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Foundation of Biorefinary delivered from Bamboo Material

Research Project

Project/Area Number 18K05928
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 41050:Environmental agriculture-related
Research InstitutionTokyo Denki University

Principal Investigator

Shiiba Kiwamu  東京電機大学, 理工学部, 教授 (20621981)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords孟宗竹 / ヘミセルロース / 免疫賦活 / コレステロール低下作用 / 抗酸化作用 / バイオリファイナリー / バイオマス / 竹 / 抗酸化性 / コレステロール / 腸内細菌 / リグノヘミセルロース / 抗酸化 / 減圧マイクロ波処理 / クロマトグラフィー / LC/MS / バイリファイナリー / 桂皮酸類 / 抗酸化能 / NO産生 / 抗炎症性 / 免疫賦活作用
Outline of Final Research Achievements

For the first time in the world, we have developed a technology for separating and preparing components with various functionalities from bamboo by a soft method (low cost) without using special chemicals or solvents. From the environmental and cost perspectives, it was considered to use these as daily necessities and environmental materials in a biorefinery (cascade use) method.
The component extracted from bamboo, which is a promising biomass resource, by steam pressure treatment and cell wall disintegration enzyme (hereinafter abbreviated as BOS) contains oligosaccharides with a special structure as the main component, and this component has the effect of suppressing the rise in cholesterol. It was revealed that it has physiological effects such as antioxidant activity. Preliminary studies have shown that it may also have an immunostimulatory effect. We verified the elucidation of the mechanism of these physiological activities.

Academic Significance and Societal Importance of the Research Achievements

孟宗竹はイネ科であり国内外でその繁殖力の強さと地球温暖化の影響もあり、バイオマス量を増大させている。孟宗竹は、地球上でも最も成長速度の高い植物であり国内にも膨大なバイオマスが存在している。竹の繁殖分布は年々拡大しており、ほとんどは放置されている。そのため、自然林・人工林を侵食し枯死させ、地下茎が強固でないため、地盤が緩み土砂崩れを招きやすい等の「竹害」が発生し、問題が深刻化している。その一部は、これまでも筍や竹林景観としての利用等はあるが、利用は限定的であった。有望なバイオマス資源である竹から、生理効果を有する成分を抽出、最終的にはバイオ リファイナリーの基盤技術として確立できた。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (9 results)

All 2021 2020 2019 2018

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results) Book (1 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] Fecal Microbiota Perspective for Evaluation of Prebiotic Potential of Bamboo Hemicellulose Hydrolysate in Mice: A Preliminary Study2021

    • Author(s)
      Ikeyama Nao、Sakamoto Mitsuo、Ohkuma Moriya、Hiramoto Shigeru、Wang Jianpeng、Tone Shigenobu、Shiiba Kiwamu
    • Journal Title

      Microorganisms

      Volume: 9 Issue: 5 Pages: 888-888

    • DOI

      10.3390/microorganisms9050888

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 「竹バイオリファイナリー」孟宗竹中の健康に資する成分と孟宗竹の総合利用について2020

    • Author(s)
      椎葉究、平本茂、大平辰朗
    • Journal Title

      バイオインダストリー

      Volume: 37 Pages: 80-94

    • Related Report
      2020 Annual Research Report
  • [Journal Article] Dipeptide synthesis by internal adenylation domains of a multidomain enzyme involved in nonribosomal peptide synthesis2019

    • Author(s)
      Abe Tomoko、Kobayashi Kenta、Kawamura Sho、Sakaguchi Tatsuya、Shiiba Kiwamu、Kobayashi Michihiko
    • Journal Title

      The Journal of General and Applied Microbiology

      Volume: 65 Issue: 1 Pages: 1-10

    • DOI

      10.2323/jgam.2018.03.001

    • NAID

      130007608766

    • ISSN
      0022-1260, 1349-8037
    • Related Report
      2019 Research-status Report
  • [Presentation] 孟宗竹の総合利用に関する研究2019

    • Author(s)
      王建鵬 他
    • Organizer
      日本農芸化学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 孟宗竹ヘミセルロース加水分解物中の生理活性成分の分離と精製2019

    • Author(s)
      矢田堀裕聖 、関本智登、藤田誠史、布施有里奈、平本茂、椎葉究
    • Organizer
      日本農芸化学学会
    • Related Report
      2018 Research-status Report
  • [Book] Separatiion and Application of Pollutant-degradation Microbes from Sea2018

    • Author(s)
      Kiwamu Shiiba, Tomoko Abe
    • Total Pages
      51
    • Publisher
      LAMBERT
    • ISBN
      9783330003699
    • Related Report
      2018 Research-status Report
  • [Patent(Industrial Property Rights)] 免疫賦活組成物及び竹抽出物、ならびにその製造方法2020

    • Inventor(s)
      椎葉究
    • Industrial Property Rights Holder
      椎葉究
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-117462
    • Filing Date
      2020
    • Related Report
      2020 Annual Research Report
  • [Patent(Industrial Property Rights)] 2019-0100872019

    • Inventor(s)
      椎葉究、平本茂
    • Industrial Property Rights Holder
      東京電機大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Related Report
      2019 Research-status Report
  • [Patent(Industrial Property Rights)] 免疫賦活組成物及び竹抽出物、並びにそれらの製造方法2019

    • Inventor(s)
      椎葉究、平本茂
    • Industrial Property Rights Holder
      椎葉究、平本茂
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-010087
    • Filing Date
      2019
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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