| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Outline of Final Research Achievements |
The purpose of this study was to clarify the pathological mechanism of the onset of equilibrium sensory dysfunction through the elucidation of the functional role of the onset of equilibrium sensory dysfunction and the gap junction of vestibular hair cells. Treatment with carbenoxolone (CBX), a gap junction inhibitor into the inner ear of mice, caused morphological abnormalities of vestibular hair cells and reduced gap junction function. Antioxidants tempol and NAC tended to suppress the decline in gap junction function due to CBX treatment.
|
