The mechanism of fish carbon dioxide anaesthesia to alleviate pain
Project/Area Number |
18K05830
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Review Section |
Basic Section 40040:Aquatic life science-related
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Research Institution | Kanazawa University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
渡邉 研一 東京農業大学, 生物産業学部, 教授 (20426315)
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Project Period (FY) |
2018-04-01 – 2021-03-31
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Project Status |
Completed (Fiscal Year 2020)
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Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Keywords | 魚類麻酔 / 炭酸 / ストレス / 可視化 / 魚類福祉 / 炭酸麻酔作用機序 / ストレス可視化 / 炭酸ガス / ストレス軽減 / 体表色彩 / 背地適応 / 両側回遊 / 炭酸取り込み / 炭酸麻酔 / 麻酔作用機序 / 苦痛軽減 |
Outline of Final Research Achievements |
It is unclear whether fish reduce the pain same as the anesthetic action (suppress nerve activity such as the brain and central nervous system) of mammal. Because fish are poikilotherm and respirate with the help of gills. In this study, we artificially caused stress in the backland-adapted fish Japanese flounder using potassium. And we succeeded in quantifying the change in body surface color, which is the first stress response. In addition, we investigated well-known stress factors as well. It was clarified that carbonic dioxide anesthesia is the most stress-relieving fish anesthesia.
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Academic Significance and Societal Importance of the Research Achievements |
麻酔に関する知見は哺乳類では豊富であるが、魚類の多くは水棲変温動物であり、代謝や呼吸中枢の酸素圧低下に対する耐性などがそれと異なるため、哺乳類の麻酔剤が使えないことも多い。本研究により、「炭酸」が、他の既存麻酔剤に比べ、ストレスを軽減することを見出した。この成果は現存するストレス軽減魚類麻酔剤として炭酸を各機関に紹介し、魚類福祉に大きく貢献できると確信している。
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Report
(4 results)
Research Products
(26 results)
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[Journal Article] Expression of sclerostin in the regenerating scales of goldfish and its increase under microgravity during space flight2020
Author(s)
Yamamoto, T., Ikegame, M., Hirayama, J., Kitamura, K., Tabuchi, Y., Furusawa, Y., Sekiguchi, T., Endo, M., Mishima, H., Seki, A., Yano, S., Matsubara H., Hattori, A. and Suzuki, N.
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Journal Title
Biomedical Research
Volume: 41
Issue: 6
Pages: 279-288
DOI
NAID
ISSN
0388-6107, 1880-313X
Year and Date
2020-12-01
Related Report
Peer Reviewed / Open Access
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[Journal Article] Detection of RANKL-producing cells and osteoclastic activation by the addition of exogenous RANKL in the regenerating scales of goldfish.2020
Author(s)
Yamamoto, T., Ikegame, M., Kawago, U., Tabuchi, Y., Hirayama, J., Sekiguchi, T., Furusawa, Y., Yachiguchi, K., Matsubara, H., Urata, M., Hattori, A. and Suzuki, N.
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Journal Title
Biological Science in Space
Volume: 34
Issue: 0
Pages: 34-40
DOI
NAID
Related Report
Peer Reviewed / Open Access
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[Presentation] シシャモの初期発生を制御する環境要因2019
Author(s)
林寛,高橋優太,大倉俊介,重松惇志,永見新,中尾勝哉,川崎琢真,山口浩志,横田高士,中野美和,春見達朗,鈴木信雄,松原創
Organizer
日本水産学会秋季大会
Related Report
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[Presentation] General aquaculture in Japan2018
Author(s)
Hajime Matsubara
Organizer
Joint Symposium between Kanazawa University and Prince of Songkla University on Recent Advances in Marine Science, Aquaculture and Food Technology
Related Report
Int'l Joint Research / Invited
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[Presentation] The carbon dioxide as fish anesthetic2018
Author(s)
Arata Nagami,Hiroshi,Kobayashi, Masakazu Kondoh and Hajime Matsubara
Organizer
Joint Symposium between Kanazawa University and Prince of Songkla University on Recent Advances in Marine Science, Aquaculture and Food Technology
Related Report
Int'l Joint Research
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