政伸
    • Journal Title

      骨折

      Volume: 42(3) Pages: 1087-1090

    • Related Report
      2020 Research-status Report 2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Risk assessment of retrograde intramedullary nailing for proximal humeral fracture.2019

    • Author(s)
      Sakai R, Uchino M, Yoshida K, Ujihira M.
    • Journal Title

      Journal of Biomedical Science and Engineering

      Volume: 12(5) Issue: 05 Pages: 277-284

    • DOI

      10.4236/jbise.2019.125020

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 歩行荷重を考慮した人工股関節シェルの初期固定性評価方法.2023

    • Author(s)
      吉田和弘,大友佑,福島健介,酒井利奈,内山勝文,高平尚伸,氏平政伸
    • Organizer
      第42回バイオトライボロジシンポジウム
    • Related Report
      2022 Annual Research Report
  • [Presentation] 人工関節シェル初期固定性の新規評価法2022

    • Author(s)
      吉田和弘, 福島健介, 酒井利奈, 内山勝文, 高平尚伸, 氏平政伸
    • Organizer
      日本機械学会 第34回バイオエンジニアリング講演会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 生体内での力学環境を考慮した人工股関節シェルの初期固定性評価方法2022

    • Author(s)
      吉田和弘,大友佑,福島健介,酒井利奈,内山勝文,高平尚伸,氏平政伸
    • Organizer
      第49回日本臨床バイオメカニクス学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ステムをインプラントする際の骨質の違いによるハンマリング音の最大ピーク周波数の変化.2020

    • Author(s)
      5.北里樹生,酒井利奈,内山勝文,高平尚伸,大津恭男,掛下真広,吉田和弘,氏平政伸
    • Organizer
      第46回日本骨折治療学会-バーチャル学術集会-
    • Related Report
      2020 Research-status Report
  • [Presentation] Investigation of hammering sound frequency to prevent intraoperative fracture during hip replacement: examination in biomechanical materials.2019

    • Author(s)
      Kitazato T, Sakai R, Koyama M, Otsu Y, Kakeshita M, Usui T, Uchiyama K, Fukushima K, Takahira N, Yoshida K, Mabuchi K, Ujihira M
    • Organizer
      Biotribology Sendai 2019, The 11th International Biotribology Forum and the 40th Biotribology Symposium.
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 医工連携セッション 手を変えてみませんか?そのアイデアでInspire your ideal Change the surgery!医工連携による医療機器開発.2019

    • Author(s)
      酒井利奈
    • Organizer
      第45回日本骨折治療学会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 人工股関節置換術におけるハンマリング音の最大ピーク周波数の特定.2019

    • Author(s)
      北里樹生,酒井利奈,内山勝文,高平尚伸,大津恭男,掛下真広,薄井孝則,矢田藤暉,吉田和弘,馬渕清資,氏平政伸
    • Organizer
      第41回バイオトライボロジ研究会
    • Related Report
      2019 Research-status Report
  • [Presentation] 人工関節ステムをインプラントする際のハンマリング音の周波数解析.2019

    • Author(s)
      北里樹生,酒井利奈,大津恭男,掛下真広,薄井孝則,高平尚伸,内山勝文,吉田和弘,馬渕清資,氏平政伸
    • Organizer
      第46回日本臨床バイオメカニクス学会
    • Related Report
      2019 Research-status Report
  • [Patent(Industrial Property Rights)] 人工関節置換術における骨頭受け側コンポーネント設置不良防止システム2018

    • Inventor(s)
      北里研究所
    • Industrial Property Rights Holder
      北里研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2020
    • Related Report
      2020 Research-status Report
  • [Patent(Industrial Property Rights)] 医療用転子代替インプラント2018

    • Inventor(s)
      酒井利奈,高平尚伸,内田健太郎,馬渕清資
    • Industrial Property Rights Holder
      学校法人北里研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2019
    • Related Report
      2019 Research-status Report

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Published: 2018-04-23   Modified: 2024-01-30  

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