Elucidation of the transmission and diffusion mechanism of antibacterial resistance in Salmonella that contaminates broilers
| Project/Area Number |
18K05997
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 42020:Veterinary medical science-related
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| Research Institution | Kagoshima University |
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Principal Investigator |
Chuma Takehisa 鹿児島大学, 農水産獣医学域獣医学系, 教授 (90201631)
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| Project Period (FY) |
2018-04-01 – 2022-03-31
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| Project Status |
Completed (Fiscal Year 2021)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | サルモネラ / 抗菌剤耐性 / ブロイラー |
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| Outline of Final Research Achievements |
In this study, we isolated Salmonella from the cecal contents of broilers in Kagoshima prefecture, investigated serotype and antimicrobial resistance, and attempted to elucidate the mode of the transmission. From 2018 to 2021, the Salmonella positive rates from individual chickens showed an increasing trend of 12.5, 13.4, 21.6 and 23.6%, respectively, and the positive rates of chicken flock were 72.9%, 72.9%, 89.6% and 93.8%, respectively. As a result of antimicrobial susceptibility testing, ABPC, CTX, and CFX resistance were no longer observed in 2018. On the other hand, from 2018 to 2020, the isolation rate of S. Schwarzengrund increased and KM resistance increased, strongly suggesting a relationship between serotype and resistance acquisition.
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| Academic Significance and Societal Importance of the Research Achievements |
食中毒の原因菌であり近年では薬剤耐性菌の出現も問題視されているサルモネラのブロイラー農場レベルにおける汚染状況が明らかとなった。サルモネラの抗菌剤感受性が近年大きく変化している傾向が認められ、今後の薬剤使用のための有力な情報となった。サルモネラの抗菌剤耐性獲得のメカニズムとして血清型との関わりが示され、抗菌剤耐性菌の蔓延防止につながる可能性がある。
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Report
(5 results)
Research Products
(11 results)
