Evolution of cervical muscular and nervous systems from the aspect of comparative and experimental developmental biology
| Project/Area Number |
18K06822
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 48010:Anatomy-related
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 軸上 / 軸下 / 筋 / 神経 / 発生 / 解剖 / ボディプラン / 実験発生学 / 比較形態学 |
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| Outline of Final Research Achievements |
Trunk muscles in vertebrates have morphologically been divided into dorsal epaxial and ventral hypaxial muscles. The latter contains limb muscles and the other hypaxial muscles, which is based on their development. These three types of muscles are innervated by three types of motor neurons, respectively. We analyzed the development of shoulder muscles and their motor neurons, and found transitional muscles between the epaxial and hypaxial muscles, for which we coined the term “midaxial muscles”.
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| Academic Significance and Societal Importance of the Research Achievements |
これまで脊椎動物の胴体の筋はそれを支配する神経の形態から背側部分と腹側部分の二つに分けられてきた。今回、神経で働く分子を調べ、この二つの間に移行帯が存在することを明らかにした。頭尾軸においても頭部の筋と体幹の筋の間には移行帯が存在することが近年明らかにされており、脊椎動物の体が背側か腹側か、頭部か体幹かといった二項対立的なものではなく、ある程度の勾配を持って変化している構造であることが分かった。
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Report
(4 results)
Research Products
(6 results)
